Patents by Inventor Gintautas Zvirblis

Gintautas Zvirblis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Derivatives of recombinant proteins, homo-multimers of granulocyte colony-stimulating factor and method of preparation thereof
    Patent number: 9243049
    Abstract: The invention relates to derivatives of recombinant proteins, comprising homo-multimers of genetically fused recombinant biologically active protein monomer units, connected via selected peptide linker moiety; and the method of preparation thereof. Derivative of recombinant protein is preferably dimer of human granulocyte colony-stimulating factor, characterised by increased circulation time in vivo.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: January 26, 2016
    Assignee: UAB Profarma
    Inventors: Edita Mistiniene, Jonas Henrikas Pesliakas, Milda Pleckaityte, Gintautas Zvirblis
  • DERIVATIVES OF RECOMBINANT PROTEINS, HOMO-MULTIMERS OF GRANULOCYTE COLONY-STIMULATING FACTOR AND METHOD OF PREPARATION THEREOF
    Publication number: 20140193357
    Abstract: The invention relates to derivatives of recombinant proteins, comprising homo-multimers of genetically fused recombinant biologically active protein monomer units, connected via selected peptide linker moiety; and the method of preparation thereof. Derivative of recombinant protein is preferably dimer of human granulocyte colony-stimulating factor, characterised by increased circulation time in vivo.
    Type: Application
    Filed: August 9, 2011
    Publication date: July 10, 2014
    Inventors: Edita Mistiniene, Jonas Henrikas Pesliakas, Milda Pleckaityte, Gintautas Zvirblis
  • Method for purifying granulocyte-colony stimulating factor
    Publication number: 20070293660
    Abstract: The present invention provides a novel process for isolating and purifying rmetHuG-CSF from a G-CSF producing microorganism. The invention also relates to a method of improved over-expression of G-CSF in E. coli., a primer sequence for amplification of a modified hG-CSF sequence, plasmids, expression vestors and host cells for use in such an improved method.
    Type: Application
    Filed: March 20, 2007
    Publication date: December 20, 2007
    Inventors: Vladas Bumelis, Loreta Janeniene, Jonas Pesliakas, Jurate Rimkeviciene, Arunas Vaitkevicius, Giedrius Zunda, Gintautas Zvirblis