Patents by Inventor Giorgia Salvagiotto

Giorgia Salvagiotto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for the differentiation of stem cells
    Patent number: 8557580
    Abstract: The present invention provides methods and compositions for the production of hematopoietic progenitor cells or endothelial progenitor cells from human pluripotent stem cells using a defined cell culture medium without the need to utilize feeder cells or serum. In some embodiments, differentiation is accomplished using hypoxic atmospheric conditions. The defined medium of the present invention may contain growth factors and a matrix component. The hematopoietic progenitor cells may be further differentiated into cell lineages including red blood cells, macrophages, granulocytes, and megakaryocytes. The endothelial progenitor cells may be further differentiated into endothelial cells. Also disclosed are screening assays for identification of candidate substances that affect differentiation of pluripotent stem cells into progenitor cells.
    Type: Grant
    Filed: February 22, 2010
    Date of Patent: October 15, 2013
    Assignee: Cellular Dynamics International, Inc.
    Inventors: Christine Daigh, Peter Fuhrken, Giorgia Salvagiotto
  • METHODS AND COMPOSITIONS FOR THE DIFFERENTIATION OF STEM CELLS
    Publication number: 20100216181
    Abstract: The present invention provides methods and compositions for the production of hematopoietic progenitor cells or endothelial progenitor cells from human pluripotent stem cells using a defined cell culture medium without the need to utilize feeder cells or serum. In some embodiments, differentiation is accomplished using hypoxic atmospheric conditions. The defined medium of the present invention may contain growth factors and a matrix component. The hematopoietic progenitor cells may be further differentiated into cell lineages including red blood cells, macrophages, granulocytes, and megakaryocytes. The endothelial progenitor cells may be further differentiated into endothelial cells. Also disclosed are screening assays for identification of candidate substances that affect differentiation of pluripotent stem cells into progenitor cells.
    Type: Application
    Filed: February 22, 2010
    Publication date: August 26, 2010
    Applicant: CELLULAR DYNAMICS INTERNATIONAL, INC.
    Inventors: Christine Daigh, Peter Fuhrken, Giorgia Salvagiotto