Patents by Inventor Giorgio Long

Giorgio Long has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,4-disubstituted piperazines useful in the therapy of the asthma and of the inflammation of the respiratory tract
    Patent number: 5607930
    Abstract: Compounds of formula (I): ##STR1## wherein Ra, Rb, B and D have the meanings reported in the disclosure, processes for making the same, and methods of using the same in the treatment of asthma and/or inflammation of the respiratory tract are disclosed.
    Type: Grant
    Filed: March 28, 1995
    Date of Patent: March 4, 1997
    Assignee: Boehringer Mannheim Italia, S.p.A.
    Inventors: Giorgio Long, Silvano Spinelli, Antonella Rozzi, Simonetta D'Alo', Licia Gallico
  • [3H,7H]thiazole[3,4-a]pyridines having antiasthmatic and antiinflammatory activities on the respiratory tract
    Patent number: 5464844
    Type: Grant
    Filed: June 2, 1994
    Date of Patent: November 7, 1995
    Assignee: Boehringer Mannheim Italia, S.p.A.
    Inventors: Giorgio Long, Giampiero De Cillis, Antonella Rozzi, Simonetta D'Alo, Licia Gallico
  • Heterocyclic amines useful in the therapy of asthma and imflammation of the respiratory tract
    Patent number: 5453423
    Abstract: Compounds of the formula ##STR1## wherein A, Y, X, B and D are described in the specification are disclosed. The compounds possess activity in treating asthma and other pathologies of the respiratory tract.
    Type: Grant
    Filed: September 27, 1993
    Date of Patent: September 26, 1995
    Assignee: Boehringer Mannheim Italia S.p.A.
    Inventors: Giorgio Long, Carmelo A. Gandolfi, Gianpiero De Cillis, Roberto Di Domenico, Antonella Rozzi, Licia Gallico
  • [3H,7H]thiazolo[3,4-a]pyridines with antiasthmatic and antiinflammatory actions on the respiratory tract
    Patent number: 5336676
    Abstract: Compounds of formula (I) ##STR1## wherein R is an alkyl group; R.sub.1 is a cyano, carboxy, alkoxycarbonyl or hydroxylaminocarbonyl group; R.sub.2 is substituted or unsubstituted phenyl (C.sub.3 -C.sub.7)-cycloalkyl, .alpha.-, .beta.- or .gamma.-pyridyl or a benzoheteroxcyclic ring; R.sub.3 is carboxy or carboalkoxy; Y is a group of the formula --COOX; --NHCOA; --NCO; --COA; --CONHOR.sub.e ; --OCOA; A; --COCH.sub.2 COR.sub.f ; --NHCSA; --OCSA; (a); X is hydrogen, alkyl or succinimidyl group; A is a cyclic or acyclic amino group; and n is 1 or 2; having pharmacological characteristics which render them useful in the treatment of inflammatory conditions of the respiratory tract and asthmatic conditions.
    Type: Grant
    Filed: December 4, 1992
    Date of Patent: August 9, 1994
    Assignee: Boehringer Mannheim Italia S.p.A.
    Inventors: Carmelo A. Gandolfi, Giampiero De Cillis, Giorgio Long, Licia Gallico
  • Process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines
    Patent number: 5245039
    Abstract: A process for the optical resolution of racemic 1,4-dihydropyridines, containing isothioureido groups. Salification of racemic isothioureas with optically active acids produces diasteroisomeric mixtures of isothiouronium salts, that, using conventional techniques, are separated in the individual components to give optically pure isothioureides of 1,4-dihydropyridines and salts thereof with conventional acids. Said optically pure 1,4-dihydropyridines can then be subjected to desulphuration and to different transformations to give to other enantiomerically pure and therapeutically useful 1,4-dihydropyridines.
    Type: Grant
    Filed: August 14, 1991
    Date of Patent: September 14, 1993
    Assignee: Boehringer Mannheim Italia
    Inventors: Carmelo A. Gandolfi, Marco Frigerio, Carlo Riva, Andrea Zaliani, Giorgio Long, Roberto D. Domenico