Patents by Inventor Giorgio Stassi

Giorgio Stassi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY SPECIFIC FOR HUMAN IL-4 FOR THE TREATMENT OF CANCER
    Publication number: 20100297110
    Abstract: The present invention relates to the use of an antibody or an antigen-binding fragment thereof with specific binding activity for human interleukin-4 for the prevention and/or treatment of cancer.
    Type: Application
    Filed: March 21, 2007
    Publication date: November 25, 2010
    Applicant: APOGENIX GMBH
    Inventors: Thomas Hoeger, Juergen Gamer, Giorgio Stassi, Matilde Todaro
  • Sensitizing Cells for Apoptosis by Selectively Blocking Cytokines
    Publication number: 20100099742
    Abstract: The invention refers to the use of a cytokine antagonist which modulates the expression and/or the function of a cytokine, particularly a Th2 helper cell cytokine, in a cell and causes the down-regulation of anti-apoptotic proteins in said cell through the cytokine modulation for sensitizing cells for apoptosis. In particular, the cells that can be treated with the cytokine antagonists are drug-resistant cancer cells which fail to undergo apoptosis.
    Type: Application
    Filed: November 30, 2009
    Publication date: April 22, 2010
    Inventors: Giorgio Stassi, Matilde Todaro
  • Sensitizing cells for apoptosis by selectively blocking cytokines
    Patent number: 7645449
    Abstract: The invention refers to the use of a cytokine antagonist which modulates the expression and/or the function of a cytokine, particularly a Th2 helper cell cytokine, in a cell and causes the down-regulation of anti-apoptotic proteins in said cell through the cytokine modulation for sensitizing cells for apoptosis. In particular, the cells that can be treated with the cytokine antagonists are drug-resistant cancer cells which fail to undergo apoptosis.
    Type: Grant
    Filed: February 9, 2004
    Date of Patent: January 12, 2010
    Inventors: Giorgio Stassi, Matilde Todaro
  • DIFFERENTIAL CYTOKINE EXPRESSION IN HUMAN CANCER
    Publication number: 20090324616
    Abstract: The invention concerns a method for diagnosing a cancer type, whereby the expression of anti-apoptotic cytokines is determined in the tumour cells. The differential diagnosis of the present invention is used to classify tumour disorders and to recommend the required treatment and to monitor the progress and response to the treatment.
    Type: Application
    Filed: June 21, 2007
    Publication date: December 31, 2009
    Inventors: Giorgio Stassi, Christian Gieffers, Oliver Hill, Meinolf Thiemann, Matilde Todaro
  • Method for the Purification and Amplification of Tumoral Stem Cells
    Publication number: 20070292389
    Abstract: The invention concerns a method for the purification and amplification in the undifferentiated state of tumoral stem cells form solid tumours which are most resistant to conventional therapies, aiming at devising new tumour markers and therapeutic targets both for early diagnosis and for targeted therapeutic strategies.
    Type: Application
    Filed: September 14, 2005
    Publication date: December 20, 2007
    Applicant: Apogenix GmbH
    Inventors: Giorgio Stassi, Matilde Todaro
  • Sensitizing cells for apoptosis by selectively blocking cytokines
    Publication number: 20060257401
    Abstract: The invention refers to the use of a cytokine antagonist which modulates the expression and/or the function of a cytokine, particularly a Th2 helper cell cytokine, in a cell and causes the down-regulation of anti-apoptotic proteins in said cell through the cytokine modulation for sensitizing cells for apoptosis. In particular, the cells that can be treated with the cytokine antagonists are drug-resistant cancer cells which fail to undergo apoptosis.
    Type: Application
    Filed: February 9, 2004
    Publication date: November 16, 2006
    Inventors: Giorgio Stassi, Maltilde Todaro