Patents by Inventor Giorgio TORTAROLO

Giorgio TORTAROLO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11422348
    Abstract: A method for operating a point laser-scanning microscope includes scanning a sample with a focused illumination laser beam; recording a plurality of images by detecting elements being configurable to an intensity mode, in which the recorded images are intensity images gi,j(n) related to photons collected during an entire dwell time of the illumination beam on an individual position n, or to a time-resolved mode, in which the recorded images are time-resolved images gi,jt(n, t), the collected photons being discriminated based on their arrival times to individual detecting elements; calculating a fingerprint image a by summing the plurality of intensity images gi,j(n) over all positions n; estimating shift matrices sx and sy from the intensity images gi,j(n); reconstructing at least one of a time-resolved object function ft and an intensity object function f; and visualizing at least one of a high-resolution time-resolved image ft˜ and a high-resolution intensity image f˜.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: August 23, 2022
    Assignees: FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA, POLITECNICO DI MILANO, UNIVERSITA' DEGLI STUDI DIGENOVA
    Inventors: Giuseppe Vicidomini, Marco Castello, Giorgio Tortarolo, Alberto Tosi, Mauro Buttafava, Federica Villa, Paolo Bianchini, Alberto Diaspro, Colin J. R. Sheppard
  • Publication number: 20200386974
    Abstract: A method for operating a point laser-scanning microscope comprises scanning a sample with a focused illumination laser beam; recording a plurality of images by detecting elements being configurable to an intensity mode, in which the recorded images are intensity images gi,j(n) related to photons collected during an entire dwell time of the illumination laser beam on an individual position n, or to a time-resolved mode, in which the recorded images are time-resolved images gi,jt(n,t), the collected photons being discriminated based on their arrival times to individual detecting elements; calculating a fingerprint image a by summing the plurality of intensity images gi,j(n) over all positions n; estimating shift matrices sx and sy from the intensity images gi,j(n); reconstructing at least one of a time-resolved object function ft and an intensity object function f; and visualizing at least one of a high-resolution time-resolved image ft˜ and a high-resolution intensity image f˜.
    Type: Application
    Filed: January 24, 2019
    Publication date: December 10, 2020
    Inventors: Giuseppe VICIDOMINI, Marco CASTELLO, Giorgio TORTAROLO, Alberto TOSI, Mauro BUTTAFAVA, Federica VILLA, Paolo BIANCHINI, Alberto DIASPRO, Colin J.R. SHEPPARD