Patents by Inventor Giovanna La Rana

Giovanna La Rana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Galactosylated pro-drugs of non-steroidal anti-inflammatories with improved pharmacokinetic characteristics and reduced toxicity of the starting drug
    Patent number: 8551958
    Abstract: Pro-drugs of all non-steroidal anti-inflammatories with free acid function derivatized with an ester group, which have the general structural formula given below (I) where A is: aspirin, diflunisal, benorylate, ibufenac, diclofenac, indomethacin, sulindac, ketorolac, ibuprofen, naproxen, ketoprofen, fenoprofen, flurbiprofen, mefenamic acid, meclof enamic acid, flufenamic acid, niflumic acid, and where in the ester group R can be a sugar (amongst which aldose, or ketose pentose, or esose selected from a group of D- and L-enantioiuers of ribose, glucose, galactose, mannose, arabinose, xilose, allose, altrose, gulose, idose and talose and substituted derivatives thereof, such as glucosamine, galactosamine, N-acetyl glucosamine, N-acetyl galactosamine, N-acetyl ribosamine), a disaccharide, a trisaccharide or an oligosaccharide.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: October 8, 2013
    Assignees: Stewart Italia Srl
    Inventors: Maria Grazia Rimoli, Antonio Calignano, Rosario Cuomo, Gianpiero Boatto, Enrico Abignente, Daniela Melisi, Annalisa Curcio, Elvira Luongo, Giovanna La Rana, Oscar Sasso, Giovanni Sarnelli, Roberto Russo, Maria Nieddu, Carla Cirillo, Salvatore De Lucia
  • GALACTOSYLATED PRO-DRUGS OF NON-STEROIDAL ANTI-INFLAMMATORIES WITH IMPROVED PHARMACOKINETIC CHARACTERISTICS AND REDUCED TOXICITY OF THE STARTING DRUG
    Publication number: 20110212904
    Abstract: Pro-drugs of all non-steroidal anti-inflammatories with free acid function derivatized with an ester group, which have the general structural formula given below (I) where A is: aspirin, diflunisal, benorylate, ibufenac, diclofenac, indomethacin, sulindac, ketorolac, ibuprofen, naproxen, ketoprofen, fenoprofen, flurbiprofen, mefenamic acid, meclof enamic acid, flufenamic acid, niflumic acid, and where in the ester group R can be a sugar (amongst which aldose, or ketose pentose, or esose selected from a group of D- and L-enantioiuers of ribose, glucose, galactose, mannose, arabinose, xilose, allose, altrose, gulose, idose and talose and substituted derivatives thereof, such as glucosamine, galactosamine, N-acetyl glucosamine, N-acetyl galactosamine, N-acetyl ribosamine), a disaccharide, a trisaccharide or an oligosaccharide.
    Type: Application
    Filed: January 28, 2011
    Publication date: September 1, 2011
    Applicants: STEWART ITALIA SRL
    Inventors: Maria Grazia RIMOLI, Antonio CALIGNANO, Rosario CUOMO, Gianpiero BOATTO, Enrico ABIGNENTE, Daniela MELISI, Annalisa CURCIO, Elvira LUONGO, Giovanna LA RANA, Oscar SASSO, Giovanni SARNELLI, Roberto RUSSO, Maria NIEDDU, Carla CIRILLO, Salvatore DE LUCIA
  • Control of pain with endogenous cannabinoids
    Patent number: 6656972
    Abstract: Novel pharmaceutical therapeutic compositions and methods for using same for the treatment of pain experienced by an individual are provided. The compositions contain at least one member selected from among anandamide and palmitylethanolamide.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: December 2, 2003
    Assignees: Neurosciences Research Foundation, Inc., Universita di Napoli Federico II
    Inventors: Antonio Calignano, Giovanna La Rana, Andrea Guiffrida, Daniele Piomelli
  • Control of pain with endogenous cannabinoids
    Publication number: 20020173550
    Abstract: Novel pharmaceutical therapeutic compositions and methods for using same for the treatment of pain experienced by an individual are provided.
    Type: Application
    Filed: January 22, 2002
    Publication date: November 21, 2002
    Inventors: Antonio Calignano, Giovanna La Rana, Andrea Guiffrida, Daniele Piomelli
  • Control of pain with endogenous cannabinoids
    Patent number: 6348498
    Abstract: Novel pharmaceutical therapeutic compositions and methods for using same for the treatment of pain experienced by an individual are provided. The compositions contain at least one member selected from among anandamide and palmitylethanolamide.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: February 19, 2002
    Assignee: Neurosciences Research Foundation, Inc.
    Inventors: Antonio Calignano, Giovanna La Rana, Andrea Guiffrida, Daniele Piomelli