Patents by Inventor Giovanna Libralon

Giovanna Libralon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, its method of production and use
    Patent number: 9540328
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: January 10, 2017
    Assignee: ALLERGAN, INC.
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • (-)-(2R,3S)-2-AMINO-3-HYDROXY-3-PYRIDIN-4-YL-1-PYRROLIDIN-1-YL-PROPAN-1-ONE (L)-(+) TARTRATE SALT, ITS METHOD OF PRODUCTION AND USE
    Publication number: 20160347712
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Application
    Filed: December 21, 2015
    Publication date: December 1, 2016
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • (-)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+) tartrate salt, its method of production and use
    Patent number: 9242935
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+)tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Grant
    Filed: August 14, 2014
    Date of Patent: January 26, 2016
    Assignee: ALLERGAN, INC.
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • ( ) (2R,3S)-2-AMINO-3-HYDROXY-3-PYRIDIN-4-YL-1-PYRROLIDIN-1-YL-PROPAN-1-ONE (L)-(+) TARTRATE SALT, ITS METHOD OF PRODUCTION AND USE
    Publication number: 20150051253
    Abstract: The present invention is directed to (?)-(2R,3S)-2-amino-3-hydroxy-3-pyridin-4-yl-1-pyrrolidin-1-yl-propan-1-one (L)-(+)tartrate salt, a pharmaceutical composition comprising said salt, a process for making said salt, and the use of said salt in the treatment of pain.
    Type: Application
    Filed: August 14, 2014
    Publication date: February 19, 2015
    Inventors: Gyorgy F. Ambrus, Katherine C. Kurjan, Jacopo Zanon, Giovanna Libralon, Carla De Faveri
  • Methods for preparing ritodrine hydrochloride
    Patent number: 8912360
    Abstract: Methods for preparing Ritodrine hydrochloride are provided. Also provided is non-hygroscopic, crystalline, polymorphic Ritodrine hydrochloride of Form I.
    Type: Grant
    Filed: March 24, 2011
    Date of Patent: December 16, 2014
    Assignee: Lundbeck Pharmaceuticals Italy S.p.A.
    Inventors: Jacopo Zanon, Giovanna Libralon, Carla De Faveri, Florian Anton Martin Huber
  • Method for preparing argatroban monohydrate and a process for its synthesis
    Patent number: 8378106
    Abstract: A method is described for preparing argatroban monohydrate obtained from (2R,4R)-1-[NG-nitro-N2-(3-methyl-8-quinolinesulphonyl)-L-arginyl]-4-methyl-2-piperidine carboxylic acid by suitably treating crude argatroban. The method either comprises preparation of argatroban monohydrate in a continuous step or an intermediate step of isolating a purified argatroban. Also obtainable from argatroban monohydrate is anhydrous argatroban, shown to have new physico-chemical characteristics. The described argatroban synthesis and purification process hence enables three different forms of argatroban, not previously described, to be obtained, each with distinctive physico-chemical characteristics and in particular enables argatroban monohydrate to be obtained with high yield and with high purity, being therefore a product suitable for use as active principle in proprietary medicines.
    Type: Grant
    Filed: April 6, 2009
    Date of Patent: February 19, 2013
    Assignee: Lundbeck Pharmaceuticals Italy S.p.A.
    Inventors: Jacopo Zanon, Giovanna Libralon, Andrea Nicole′
  • METHOD FOR PREPARING ARGATROBAN MONOHYDRATE AND A PROCESS FOR ITS SYNTHESIS
    Publication number: 20110028726
    Abstract: A method is described for preparing argatroban monohydrate obtained from (2R,4R)-1-[NG-nitro-N2-(3-methyl-8-quinolinesulphonyl)-L-arginyl]-4-methyl-2-piperidine carboxylic acid by suitably treating crude argatroban. The method either comprises preparation of argatroban monohydrate in a continuous step or an intermediate step of isolating a purified argatroban. Also obtainable from argatroban monohydrate is anhydrous argatroban, shown to have new physico-chemical characteristics. The described argatroban synthesis and purification process hence enables three different forms of argatroban, not previously described, to be obtained, each with distinctive physico-chemical characteristics and in particular enables argatroban monohydrate to be obtained with high yield and with high purity, being therefore a product suitable for use as active principle in proprietary medicines.
    Type: Application
    Filed: April 6, 2009
    Publication date: February 3, 2011
    Inventors: Jacopo Zanon, Giovanna Libralon, Andrea Nicole