Abstract: Novel derivatives of 11-carbonyl-6,11-dihydrodibenzo[c,f][1,2,5]thiadiazepine 5,5-dioxide of the general formula ##STR1## wherein R and R.sub.1, which can be different, represent a hydrogen atom or a (C.sub.1 -C.sub.5) alkyl or (C.sub.1 -C.sub.4)hydroxyalkyl group, or R and R.sub.1 together can form a 5-membered and/or 6-membered heterocyclic ring which may contain a further heteroatom,R.sub.2 and R.sub.3, which can be different, represent a hydrogen atom, a (C.sub.1 -C.sub.3)alkoxy, (C.sub.1 -C.sub.3)alkyl, nitro, amino or (C.sub.1 -C.sub.3)alkylamino, halogen, halogeno-alkyl or hydroxyl group,R.sub.4 represents a hydrogen atom or a (C.sub.1 -C.sub.4) alkyl, alkylaryl or (C.sub.1 -C.sub.6)alkylamino group, andn assumes values of 0, 1 or 2, andnon-toxic, pharmaceutically acceptable salts thereof, obtained by addition of acids or alkyl halides.

Abstract: A pharmacologically active compound has the general formula ##STR1## in which R is a hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; R.sub.1 and R.sub.2, which can be different, represent a hydrogen atom, a hydroxyl group, an alkyl group, an alkoxy group, an arylalkyl group, or an arylalkoxy group, or can jointly represent an oxygen atom or a CHCOOR.sub.1 ' group where R.sub.1 ' is a hydrogen atom or an alkyl group; and R.sub.3 represents a hydrogen or halogen atom or an alkyl, NH.sub.2, NO.sub.2, NHCO-alkyl, NHCO-aryl, NHCONH-alkyl or NHCOHN-aryl group.These compounds act on the central nervous system and have an anti-convulsant sedative activity.

Abstract: A compound for use as a normolipidemizer and/or a platelet anti-binder in therapy, and pharmaceutical compositions containing the compound.

Abstract: A compound having pharmacological properties comprising the structural formula ##STR1## wherein R is selected from the isopropyl, n-octyl, n-butyl or isobutyl groups; R.sub.1 is selected from the 1-naphthyloxymethyl, (2-allylphenoxy)-methyl, 4-nitrophenyl, {2-[(tetrahydrofurfuryl)oxy-]-phenoxy}-methyl, [4-(2-methoxyethyl)phenoxy]methyl, 4-isopropylthiophenyl, 4-acetaminophenoxymethyl groups; and R.sub.2 represents a hydrogen atom or a methyl group. A method for synthetizing the compound is also disclosed comprising the cyclization of aminoalcohol or halogenurethane.

Abstract: New compounds useful as spasmolytic agents are provided with the following formula: ##STR1## wherein n is either 2 or 3. In addition, salts of these new compounds are provided and are suitable for oral as well as parenteral administration to animals and man as spasmolytic agents. In compositions for oral and parenteral or rectal administration, from about 5 to about 40 mg of active ingredient per dosage unit is used. The bromide and iodide salts of these new compounds are especially useful.

Abstract: This invention relates to the use of 2-(1-chloro-2-yloxy) propionic acid and its derivatives having physiological activity, notably as antiphlogistics, analgesics, analgesics and anti-pyretics. The physiologically active compounds include esters and amides of the substituted propionic acid. The compounds can be presented in conventional pharmaceutical form, including the non-toxic, pharmaceutically acceptable salts thereof.