Patents by Inventor Giovanni AMABILE

Giovanni AMABILE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TMEM219 antibodies and therapeutic uses thereof
    Patent number: 12221485
    Abstract: The present invention relates to antibodies or antigen binding fragments thereof that bind specifically to the IGFBP3 receptor, namely TMEM219, to methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Grant
    Filed: July 12, 2024
    Date of Patent: February 11, 2025
    Assignee: ENTHERA S.R.L.
    Inventors: Paolo Fiorina, Giovanni Amabile, Francesca D'Addio
  • TMEM219 ANTIBODIES AND THERAPEUTIC USES THEREOF
    Publication number: 20240368290
    Abstract: The present invention relates to antibodies or antigen binding fragments thereof that bind specifically to the IGFBP3 receptor, namely TMEM219, to methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: July 12, 2024
    Publication date: November 7, 2024
    Inventors: Paolo FIORINA, Giovanni AMABILE, Francesca D'ADDIO
  • TMEM219 ANTIBODIES AND THERAPEUTIC USES THEREOF
    Publication number: 20230242649
    Abstract: The present invention relates to antibodies or antigen binding fragments thereof that bind specifically to the IGFBP3 receptor, namely TMEM219, to methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: November 16, 2020
    Publication date: August 3, 2023
    Inventors: Paolo FIORINA, Giovanni AMABILE, Francesca D'ADDIO
  • INHIBITORS AND USES THEREOF
    Publication number: 20230192827
    Abstract: The present invention relates to inhibitors of IGFBP5 and/or of at least one of its receptors, wherein said inhibitor has anti-fibrotic effect, methods for their production, pharmaceutical compositions containing said inhibitors, and uses thereof. In particular, the invention relates to antibodies or antigen binding fragments thereof that bind specifically to human IGFBP5 and/or to at least one of its receptors.
    Type: Application
    Filed: February 19, 2021
    Publication date: June 22, 2023
    Inventor: Giovanni AMABILE
  • IGFBP3 ANTIBODIES AND THERAPEUTIC USES THEREOF
    Publication number: 20230039165
    Abstract: The present invention relates to antibodies or antigen binding fragment thereof that binds specifically to IGFBP3. The antibody inhibits or reduces the binding of IGFBP3 to the TMEM219 receptor. The invention also relates to methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
    Type: Application
    Filed: November 20, 2020
    Publication date: February 9, 2023
    Inventors: Giovanni AMABILE, Paolo FIORINA, Francesca D'ADDIO