Patents by Inventor Giovanni Monteleone

Giovanni Monteleone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field
    Publication number: 20150218561
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: February 3, 2015
    Publication date: August 6, 2015
    Inventor: Giovanni Monteleone
  • Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field
    Patent number: 9096854
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: August 4, 2015
    Assignee: Nogra Pharma Limited
    Inventor: Giovanni Monteleone
  • Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field
    Publication number: 20150211011
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: April 13, 2015
    Publication date: July 30, 2015
    Inventor: Giovanni Monteleone
  • Methods of Monitoring Responsiveness to Anti-SMAD7 Therapy
    Publication number: 20150148245
    Abstract: Methods for monitoring whether a subject will be sensitive or resistant to treatment with an anti-SMAD7 therapy are disclosed. The methods are based on the determining of the amount of CCR9+ FOXP3+ T cells, CCR9+ IFN-gamma+ T cells, CCR9+ IL17A+ T cells, FOXP3+ T cells, IFN-gamma+ T cells, and/or IL17A+ T cells in a sample from the subject. Measurement of T cell populations may be determined by flow cytometry, immunohistochemistry, and/or ELISA.
    Type: Application
    Filed: September 14, 2012
    Publication date: May 28, 2015
    Applicant: Nogra Pharma Limited
    Inventors: Giovanni Monteleone, Francesca Viti, Salvatore Bellinvia
  • Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field
    Patent number: 9006418
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: April 14, 2015
    Assignee: Nogra Pharma Limited
    Inventor: Giovanni Monteleone
  • Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field
    Patent number: 8907078
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: December 9, 2014
    Assignee: Nogra Pharma Limited
    Inventor: Giovanni Monteleone
  • Methods of Treating Colorectal Cancer
    Publication number: 20140271860
    Abstract: Disclosed herein are methods for treating/and or preventing colorectal cancer using a specific inhibitor of SMAD7 expression or function. Also disclosed are pharmaceutical compositions containing an inhibitor of SMAD7 for treating and/or preventing colorectal cancer and manufacture of medicaments containing an inhibitor of SMAD7 to be used in treating and/or preventing colorectal cancer.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: Nogra Pharma Limited
    Inventors: Giovanni Monteleone, Salvatore Bellinvia, Francesca Viti
  • Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field
    Publication number: 20140256788
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: April 30, 2014
    Publication date: September 11, 2014
    Applicant: NOGRA PHARMA LIMITED
    Inventor: Giovanni Monteleone
  • Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field
    Publication number: 20140142163
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: December 30, 2013
    Publication date: May 22, 2014
    Applicant: Nogra Pharma Limited
    Inventor: Giovanni Monteleone
  • Antisense oligonucleotides (ODN) against SMAD7 and uses thereof in medical field
    Patent number: 8648186
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: February 11, 2014
    Assignee: Nogra Pharma Limited
    Inventor: Giovanni Monteleone
  • Methods for preventing or reducing colon carcinogenesis
    Patent number: 8501806
    Abstract: The present invention is directed in part to methods of preventing or reducing colon carcinogenesis comprising administering to a patient at risk of colorectal cancer, a pharmaceutical preparation comprising a chemopreventive agent disclosed herein.
    Type: Grant
    Filed: December 3, 2009
    Date of Patent: August 6, 2013
    Assignee: Nogra Pharma Limited
    Inventors: Sergio Baroni, Salvatore Bellinvia, Francesca Viti, Giovanni Monteleone
  • ANTISENSE OLIGONUCLEOTIDES (ODN) AGAINST SMAD7 AND USES THEREOF IN MEDICAL FIELD
    Publication number: 20120136043
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: December 20, 2011
    Publication date: May 31, 2012
    Inventor: Giovanni Monteleone
  • Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field
    Patent number: 8106182
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: January 31, 2012
    Assignee: Giuliani International Limited
    Inventor: Giovanni Monteleone
  • Methods for Preventing or Reducing Colon Carcinogenesis
    Publication number: 20110288177
    Abstract: The present invention is directed in part to methods of preventing or reducing colon carcinogenesis comprising administering to a patient at risk of colorectal cancer, a pharmaceutical preparation comprising a chemopreventive agent disclosed herein.
    Type: Application
    Filed: December 3, 2009
    Publication date: November 24, 2011
    Inventors: Sergio Baroni, Salvatore Bellinvia, Francesca Viti, Giovanni Monteleone
  • Antisense Oligonucleotides (ODN) Against SMAD7 and Uses Thereof in Medical Field
    Publication number: 20100317719
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: August 11, 2010
    Publication date: December 16, 2010
    Inventor: Giovanni Monteleone
  • Antisense oligonucleotides (ODN) against Smad7 and uses thereof in medical field
    Patent number: 7807818
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: November 3, 2008
    Date of Patent: October 5, 2010
    Assignee: Giuliani International Limited
    Inventor: Giovanni Monteleone
  • Antisense oligonucleotides (ODN) against Smad7 and uses in medical field thereof
    Patent number: 7700757
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Grant
    Filed: March 8, 2004
    Date of Patent: April 20, 2010
    Assignee: Giuliani Internaitonal Limited
    Inventor: Giovanni Monteleone
  • Antigenic Epitopes Of Inteleukin-21, Related Antibodies And Their Use In Medical Field
    Publication number: 20090214549
    Abstract: The present invention relates to antigenic epitopes of interleukin-21, related antibodies and their use in medical field, in particular for the treatment of immune-inflammatory diseases characterized by an enhanced production and/or activity of IL-21, such as for example chronic inflammatory bowel diseases (IBD), celiac disease and psoriasis.
    Type: Application
    Filed: November 24, 2005
    Publication date: August 27, 2009
    Inventor: Giovanni Monteleone
  • ANTISENSE OLIGONUCLEOTIDES (ODN) AGAINST SMAD7 AND USES THEREOF IN MEDICAL FIELD
    Publication number: 20090156539
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: November 3, 2008
    Publication date: June 18, 2009
    Inventor: Giovanni Monteleone
  • Antisense oligonucleotides (odn) against smad7 and uses in medical field thereof
    Publication number: 20070167385
    Abstract: The invention relates to antisense oligonucleotidic sequences (ODN) against Smad7 suitably modified, and their uses in medical field as therapeutic biological agents, in particular in the treatment of chronic inflammatory bowel disease, such as Crohn's disease and ulcerative colitis.
    Type: Application
    Filed: March 8, 2004
    Publication date: July 19, 2007
    Inventor: Giovanni Monteleone