Patents by Inventor Giovanni Neri

Giovanni Neri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODY COMPOSITIONS
    Publication number: 20230165960
    Abstract: This invention relates to stable formulations that can be prepared to high concentration of active agent using low amounts of detergents and to methods for producing such formulations. In particular, this invention relates to formulations containing the L19-TNF? immunocytokine.
    Type: Application
    Filed: May 25, 2022
    Publication date: June 1, 2023
    Applicant: Philogen S.p.A.
    Inventors: Giovanni Neri, Camilla Bacci
  • Antibody compositions
    Patent number: 11351257
    Abstract: This invention relates to stable formulations that can be prepared to high concentration of active agent using low amounts of detergents and to methods for producing such formulations. In particular, this invention relates to formulations containing the L19-TNF? immunocytokine.
    Type: Grant
    Filed: July 14, 2017
    Date of Patent: June 7, 2022
    Assignee: PHILOGEN S.P.A.
    Inventors: Giovanni Neri, Camilla Bacci
  • Antibody Compositions
    Publication number: 20210093720
    Abstract: This invention relates to stable formulations that can be prepared to high concentration of active agent using low amounts of detergents and to methods for producing such formulations. In particular, this invention relates to formulations containing the L19-TNF? immunocytokine.
    Type: Application
    Filed: June 14, 2017
    Publication date: April 1, 2021
    Inventors: Giovanni Neri, Camilla Bacci
  • IMMUNOCYTOKINES WITH PROGRESSIVE ACTIVATION MECHANISM
    Publication number: 20190351024
    Abstract: The present invention relates to a combination comprising at least an immunocytokine comprising at least a primary binding protein or peptide and a cytokine, fused or conjugated to one another, and a secondary binding molecule capable of binding to at least a section of at least one cytokine comprised in the immunocytokine.
    Type: Application
    Filed: December 21, 2017
    Publication date: November 21, 2019
    Inventors: Giovanni Neri, Alessandra Villa, Florent Samain, Martina Bigatti
  • Anti-ED-A immunoconjugates for inflammatory bowel disease
    Patent number: 10239939
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: March 26, 2019
    Assignee: PHILOGEN S.P.A.
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'hara, Jianqing Chen
  • Antigen associated with the neovasculature of tumour metastases
    Patent number: 9896503
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumour metastases.
    Type: Grant
    Filed: October 5, 2015
    Date of Patent: February 20, 2018
    Assignee: Philogen S.P.A.
    Inventors: Jascha-Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • ANTIGENS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE
    Publication number: 20180044408
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Application
    Filed: June 1, 2017
    Publication date: February 15, 2018
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'hara, Jianqing Chen
  • Anti-ED-A immunoconjugates for inflammatory bowel disease
    Patent number: 9695232
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Grant
    Filed: October 3, 2012
    Date of Patent: July 4, 2017
    Assignee: Philogen S.p.A.
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'Hara, Jianqing Chen
  • NOVEL ANTIGEN ASSOCIATED WITH THE NEOVASCULATURE OF TUMOUR METASTASES
    Publication number: 20160083461
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumour metastases.
    Type: Application
    Filed: October 5, 2015
    Publication date: March 24, 2016
    Applicant: PHILOGEN S.P.A.
    Inventors: Jascha-Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • ANTIGENS ASSOCIATED WITH INFLAMMATORY BOWEL DISEASE
    Publication number: 20150361161
    Abstract: Specific binding members that bind the ED-A isoform of fibronectin for use in methods of treatment, diagnosis, detection and/or imaging of inflammatory bowel disease (IBD), and/or for use in delivery to the IBD tissue of a molecule conjugated to the specific binding member. The specific binding member may, for example, be conjugated to an immunosupressive or anti-inflammatory molecule, such as interleukin-10.
    Type: Application
    Filed: October 3, 2012
    Publication date: December 17, 2015
    Inventors: Giovanni Neri, Kathrin Schwager, Melanie C. Ruzek, Denise M. O'Hara, Jianqing Chen
  • Antigen associated with the neovasculature of tumour metastases
    Patent number: 9181347
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumor metastases.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: November 10, 2015
    Assignee: Philogen S.p.A.
    Inventors: Jascha-Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • ANTIBODIES OF THE ED-B DOMAIN OF FIBRONECTIN, THEIR CONSTRUCTION AND USES
    Publication number: 20140134182
    Abstract: According to the present invention there is provided a specific binding member which is specific for and binds directly to the ED-B oncofoetal domain of fibronectin (FN). The invention also provides materials and methods for the production of such binding members.
    Type: Application
    Filed: October 4, 2013
    Publication date: May 15, 2014
    Applicant: PHILOGEN S.P.A.
    Inventors: Dario NERI, Barbara CARNEMOLLA, Annalisa SIRI, Enrica BALZA, Patrizia CASTELLANI, Luciano ZARDI, Gregory Paul WINTER, Giovanni NERI, Laura BORSI, Alessandro PINI
  • NOVEL ANTIGEN ASSOCIATED WITH THE NEOVASCULATURE OF TUMOUR METASTASES
    Publication number: 20130280759
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumour metastases.
    Type: Application
    Filed: July 3, 2013
    Publication date: October 24, 2013
    Inventors: Jascha-Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • NOVEL ANTIGEN ASSOCIATED WITH THE NEOVASCULATURE OF TUMOUR METASTASES
    Publication number: 20130266511
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumour metastases.
    Type: Application
    Filed: June 6, 2013
    Publication date: October 10, 2013
    Inventors: Jascha-Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • Antigen associated with the neovasculature of tumour metastases
    Patent number: 8481684
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumour metastases.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: July 9, 2013
    Assignee: Philogen S.p.A.
    Inventors: Jascha-Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • NOVEL ANTIGEN ASSOCIATED WITH THE NEOVASCULATURE OF TUMOUR METASTASES
    Publication number: 20130040361
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumour metastases.
    Type: Application
    Filed: August 9, 2012
    Publication date: February 14, 2013
    Inventors: Jascha-Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • Antigen associated with the neovasculature of tumour metastases
    Patent number: 8263041
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumor metastases.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: September 11, 2012
    Assignee: Philogen, S.p.A.
    Inventors: Jascha Nikolai Rybak, Christoph Rosli, Alessandra Villa, Giovanni Neri, Dario Neri
  • MOLECULAR MARKERS FOR AUTISM
    Publication number: 20110079076
    Abstract: The invention relates to the determination of phosphorylation levels of some specific salivary peptides (statherin, histatin 1, acidic proline-rich proteins, both in whole form (PRP-1 type) and in truncated form (PRP-3 type) as a non-invasive diagnostic marker with a >40% sensitivity for defining autism spectrum disorders (ASDs) patients, methods for performing said determination, a kit for the non-invasive diagnosis of at least 40% of autism cases, containing means for such a determination, and the use of such a determination for therapeutical research on autism.
    Type: Application
    Filed: June 8, 2009
    Publication date: April 7, 2011
    Inventors: Massimo Castagnola, Irene Messana, Rosanna Inzitari, Chiara Fanali, Tiziana Cabras, Fiorella Gurrieri, Maria Giulia Torrioli, Giovanni Neri
  • NOVEL ANTIGEN ASSOCIATED WITH THE NEOVASCULATURE OF TUMOUR METASTASES
    Publication number: 20100247541
    Abstract: The invention relates to a binding member that binds the Extra Domain-A (ED-A) isoform of fibronectin for the treatment of tumour metastases.
    Type: Application
    Filed: March 31, 2008
    Publication date: September 30, 2010
    Inventors: Jascha-Nikolai Rybak, Christoph Rösli, Alessandra Villa, Giovanni Neri, Dario Neri
  • ANTIBODIES OF THE ED-B DOMAIN OF FIBRONECTIN, THEIR CONSTRUCTION AND USES
    Publication number: 20080274099
    Abstract: According to the present invention there is provided a specific binding member which is specific for and binds directly to the ED-B oncofoetal domain of fibronectin (FN). The invention also provides materials and methods for the production of such binding members.
    Type: Application
    Filed: August 21, 2007
    Publication date: November 6, 2008
    Inventors: Dario Neri, Barbara Carnemolla, Enrica Balza, Patrizia Castellani, Luciano Zardi, Gregory Paul Winter, Giovanni Neri, Laura Borsi, Alessandro Pini