Patents by Inventor Giovanni Rivolta

Giovanni Rivolta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a sulfated derivative of 3,5-diiodo-o-[3-iodophenyl]-l-tyrosine
    Patent number: 10457635
    Abstract: The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L-tyrosine (T3S) by starting from the corresponding phenolic compound, in the presence of chlorosulfonic acid and dimethylacetamide as a solvent. The so obtained T3S compound may conveniently be isolated in a pure form as a solid in good yields. The present invention further relates to the process for T3S preparation, wherein the starting reagent is T2 and further comprising the formulation of such compound in tablets. Furthermore, the invention discloses non-radioactive immunoassays based on T3S derivatives.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: October 29, 2019
    Assignee: BRACCO IMAGING S.p.A.
    Inventors: Pier Lucio Anelli, Maria Argese, Valeria Boi, Livio Cavalieri, Laura Galimberti, Sonia Gazzetto, Luciano Lattuada, Federico Maisano, Giovanni Rivolta, Fulvia Vella
  • 3,5,3?-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof
    Patent number: 10238615
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: March 26, 2019
    Assignee: Bracco S.P.A.
    Inventors: Livio Cavalieri, Giovanni Rivolta, Fulvia Vella
  • Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine
    Publication number: 20180118669
    Abstract: The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L-tyrosine (T3S) by starting from the corresponding phenolic compound, in the presence of chlorosulfonic acid and dimethylacetamide as a solvent. The so obtained T3S compound may conveniently be isolated in a pure form as a solid in good yields. The present invention further relates to the process for T3S preparation, wherein the starting reagent is T2 and further comprising the formulation of such compound in tablets. Furthermore, the invention discloses non-radioactive immunoassays based on T3S derivatives.
    Type: Application
    Filed: December 22, 2017
    Publication date: May 3, 2018
    Applicant: BRACCO IMAGING S.p.A.
    Inventors: Pier Lucio ANELLI, Maria ARGESE, Valeria BOI, Livio CAVALIERI, Laura GALIMBERTI, Sonia GAZZETTO, Luciano LATTUADA, Federico MAISANO, Giovanni RIVOLTA, Fulvia VELLA
  • 3,5,3'-TRIIODOTHYRONINE SULFATE AS THYROMIMETIC AGENT AND PHARMACEUTICAL FORMULATIONS THEREOF
    Publication number: 20170007563
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Application
    Filed: September 21, 2016
    Publication date: January 12, 2017
    Applicant: Bracco S.P.A.
    Inventors: Livio Cavalieri, Giovanni Rivolta, Fulvia Vella
  • 3,5,3?-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof
    Patent number: 9468619
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: October 18, 2016
    Assignee: Bracco S.P.A.
    Inventors: Aldo Pinchera, Livio Cavalieri, Federico Maisano, Giovanni Rivolta, Ferruccio Santini, Fulvia Vella
  • 3,5,3?-triiodothyronine sulfate as thyromimetic agent and pharmaceutical formulations thereof
    Patent number: 9439883
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: September 13, 2016
    Assignee: Bracco S.P.A.
    Inventors: Aldo Pinchera, Livio Cavalieri, Federico Maisano, Giovanni Rivolta, Ferruccio Santini, Fulvia Vella
  • Process For The Preparation Of A Sulfated Derivative Of 3,5-Diiodo-O-[3-Iodophenyl]-L-Tyrosine
    Publication number: 20140024717
    Abstract: The present invention relates to a process for the preparation of the mono sodium salt of the derivative 3,5-diiodo-O-[3-iodo-4-(sulphooxy)phenyl]-L-tyrosine (T3S) by starting from the corresponding phenolic compound, in the presence of chloro-sulfonic acid and dimethylacetamide as a solvent. The so obtained T3S compound may conveniently be isolated in a pure form as a solid in good yields. The present invention further relates to the process for T3S preparation, wherein the starting reagent is T2 and further comprising the formulation of such compound in tablets. Furthermore, the invention discloses non-radioactive immunoassays based on T3S derivatives.
    Type: Application
    Filed: April 5, 2012
    Publication date: January 23, 2014
    Applicant: BRACCO IMAGING S.p.A.
    Inventors: Pier Lucio Anelli, Maria Argese, Luciano Lattuada, Federico Maisano, Sonia Gazzetto, Laura Galimberti, Valeria Boi, Giovanni Rivolta, Livio Cavalieri, Fulvia Vella
  • 3,5,3'-Triiodothyronine Sulfate As Thyromimetic Agent And Pharmaceutical Formulations Thereof
    Publication number: 20130281536
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Application
    Filed: June 13, 2013
    Publication date: October 24, 2013
    Inventors: Aldo PINCHERA, Livio CAVALIERI, Federico MAISANO, Giovanni RIVOLTA, Ferruccio SANTINI, Fulvia VELLA
  • 3,5,3'-TRIIODOTHYRONINE SULFATE AS THYROMIMETIC AGENT AND PHARMACEUTICAL FORMULATIONS THEREOF
    Publication number: 20110245342
    Abstract: The invention regards the use of triiodothyronine sulfate, commonly named T3S, as a medicament having thyromimetic activity for the treatment of pathologies due to organic deficiency of triiodothyronine (T3), as such or in association with thyroxine (T4), and pharmaceutical formulations for oral administration thereof.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 6, 2011
    Applicant: Bracco S.p.A.
    Inventors: Aldo PINCHERA, Ferruccio Santini, Giovanni Rivolta, Livio Cavalieri, Fulvia Vella, Federico Maisano