Patents by Inventor Girija GOYAL

Girija GOYAL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human lymphoid tissue-on-chip
    Patent number: 11865536
    Abstract: An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: January 9, 2024
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Girija Goyal, Donald E. Ingber
  • HUMAN LYMPHOID TISSUE-ON-CHIP
    Publication number: 20230356216
    Abstract: An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels.
    Type: Application
    Filed: June 30, 2023
    Publication date: November 9, 2023
    Inventors: Girija Goyal, Donald E. Ingber
  • HUMAN LYMPHOID TISSUE-ON-CHIP
    Publication number: 20220250055
    Abstract: An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels.
    Type: Application
    Filed: April 27, 2022
    Publication date: August 11, 2022
    Inventors: Girija Goyal, Donald E. Ingber
  • Human lymphoid tissue-on-chip
    Patent number: 11406975
    Abstract: An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: August 9, 2022
    Assignee: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Girija Goyal, Donald E. Ingber
  • HUMAN IN VITRO ORTHOTOPIC AND METASTATIC MODELS OF CANCER
    Publication number: 20200270557
    Abstract: Disclosed herein are devices and methods for generating orthotopic models of cancer. The devices and methods include providing a microfluidic device having a body, the body including a first microchannel separated from a second microchannel by an at least partially porous membrane, the membrane having a first side facing the first microchannel and a second side facing the second microchannel, seeding the first side of the membrane with healthy cells and cancer cells such that the cancer cells are seeded with a differentiated tissue layer, and culturing the healthy cells and the cancer cells within the microfluidic device by flowing medium through one or more of the first and second microchannels with or without endothelium in the second channel.
    Type: Application
    Filed: September 18, 2018
    Publication date: August 27, 2020
    Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Girija GOYAL, Bryan HASSELL, Donald E. Ingber
  • HUMAN LYMPHOID TISSUE-ON-CHIP
    Publication number: 20190232277
    Abstract: An organ-on-a-chip microfluidic device is disclosed that mimics a human lymph node and/or human lymphoid tissue. The device can include cells from human blood and lymphatic tissue, include an extracellular matrix for the development of immune system components, and provide for the perfusion of fluids and solids resembling blood and lymphatic fluid within micrometer sized channels.
    Type: Application
    Filed: July 18, 2017
    Publication date: August 1, 2019
    Inventors: Girija Goyal, Donald E. Ingber
  • METHODS OF TREATING CANCER
    Publication number: 20180228775
    Abstract: The present invention provides methods of treating cancer.
    Type: Application
    Filed: September 8, 2015
    Publication date: August 16, 2018
    Inventors: Girija GOYAL, Glenn DRANOFF