Abstract: Devices having male connectors for preventing connection to non-compatible female connectors are described. An exemplary male connector includes an elongate tip and a collar disposed coaxially around the elongate tip including a plurality of ribs disposed on either an inside surface or an outside surface of the collar for preventing entry of a non-compatible female connector into a channel formed between the elongate tip and the collar. One or more embodiments pertain to a device with a male connector and a compatible female connector including a threaded portion for engaging a corresponding threaded portion of the male connector.

Abstract: Flush syringe assemblies capable of creating pulsatile movement of the plunger rod as it moves in the distal direction within a syringe barrel, while preventing overpressurization of the cathether are provided. An exemplary flush syringe assembly includes a syringe barrel with a first pulsing element and a chamber with flush solution, a plunger rod with a stopper and a second pulsing element that interacts with the first pulsing element to provide an engagement force that causes pulsatile movement of the plunger rod and a thumb press slidably attached to the plunger rod with a pulse control element. The pulse control element is compressible to create a compression force that is greater than the engagement force of the first pulsing element and the second pulsing element.

Abstract: Syringe assemblies for use in flush applications are provided. Syringe assemblies according to one aspect of the present invention include a plunger rod and a syringe barrel that incorporate one or more pulsing elements on the plunger rod or barrel that are rotatable to create pulsatile movement or continuous and unimpeded movement a plunger rod within a syringe barrel. One or more embodiments pertain to syringe assemblies permit both pulsatile movement of the plunger rod within the barrel and continuous and unimpeded movement of the plunger rod in the distal direction along substantially the entire length of the syringe barrel upon application of force to the plunger rod in only the distal direction. Methods of flushing a catheter are also provided.