Abstract: The present disclosure provides the use of Lactobacillus paracasei ET-22 in enhancing resistance of the intestinal tract to bacterial infection and improving intestinal immunity. Particularly, the present disclosure provides the use of a Lactobacillus paracasei in the preparation of a composition for improving intestinal immunity, wherein the Lactobacillus paracasei has a deposit number of CGMCC 15077. The present inventors have discovered that this bacteria strain alone can significantly improve the resistance of the intestinal tract to bacterial infection, combat invasion by pathogenic bacteria in the intestinal system, maintain the intestinal barrier function, and/or prevent diarrhea caused by pathogenic bacteria.

Abstract: The present disclosure provides a composition comprising Bifidobacterium lactis and human milk oligosaccharides (HMOs) and use thereof. The composition is capable of effectively enhancing resistance of an organism to Staphylococcus aureus infection, improving innate immunity of an organism, and/or anti-aging, and can be added to various health foods and healthcare foods.

Abstract: The present disclosure provides novel uses of Bifidobacterium lactis BL-99 in anti-aging and improving innate immunity. The Bifidobacterium lactis strain according to the present disclosure has a deposit number of CGMCC 15650. It is discovered in the present disclosure that this strain alone has an anti-aging effect, is capable of improving innate immunity of an organism, and is capable of enhancing resistance of an organism to Staphylococcus aureus infection, thereby providing use of the Bifidobacterium lactis strain of deposit number CGMCC 15650 in preparation of a composition having an anti-aging effect, capable of improving innate immunity of an organism, and/or capable of enhancing resistance of an organism to Staphylococcus aureus infection.

Abstract: The present invention relates to the field of food and pharmaceutical products, and specifically to human milk oligosaccharide for improving resistance of organism against Staphylococcus aureus infection. In particular, the present invention relates to use of human milk oligosaccharide in preparation of a nutritional composition or medicament for prevention and/or treatment of diseases associated with Staphylococcus aureus infection in individuals, or for alleviation of discomfort associated with Staphylococcus aureus infection, or for improvement of an individual's resistance against Staphylococcus aureus infection, or for improvement of an individual's innate immunity and/or anti-aging.