Patents by Inventor Gisela M. Ferreira

Gisela M. Ferreira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein purification using HCIC and ion exchange chromatography
    Patent number: 8697847
    Abstract: The present invention provides methods for purifying proteins. In particular, the methods employ a two-step non-affinity chromatography process without the use of an in-process tangential flow filtration step.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: April 15, 2014
    Assignee: Medarex, L.L.C.
    Inventors: Alahari Arunakumari, Gisela M. Ferreira
  • Protein purification by citrate precipitation
    Patent number: 8063189
    Abstract: The invention provides methods for isolating proteins in purified form from mixtures by precipitation with citrate. The methods are advantageous in that they effectively separate a protein from lower molecular weight contaminants, including fragments or portions of the protein. Such methods are particularly useful for purifying antibodies from mixtures containing antibody proteolytic fragments and unpaired chains.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: November 22, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Alahari Arunakumari, Gisela M. Ferreira
  • PROTEIN PURIFICATION BY CITRATE PRECIPITATION
    Publication number: 20100261886
    Abstract: The invention provides methods for isolating proteins in purified form from mixtures by precipitation with citrate. The methods are advantageous in that they effectively separate a protein from lower molecular weight contaminants, including fragments or portions of the protein. Such methods are particularly useful for purifying antibodies from mixtures containing antibody proteolytic fragments and unpaired chains.
    Type: Application
    Filed: April 13, 2010
    Publication date: October 14, 2010
    Applicant: Bristol-Myers Squibb Company
    Inventors: Alahari Arunakumari, Gisela M. Ferreira