Abstract: Compounds having analgesic activity are disclosed which have the general formula: ##STR1## wherein R.sub.1 is hydrogen, alkyl having 1 to 4 carbon atoms, cyclohexyl or benzyl; R is selected from the group consisting of alkyl having at least 4 carbon atoms; cyclohexyl; unsubstituted phenyl or phenyl substituted with one or more halogen atoms, methyl, methoxy, hydroxy, cyano, nitro, trifluoromethyl, carboxyl, ethoxycarbonyl, acetamido, methylsulfonyl, phenoxy, benzoyl, phenyl, .alpha.-hydroxybenzyl, cyclohexyl or carbamoyl; thienyl; pyridyl; naphthyl; naphthyl substituted with methoxy; adamantyl; and benzyl; and n is 1, 2 or 3, with the provisos that (1) when R is carboxyphenyl, benzoylphenyl, or (.alpha.-hydroxybenzyl) phenyl, n is not 3, and (2) when R is (.alpha.-hydroxy benzyl) phenyl, R.sub.1 is not benzyl, and acid addition salts thereof.

Abstract: Derivatives of 5H-furanone-2 and 3H-dihydrofuranone-2, substituted at the 3 position with substituted phenyl and at the 5 position with substituted methyl, are prepared by various processes. The derivatives are inhibitors of monoamine oxidase and are useful for treating depression.

Abstract: Derivatives of 5H-furanone-2 and 3H-dihydrofuranone-2, substituted at the 3 position with substituted phenyl and at the 5 position with substituted methyl, are prepared by various processes. The derivatives are inhibitors of monoamine oxidase and are useful for treating depression.

Abstract: There are disclosed 3-substituted phenyl-5-hydroxymethyl oxazolidinones which possess anti-depressant properties. The compounds are prepared by cyclizing, with ethyl carbonate, 1-substituted phenylamino-2,3-propanediol compounds.

Abstract: There are disclosed 3-substituted phenyl-5-hydroxymethyl oxazolidinones which possess anti-depressant properties. The compounds are prepared by cyclizing, with ethyl carbonate, 1-substituted phenylamino-2,3-propanediol compounds.

Abstract: Compounds having the formula ##STR1## wherein R.sub.1 is hydrogen or CONHR.sub.7 and R.sub.7 is methyl or isopropyl,And whereinWhen R.sub.1 is hydrogen: R is p-nitro, p-cyano; p-aldehydo; p-acetyl; m-ethyl; m-nitro; m-bromo; 3,4-dimethyl; m-NH.sub.2 ; p-methylamino; p-dimethylamino; p-diethylamino; p-methylbenzylamino; p-pyrrolidino; p-piperidino; SR.sub.4 in para position in which R.sub.4 is alkyl having 1 to 4 carbon atoms or cyclohexyl; OR.sub.5 is para position in which R.sub.5 is alkyl having 2 to 7 carbon atoms, cyclohexyl, cyclohexylmethyl, acetylmethyl; cyanomethyl, alkene-2 yl having 3 to 5 carbon atoms, butene-3 yl, cyclohexene-1 methyl, propargyl, butyne-2 yl, ##STR2## in which n is one or 2 and when n is one, R.sub.6 is hydrogen, o-fluoro, o-methyl, m-chloro, m-fluoro, m-methyl, m-trifluoromethyl, p-chloro, p-bromo-, p-fluoro, p-cyano, p-nitro or p-dimethylamino and when n is 2, R.sub.6 is hydrogen; and 3-methyl-4-benzyloxy:When R.sub.1 is CONHR.sub.7 and R.sub.