Abstract: Disclosed herein is a method for generating capsules with a hydrogel matrix. The method includes the steps: providing in a first chamber a dispersed aqueous phase, the dispersed aqueous phase including water and a hydrogel matrix-forming agent, in which the hydrogel matrix-forming agent is configured to form a hydrogel matrix upon exposure to a gelation inducer; providing in a second chamber a continuous oil phase, the continuous oil phase including oil and at least one first surfactant. The first and second chambers are fluidic connected by one or more channels, preferably by micro-channels. The method further includes: guiding the dispersed aqueous phase from the first chamber through the one or more channels into the second chamber to form an emulsion or dispersion of the dispersed aqueous phase in the continuous oil phase and exposing the hydrogel matrix-forming agent to a gelation inducer to form capsules with a hydrogel matrix.

Abstract: Disclosed herein is a method for generating capsules with a solid matrix (7) as well as a capsule assembly comprising a plurality of capsules obtained by such a method. The method relies on temperature dependent step-emulsification of a droplet phase including a liquid hydrophobic matrix and a continuous aqueous phase.

Abstract: Disclosed herein is a method for generating capsules with a hydrogel matrix. The method includes the steps: providing in a first chamber a dispersed aqueous phase, the dispersed aqueous phase including water and a hydrogel matrix-forming agent, in which the hydrogel matrix-forming agent is configured to form a hydrogel matrix upon exposure to a gelation inducer; providing in a second chamber a continuous oil phase, the continuous oil phase including oil and at least one first surfactant. The first and second chambers are fluidic connected by one or more channels, preferably by micro-channels. The method further includes: guiding the dispersed aqueous phase from the first chamber through the one or more channels into the second chamber to form an emulsion or dispersion of the dispersed aqueous phase in the continuous oil phase and exposing the hydrogel matrix-forming agent to a gelation inducer to form capsules with a hydrogel matrix.

Abstract: Disclosed is a method for generating capsules with a matrix shell encasing an oil core. The method includes: providing in a first chamber a core-forming emulsion of an aqueous dispersed phase in an oil phase including water and a dissolved gelation-inducing agent, and a first surfactant; providing in a second chamber a second aqueous solution including water and a second surfactant; wherein the first chamber and the second chamber are fluidically connected by one or more channels; guiding the core-forming emulsion from the first chamber through the channel(s) into the second chamber to form a dispersion of the core-forming emulsion in the aqueous solution; mixing the dispersion with an aqueous shell-forming solution including water and a water soluble matrix-forming agent; and reacting the gelation-inducing agent and the matrix-forming agent in the formed dispersion to form capsules of a water insoluble matrix shell encasing an oil core.