Patents by Inventor Giulia Castellani

Giulia Castellani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for CNS Disease Modification
    Publication number: 20220146534
    Abstract: A method for predicting whether a patient diagnosed with a disease, disorder, condition or injury of the CNS is likely to be responsive or non-responsive to treatment with an immune checkpoint modulator is provided, wherein said method comprises determining ex vivo, in a blood sample obtained from the patient, or in a fraction thereof, a biomarker selected from: (a) the level of a monocyte subpopulation expressing CCR2, CD204 or a combination thereof, or CCR2 and a marker selected from igf1, lyve1, Stab-1, Siglec1 and Mrc1, or any combination thereof, (b) the ratio of the level of a monocyte subpopulation (CD14+ cells) expressing CCR2highCX3CR1low to a monocyte subpopulation expressing CCR2lowCX3CR1high; (c) the level of a CCR2 agonist; and (d) the level of a CCR2 antagonist.
    Type: Application
    Filed: January 16, 2020
    Publication date: May 12, 2022
    Applicant: Yeda Research and Development, Co., Ltd.
    Inventors: Michal Eisenbach-Schwartz, Hila Ben-Yehuda, Michal Arad, Tommaso Croese, Javier Maria Peralta Ramos, Giulia Castellani, Neta Rosenzweig
  • RUBBER-REINFORCED VINYL AROMATIC (CO)POLYMER, HAVING AN OPTIMUM BALANCE OF PHYSICO-MECHANICAL PROPERTIES AND A HIGH GLOSS
    Publication number: 20120289660
    Abstract: Vinyl aromatic (co) polymer reinforced with a rubber selected from a linear diene rubber (i) with a solution viscosity lower than 70 cPs; a partially radial diene rubber (ii), with a solution viscosity lower than 70 cPs; a three-chain diene rubber (iii) with a solution viscosity lower than 70 cPs; a blend of linear diene rubbers (i) and radial diene rubbers (iv) in a maximum ratio between them (i)/(iv) of between 99.5/0.5 and 85/15.
    Type: Application
    Filed: December 10, 2009
    Publication date: November 15, 2012
    Applicant: POLIMERI EUROPA S.p.A.
    Inventors: Alessandro Casalini, Leonardo Chiezzi, Anna Grazia Rossi, Leonardo Castellani, Giulia Castellani, Luca Soddu