Patents by Inventor Giuliano Bensi

Giuliano Bensi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic compositions for
    Patent number: 9056912
    Abstract: The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40, GAS 389, GAS 504, GAS 509, GAS 366, GAS 159, GAS 217, GAS 309, GAS 372, GAS 039, GAS 042, GAS 058, GAS 290, GAS 511, GAS 533, GAS 527, GAS 294, GAS 253, GAS 529, GAS 045, GAS 095, GAS 193, GAS 137, GAS 084, GAS 384, GAS 202, and GAS 057.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: June 16, 2015
    Assignee: Novartis Vaccines and Diagnostics, SRL
    Inventors: Guido Grandi, John Telford, Giuliano Bensi
  • COMBINATION GAS VACCINES AND THERAPEUTICS
    Publication number: 20150132337
    Abstract: Compositions useful for reducing the risk of, preventing, and/or treating S. pyogenes (GAS) infections which comprise combinations of GAS antigens, nucleic acid molecules encoding the antigens, or antibodies which specifically bind to the antigens.
    Type: Application
    Filed: November 13, 2014
    Publication date: May 14, 2015
    Inventors: Guido GRANDI, Immaculada MARGARIT Y ROS, Sabrina CAPO, Giuliano BENSI, Andrea Guido Oreste MANETTI
  • METHOD FOR PRODUCING YEAST EXPRESSED HPV TYPES 6 AND 16 CAPSID PROTEINS
    Publication number: 20140099719
    Abstract: Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production of conformational antibodies against both L1 proteins upon administration to mice.
    Type: Application
    Filed: May 14, 2013
    Publication date: April 10, 2014
    Applicant: Novartis Vaccines and Diagnostics, Inc.
    Inventors: Daniela Tornese Buonamassa, Catherine E. Greer, Cesira L. Galeotti, Giuliano Bensi, Roberto Petracca
  • IMMUNOGENIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES
    Publication number: 20140037671
    Abstract: The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40, GAS 389, GAS 504, GAS 509, GAS 366, GAS 159, GAS 217, GAS 309, GAS 372, GAS 039, GAS 042, GAS 058, GAS 290, GAS 511, GAS 533, GAS 527, GAS 294, GAS 253, GAS 529, GAS 045, GAS 095, GAS 193, GAS 137, GAS 084, GAS 384, GAS 202, and GAS 057.
    Type: Application
    Filed: September 9, 2013
    Publication date: February 6, 2014
    Applicant: NOVARTIS VACCINES AND DIAGNOSTICS, SRL
    Inventors: Guido Grandi, John Telford, Giuliano Bensi
  • Immunogenic compositions for
    Patent number: 8529913
    Abstract: The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40, GAS 389, GAS 504, GAS 509, GAS 366, GAS 159, GAS 217, GAS 309, GAS 372, GAS 039, GAS 042, GAS 058, GAS 290, GAS 511, GAS 533, GAS 527, GAS 294, GAS 253, GAS 529, GAS 045, GAS 095, GAS 193, GAS 137, GAS 084, GAS 384, GAS 202, and GAS 057.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: September 10, 2013
    Assignee: Novartis Vaccines and Diagnostics, SRL
    Inventors: Guido Grandi, John Telford, Giuliano Bensi
  • Mutant forms of streptolysin O
    Patent number: 8409589
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Grant
    Filed: September 14, 2011
    Date of Patent: April 2, 2013
    Assignee: Novartis AG
    Inventors: Giuliano Bensi, Immaculada Margarit Y Ros, Emiliano Chiarot, Guido Grandi, Maria Scarselli
  • IMMUNOGENIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES
    Publication number: 20120315292
    Abstract: The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40, GAS 389, GAS 504, GAS 509, GAS 366, GAS 159, GAS 217, GAS 309, GAS 372, GAS 039, GAS 042, GAS 058, GAS 290, GAS 511, GAS 533, GAS 527, GAS 294, GAS 253, GAS 529, GAS 045, GAS 095, GAS 193, GAS 137, GAS 084, GAS 384, GAS 202, and GAS 057.
    Type: Application
    Filed: March 2, 2012
    Publication date: December 13, 2012
    Applicant: NOVARTIS VACCINES AND DIAGNOSTICS, SRL
    Inventors: Guido Grandi, John Telford, Giuliano Bensi
  • IMMUNOGENIC AND THERAPEUTIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES
    Publication number: 20120107322
    Abstract: Compositions for preventing and/or treating S. pyogenes infection which comprise one or more active agents. The active agents are SLO antigens, nucleic acid molecules encoding the SLO antigens, and/or antibodies which selectively bind to the SLO antigens.
    Type: Application
    Filed: October 20, 2011
    Publication date: May 3, 2012
    Applicant: NOVARTIS AG
    Inventors: Maria SCARSELLI, Giuliano BENSI, Guido GRANDI
  • DIAGNOSIS OF NEUROPSYCHIATRIC AND BEHAVIOURAL DISORDERS
    Publication number: 20120088685
    Abstract: This invention provides a method of identifying GAS infection as the cause of a neuropsychiatric or behavioural disorder in a patient, or of identifying a patient at risk of developing a neuropsychiatric or behavioural disorder caused by GAS infection. This invention also provides associated protein arrays.
    Type: Application
    Filed: March 5, 2010
    Publication date: April 12, 2012
    Inventors: Graziella Orefici, Guido Grandi, Immaculada Margarity Ros, Renata Marie Grifantini, Giuliano Bensi, Mauro Bombaci
  • Immunogenic compositions for
    Patent number: 8128936
    Abstract: The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40, GAS 389, GAS 504, GAS 509, GAS 366, GAS 159, GAS 217, GAS 309, GAS 372, GAS 039, GAS 042, GAS 058, GAS 290, GAS 511, GAS 533, GAS 527, GAS 294, GAS 253, GAS 529, GAS 045, GAS 095, GAS 193, GAS 137, GAS 084, GAS 384, GAS 202, and GAS 057.
    Type: Grant
    Filed: March 2, 2010
    Date of Patent: March 6, 2012
    Assignee: Novartis Vaccines and Diagnostics, S.r.L.
    Inventors: Guido Grandi, John Telford, Giuliano Bensi
  • MUTANT FORMS OF STREPTOLYSIN O
    Publication number: 20120003258
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Application
    Filed: September 14, 2011
    Publication date: January 5, 2012
    Applicant: NOVARTIS AG
    Inventors: Giuliano BENSI, Immaculada MARGARIT Y ROS, Emiliano CHIAROT, Guido GRANDI, Maria SCARSELLI
  • Mutant forms of streptolysin O
    Patent number: 8039005
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Grant
    Filed: February 24, 2010
    Date of Patent: October 18, 2011
    Assignee: Novartis AG
    Inventors: Giuliano Bensi, Immaculada Margarit Y Ros, Emiliano Chiarot, Guido Grandi, Maria Scarselli
  • METHOD FOR PRODUCING YEAST EXPRESSED HPV TYPES 6 AND 16 CAPSID PROTEINS
    Publication number: 20110195506
    Abstract: Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production of conformational antibodies against both L1 proteins upon administration to mice.
    Type: Application
    Filed: January 12, 2011
    Publication date: August 11, 2011
    Inventors: Daniela Tornese BUONAMASSA, Catherine E. Greer, Cesira L. Galeotti, Giuliano Bensi, Roberto Petracca
  • Method for producing yeast expressed HPV types 6 and 16 capsid proteins
    Patent number: 7897155
    Abstract: Mosaic VLPs of viral capsid proteins from different virus types are described, as are methods of making the same. Specifically, a diploid yeast strain that coexpresses the L1 and L2 capsid proteins of both HPV-6 and HPV-16 as mosaic VLPs is described. The mosaic VLPs induced the production of conformational antibodies against both L1 proteins upon administration to mice.
    Type: Grant
    Filed: December 11, 2008
    Date of Patent: March 1, 2011
    Assignee: Novartis Vaccines & Diagnostics, Inc.
    Inventors: Daniela Tornese Buonamassa, Catherine E. Greer, Cesira L. Galeotti, Giuliano Bensi, Roberto Petracca
  • IMMUNOGENIC AND THERAPEUTIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES
    Publication number: 20110038879
    Abstract: Compositions for preventing and/or treating S. pyogenes infection which comprise one or more active agents. The active agents are SLO antigens, nucleic acid molecules encoding the SLO antigens, and/or antibodies which selectively bind to the SLO antigens.
    Type: Application
    Filed: October 30, 2007
    Publication date: February 17, 2011
    Applicant: NOVARTIS AG
    Inventors: Maria Scarselli, Giuliano Bensi, Guido Grandi
  • Immunogenic and therapeutic compositions for
    Patent number: 7838010
    Abstract: Group A streptococcal (GAS) antigens useful for providing immunity against pyogenes infection.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: November 23, 2010
    Assignee: Novartis Vaccines and Diagnostics S.R.L.
    Inventors: Giuliano Bensi, Guido Grandi, Nathalie Norais, Manuel J. Rodriguez Ortega
  • IMMUNOGENIC COMPOSITIONS FOR STREPTOCOCCUS PYOGENES
    Publication number: 20100221278
    Abstract: The invention includes a GAS antigen, GAS 40, which is particularly suitable for use either alone or in combinations with additional GAS antigens, such as GAS 117, GAS 130, GAS 277, GAS 236, GAS 40, GAS 389, GAS 504, GAS 509, GAS 366, GAS 159, GAS 217, GAS 309, GAS 372, GAS 039, GAS 042, GAS 058, GAS 290, GAS 511, GAS 533, GAS 527, GAS 294, GAS 253, GAS 529, GAS 045, GAS 095, GAS 193, GAS 137, GAS 084, GAS 384, GAS 202, and GAS 057.
    Type: Application
    Filed: March 2, 2010
    Publication date: September 2, 2010
    Applicant: NOVARTIS VACCINES AND DIAGNOSTICS, SRL
    Inventors: Guido Grandi, John Telford, Giuliano Bensi
  • Cytotoxic T-cell epitopes from
    Patent number: 7754228
    Abstract: Cytotoxic T-cell epitopes from C.pneumoniae proteins have been empirically determined. The epitopes from corresponding C.trachomatis proteins have also been identified, and some of these are identical to those from C.pneumoniae. The empirical method showed that algorithmic prediction was inadequate. The epitopes are useful for immunisation and/or diagnosis.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: July 13, 2010
    Assignee: Novartis Vaccines and Diagnostics, Srl
    Inventors: Giuliano Bensi, Guido Grandi, Sergio Abrignani
  • MUTANT FORMS OF STREPTOLYSIN O
    Publication number: 20100158935
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Application
    Filed: February 24, 2010
    Publication date: June 24, 2010
    Applicant: NOVARTIS AG
    Inventors: Giuliano BENSI, Immaculada MARGARIT Y ROS, Emiliano CHIAROT, Guido GRANDI, Maria SCARSELLI
  • Mutant forms of streptolysin O
    Patent number: 7731978
    Abstract: Forms of GAS25 (streptolysin O) which are not toxic but which still maintain the ability to induce protection against S. pyogenes are useful in vaccine compositions to induce protection against S. pyogenes.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: June 8, 2010
    Assignee: Novartis AG
    Inventors: Giuliano Bensi, Immaculada Margarit Y Ros, Emiliano Chiarot, Guido Grandi, Maria Scarselli