Patents by Inventor Giuliano Franchi

Giuliano Franchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anthracycline glycosides
    Patent number: 6187758
    Abstract: An anthracycline glycoside of formula I wherein R is one of the two following residues: or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: February 13, 2001
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Cinzia Portello, Emanuele Arlandini, Umberto Breme, Anna Luisa Colombo, Giuliano Franchi, Giuliano Oronzo, Marco Tató, Luisa Garofano, Marina Ciomei
  • 4-Demethoxy-4'-deoxydoxorubicin
    Patent number: 4325947
    Abstract: A new anthracycline glycoside, which is 4-demethoxy-4'-deoxydoxorubicin, provided with outstanding antitumoral activity also by oral route, has been prepared by condensation of 4-demethoxydaunomycinone with 2,3,4,6-tetradeoxy-3-trifluoroacetamido-L-threo-hexopyranosyl chloride.By elimination of the protecting group from the so obtained glycoside through a mild alkaline hydrolysis, 4-demethoxy-4'-deoxydaunorubicin was obtained which was successively brominated to give the corresponding 14-bromo derivative. By a subsequent hydrolysis with sodium formate the brominated intermediate was transformed into 4-demethoxy-4'-deoxydoxorubicin eventually isolated as its hydrochloride.
    Type: Grant
    Filed: May 12, 1981
    Date of Patent: April 20, 1982
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Sergio Penco, Giuliano Franchi, Federico Arcamone, Annamaria Casazza
  • Antitumordeoxy-anthracyclines and use thereof
    Patent number: 4218440
    Abstract: Compounds having the formula: ##STR1## wherein R is H or OH, and which are useful in treating certain mammalian tumors, are prepared from 9,10-anhydro-N-trifluoroacetyldaunorubicin, a known compound.
    Type: Grant
    Filed: September 13, 1978
    Date of Patent: August 19, 1980
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Sergio Penco, Giuliano Franchi, Federico Arcamone
  • Disaccharide analogs of antitumor anthracyclines, process for their preparation and use thereof
    Patent number: 4169142
    Abstract: Anthracycline disaccharides having antitumor activity are prepared by condensing N-trifluoroacetyldaunomycin with a 1-halosugar in the presence of a silver salt such as AgSO.sub.3 CF.sub.3 as catalyst to form a protected di-glycoside which upon mild alkaline hydrolysis yields the novel disaccharides.
    Type: Grant
    Filed: November 14, 1977
    Date of Patent: September 25, 1979
    Assignee: Societa' Farmaceutici Italia S.p.A.
    Inventors: Sergio Penco, Giuliano Franchi, Federico Arcamone