Patents by Inventor Giuliano Frigerio

Giuliano Frigerio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6544965
    Abstract: The present invention relates to the use of a compound having general formula (I) as described hereunder wherein R═H (FPA compound) or R═CH3 (FPB compound) for the preparation of compositions with an antioxidant activity for administering to human beings for therapeutic or nutritional purposes. The invention also relates to a process for the preparation of a compound having general formula (I) as defined above characterized in that a cellular culture is obtained from an Ajuga reptans plant, said culture being subsequently subjected to cultivation under aerobic conditions, in a liquid medium containing assimilable carbon and nitrogen sources, and mineral salts.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: April 8, 2003
    Assignee: Giuliani S.p.A.
    Inventors: Anacleto Minghetti, Nicoletta Crespi Perellino, Aldo Roda, Bruno Danieli, Giuliano Frigerio, Danila Ingrid Marchioretto
  • Patent number: 6368580
    Abstract: The subject of the present invention is a composition suitable as food integrator and for the treatment of intestinal disorders and alterations of the bacterial flora, characterized in that it contains as active principle a combination of Bacillus coagulans and lysine. A further subject of the present invention is a method for the growth and development of cultures of Bacillus coagulans in the presence of lysine, as well as the use of these bacterial cultures thus produced and developed in the preparation of compositions suitable both as food integrators and as pharmaceutical compositions.
    Type: Grant
    Filed: January 3, 2000
    Date of Patent: April 9, 2002
    Assignee: Giuliani S.p.A
    Inventors: Moreno Bondi, Paola Messi, Giuliano Frigerio, Danila Ingrid Marchioretto, Valter Gatti
  • Publication number: 20010024809
    Abstract: The present invention relates to the use of a compound having general formula (I) as described hereunder 1
    Type: Application
    Filed: January 12, 2001
    Publication date: September 27, 2001
    Inventors: Anacleto Minghetti, Nicoletta Crespi Perellino, Aldo Roda, Bruno Danieli, Giuliano Frigerio, Danila Ingrid Marchioretto
  • Patent number: 5449520
    Abstract: The invention provides a pharmaceutical composition for the rectal administration of active principles which exhibit a prevalently topical medication action at the colon level, characterized in that said active principles are formulated in a fluid vehicle able to generate a foam on rectal administration.
    Type: Grant
    Filed: October 1, 1993
    Date of Patent: September 12, 1995
    Assignee: Giuliani S.p.A.
    Inventors: Giuliano Frigerio, Enzo Giorgetti, Emilia Chiodini
  • Patent number: 5321019
    Abstract: Compounds of formula I: ##STR1## in which the various R groups have the meanings defined in the disclosure are useful as medicaments for the treatment of hepatobiliary diseases.
    Type: Grant
    Filed: January 11, 1993
    Date of Patent: June 14, 1994
    Assignee: Giuliani S.p.A.
    Inventors: Giangermano Giuliani, Giuliano Frigerio, Roberto Pellicciari
  • Patent number: 5175320
    Abstract: Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6.alpha.-hydroxy-7-keto-derivatives.
    Type: Grant
    Filed: September 18, 1991
    Date of Patent: December 29, 1992
    Assignee: Giuliani S.p.A.
    Inventors: Roberto Pellicciari, Aldo Roda, Giuliano Frigerio
  • Patent number: 5166374
    Abstract: Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carboanions the corresponding derivatives which have previously been protected, and subsequently deprotecting and decarboxylating them.
    Type: Grant
    Filed: September 18, 1991
    Date of Patent: November 24, 1992
    Assignee: Giuliani S.p.A.
    Inventors: Roberto Pellicciari, Aldo Roda, Giuliano Frigerio
  • Patent number: 5124144
    Abstract: The invention provides an orally administered pharmaceutical composition for use in gastrointestinal washes, particularly for diagnostic use, or as a cathartic laxative, of the type containing polyethyleneglycol, anhydrous sodium sulphate, sodium bicarbonate, sodium chloride and potassium chloride, characterized by also containing the following components: saccharin, acesulfame-K and a flavoring chosen from the following: mandarin, fresh fruit flavoring.
    Type: Grant
    Filed: April 11, 1990
    Date of Patent: June 23, 1992
    Assignee: Giuliani S.p.A.
    Inventors: Enzo Giorgetti, Virginio Castagnola, deceased, Giuliano Frigerio
  • Patent number: 5061701
    Abstract: A compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by fluorination of the suitably protected 6-hydroxy-7-keto-derivatives.
    Type: Grant
    Filed: April 9, 1990
    Date of Patent: October 29, 1991
    Assignee: Giuliani S.p.A.
    Inventors: Roberto Pellicciari, Aldo Roda, Giuliano Frigerio
  • Patent number: 5057509
    Abstract: Compounds of general formula I ##STR1## wherein R.sub.1 is hydrogen or hydroxy, and the hydroxy group at the 7-position can be either in .alpha. or .beta. configuration, are valuable in human therapy. Compounds I can be prepared by reacting with succinic acid carbonanions the corresponding derivatives which have previously been protected, and subsequently deprotecting and decarboxylating them.
    Type: Grant
    Filed: April 9, 1990
    Date of Patent: October 15, 1991
    Assignee: Giuliani S.p.A.
    Inventors: Roberto Pellicciari, Aldo Roda, Giuliano Frigerio
  • Patent number: 4981983
    Abstract: New derivatives of chenodeoxycholic, ursodeoxy cholic, cholic and ursocholic acids, bearing a methyl group in the side chain in an alfa position to the carboxylic group, the corresponding nor- and di-nor- derivatives, and the corresponding conjugates with taurine and glycine, are described.The compounds of the invention are prepared by methylation of the esters with methyl iodide in the presence of lithium-dialkylamides.
    Type: Grant
    Filed: October 2, 1989
    Date of Patent: January 1, 1991
    Assignee: Gipharmex S.p.A.
    Inventors: Virginio Castagnola, E. Giuliano Frigerio, Roberto Pellicciari, Aldo Roda
  • Patent number: 4931038
    Abstract: The present invention relates to a complex of products useful for the not-invasive and rapid treatment of the biliary calculosis of cholesterolic nature. It is based upon the coupling of a special apparatus generating medium-energy or medium-low-energy ultrasounds with pharmaceutical compositions based on biliary acids, capable of de-saturating bile super-saturated with cholesterol.
    Type: Grant
    Filed: December 2, 1987
    Date of Patent: June 5, 1990
    Assignee: Gipharmex S.p.A.
    Inventors: Giuliano Frigerio, Aldo Roda, Enrico Roda
  • Patent number: 4921848
    Abstract: Compounds of formula I ##STR1## wherein: R.sub.1 is hydrogen or hydroxy, and the methyl and hydroxy groups at 6- and 7-positions respectively can be either in .alpha. or .beta. configuration, are useful in human therapy. Compounds I are prepared by methylation of the corresponding appropriately protected 7-keto-derivatives.
    Type: Grant
    Filed: October 19, 1988
    Date of Patent: May 1, 1990
    Assignee: Gipharmex S.P.A.
    Inventors: Giuliano Frigerio, Roberto Pellicciari, Aldo Roda
  • Patent number: 4892868
    Abstract: New derivatives of chenodeoxycholic, ursodeoxycholic, cholic and ursocholic acids, bearing a methyl group in the side chain, in an alfa position to the carboxylic group, the corresponding nor- and di-nor- derivatives, and the corresponding conjugates with taurine and glycine, are described.The compounds of the invention are prepared by methylation of the esters with methyl iodide in the presence of lithium-dialkylamides.
    Type: Grant
    Filed: July 10, 1986
    Date of Patent: January 9, 1990
    Assignee: Gipharmex, S.p.A.
    Inventors: Virginio Castagnola, E. Giuliano Frigerio, Roberto Pellicciari, Aldo Roda
  • Patent number: 4565810
    Abstract: New derivatives of chenodeoxycholic, ursodeoxycholic, cholic and ursocholic bile acids having in the side chain in the 19 position a cyclopropane ring are described together with taurine and glycine conjugated derivatives thereof.The compounds of the invention, prepared from suitable olephinic intermediates by reaction with alkyl diazoacetates or by Simmons-Smith reaction and optional conjugation with taurine or glycine, are endowed with interesting therapeutic properties.
    Type: Grant
    Filed: April 24, 1984
    Date of Patent: January 21, 1986
    Assignee: Lehner A.G.
    Inventors: Virginio Castagnola, E. Giuliano Frigerio, Roberto Pellicciari