Patents by Inventor Giulio Fiorentini

Giulio Fiorentini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-alkylamides of d(+)-carnitine having antibacterial activity, process for their preparation and pharmaceutical and cosmetic compositions containing same
    Patent number: 5258552
    Abstract: N-alkylamide or D(+)-carnitrine having general formula ##STR1## wherein X.sup.- is OH.sup.- or the anion of a pharmacologically acceptable acid (preferably Cl.sup.-), andR is a straight C.sub.10 -C.sub.16 alkyl radical are prepared via transamination by reacting (D(+)-carnitinamide halogenide with an amine or formula NH.sub.2 R wherein R has the above-identified meaning in an acid environment (e.g. H.sub.3 PO.sub.4) in the presence of a high-boiling solvent (e.g. ethylene glycol).N-alkylamides (I) are endowed with potent anti-bacterial activity and are suitable for preparing pharmaceutical and cosmetic compositions.
    Type: Grant
    Filed: September 19, 1989
    Date of Patent: November 2, 1993
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Paolo Cavazza, Giulio Fiorentini
  • N-alkylamides of D,L and L(-)-carnitine having antibacterial activity, process for their preparation and pharmaceutical and cosmetic compositions containing same
    Patent number: 5045306
    Abstract: N-alkylamide of DL and L(-)-carnitine having general formula (I) ##STR1## wherein: x.sup.- is OH.sup.- or the anion of a pharmacologically acceptable acid (preferably Cl.sup.-`), andR is a straight C.sub.10 -C.sub.16 alkyl radicalare prepared via transamination by reacting DL or L(-)-carnitinamide halogenide with an amine of formula NH.sub.2 R wherein R has the above-identified meaning in an acid environment (e.g. H.sub.3 PO.sub.4) in the presence of a high-boiling solvent (e.g. ethylene glycol).N-alkylamides (I) are endowed with potent antibacterial activity and are suitable for preparing pharmaceutical and cosmetic compositions.
    Type: Grant
    Filed: November 4, 1988
    Date of Patent: September 3, 1991
    Assignee: Avantgarde S.p.A.
    Inventors: Paolo Cavazza, Giulio Fiorentini
  • N-alkylamides of D(+)-carnitine having antibacterial activity, process for their preparation and pharmaceutical and cosmetic compositions containing same
    Patent number: 4871773
    Abstract: N-alkylamide of D(+)-carnitine having general formula (I) ##STR1## wherein: X.sup.- is OH.sup.- or the anion of a pharmacologically acceptable acid (preferably Cl.sup.-), andR is a straight C.sub.10 -C.sub.16 alkyl radicalare prepared via transamination by reacting D(+)-carnitinamide halogenide with an amine of formula NH.sub.2 R wherein R has the above-identified meaning in an acid environment (e.g. H.sub.3 PO.sub.4) in the presence of a high-boiling solvent (e.g. ethylene glycol).N-alkylamides (I) are endowed with potent antibacterial activity and are suitable for preparing pharmaceutical and cosmetic compositions.
    Type: Grant
    Filed: January 11, 1989
    Date of Patent: October 3, 1989
    Assignee: Avantgarde S.p.A.
    Inventors: Paolo Cavazza, Giulio Fiorentini