Abstract: The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivolex vivo applications, such as blood and blood derivatives sterilization.

Abstract: A composition comprising a photoactivatable larvicide and a suitable vector, the latter allowing the larvicide to be ingested by the larvae and a method for controlling mosquito larvae by using said photoactivatable larvicide are disclosed.

Abstract: The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.

Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.

Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization.

Abstract: Cationic phthalocyanine and/or porphyins salts are used as photosterilising agents for microbiologically contaminated waters, particularly for inactivating Gram-positive and Gram-negative bacteria, yeasts, micoplasmas and parasites. Synergistic action for water photosterilisation by the simultaneous use of the cationic phthalocyanine salt and a porphyrin molecule, which performs its photosterilising action by a mechanism identical with that typical of phthalocyanines, and whose visible light absorption spectrum efficiently complements the absorption of phthalocyanines. The photosterilising salts can be added to the water as a solution, or as a powder or tablet.

Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.

Abstract: The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.

Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization.

Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization

Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.

Abstract: The present invention relates to pharmaceutical compositions comprising metal phthalocyanine analogues of formula (I) and metal chelating compounds having a good bioavailability and enhanced photoinactivation properties against Gram negative bacteria; and to their use for in vivolex vivo applications, such as blood and blood derivatives sterilization.

Abstract: Cationic phthalocyanine and/or porphyins salts are used as photosterilising agents for microbiologically contaminated waters, particularly for inactivating Gram-positive and Gram-negative bacteria, yeasts, micoplasmas and parasites. Synergistic action for water photosterilisation by the simultaneous use of the cationic phthalocyanine salt and a porphyrin molecule, which performs its photosterilising action by a mechanism identical with that typical of phthalocyanines, and whose visible light absorption spectrum efficiently complements the absorption of phthalocyanines. The photosterilising salts can be added to the water as a solution, or as a powder or tablet.

Abstract: The invention relates to the utilization of photosensitizers for controlling algae and bacteria in aquaria, whereby compounds of the tetrapyrrol and tetraazopyrrol families having at least one positive charge are used as sensitizers.

Abstract: The present invention is directed tometal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization.

Abstract: The invention relates to compounds of the formula: 1 (I) 1 R1 = R2 = R3 = R4 = —CH3 T4MPyP —CH3 —CH2(CH2)4CH3 mono-C6 —CH2(CH2)8CH3 mono-C10 —CH2(CH2)12CH3 mono-C14 —CH2(CH2)16CH3 mono-C18 —CH2(CH2)20CH3 mono-C22 2 mono-benzyl R1 = R2 = R3 = R4 = tetra-CS —CH2(CH2)4CH3

Abstract: A series of novel positively-charged porphyrins is disclosed which exhibit a markedly increased efficiency in photosensitizing both Gram-positive and Gram-negative bacteria to the action of visible light, causing death to such bacteria when present at much lower concentrations and much shorter irradiation times than those porphyrins taught in the prior art. These porphyrins are characterized by the presence of up to four positive charges in the peripheral substituents and at least one hydrophobic tail comprising between 6 and 22 carbons inclusive, originating at one or more of the charged sites.

Abstract: A series of novel positively-charged porphyrins is disclosed which exhibit a markedly increased efficiency in photosensitizing both Gram-positive and Gram-negative bacteria to the action of visible light, causing death to such bacteria when present at much lower concentrations and much shorter irradiation times than those porphyrins taught in the prior art. These porphyrins are characterized by the presence of up to four positive charges in the peripheral substituents and at least one hydrophobic tail comprising between 6 and 22 carbons inclusive, originating at one or more of the charged sites.

Abstract: The invention relates to the utilization of photosensitizers for controlling algae and bacteria in aquaria, whereby compounds of the tetrapyrrol and tetraazopyrrol families having at least one positive charge are used as sensitizers.

Abstract: The present invention relates to a new pesticide which is based on a photosensitizer or combination of photosensitizers of the tetrapyrrole and/or tetraazapyrrole series which may comprise a biological and/or chemical attractant for pests and to a method of controlling pests using the new pesticide.