Patents by Inventor Giuseppe ALONCI

Giuseppe ALONCI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11707473
    Abstract: The invention relates to a method for the stabilization of a polysaccharide (hyaluronic acid) with a biomolecule—amino acid—through crosslinking, to generate a bionic hydrogel based on physiological building blocks for applications in regenerative medicine. The designed biosimilar hydrogel is intended to be used in regenerative medicine for the purpose of regenerate, rejuvenate and/or restore the structure or function of impaired or damaged tissues, and to promote healing. The manufacture method is composed of a single step that includes mixing L-lysine and hyaluronic acid sodium salt in an aqueous saline solution with either EDC/NHS as coupling agent.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: July 25, 2023
    Assignee: Qventis GmbH
    Inventors: Lidia de Oliveira Barbosa Nachbaur, Giuseppe Alonci
  • Publication number: 20200277449
    Abstract: The invention relates to a hybrid hydrogel, in particular degradable or non-degradable, comprising a first hydrogel polymer of formula (I) in association with an alginate hydrogel polymer, and optionally organosilica particles in particular degradable or non-degradable nanoparticles, or porous silicon particles; pharmaceutical, veterinary and/or cosmetic compositions thereof; and uses thereof as a medicament. The invention notably relates to the use of such hybrid hydrogel in the treatment of fistulas and physiological leaks/leakages, notably in the gastrointestinal tract. The present invention finds applications in the therapeutic and diagnostic medical technical fields and also in cosmetic and veterinary technical fields.
    Type: Application
    Filed: September 17, 2018
    Publication date: September 3, 2020
    Inventors: Luisa DE COLA, Silvana PERRETTA, Giuseppe ALONCI, Pietro RIVA, Etienne PIANTANIDA, Ludovica GUERRIERO
  • Publication number: 20200179419
    Abstract: The invention relates to a method for the stabilization of a polysaccharide (hyaluronic acid) with a biomolecule—amino acid—through crosslinking, to generate a bionic hydrogel based on physiological building blocks for applications in regenerative medicine. The designed biosimilar hydrogel is intended to be used in regenerative medicine for the purpose of regenerate, rejuvenate and/or restore the structure or function of impaired or damaged tissues, and to promote healing. The manufacture method is composed of a single step that includes mixing L-lysine and hyaluronic acid sodium salt in an aqueous saline solution with either EDC/NHS as coupling agent.
    Type: Application
    Filed: December 11, 2019
    Publication date: June 11, 2020
    Inventors: Lidia de Oliveira Barbosa Nachbaur, Giuseppe Alonci
  • Publication number: 20200138711
    Abstract: The invention relates to a hydrogel, in particular degradable or non degradable, comprising monomers of formula (I) and organosilica particles or porous silicon particles covalently bound thereto, optionally with non covalently bound organosilica and/or silicon particles mixed therewith, in particular degradable organosilica nanoparticles or core-shell nanocapsules; pharmaceutical, veterinary or cosmetic compositions thereof; and uses thereof as a medicament. The present invention finds applications in the therapeutic and diagnostic medical technical fields and also in cosmetic and veterinary technical fields.
    Type: Application
    Filed: January 17, 2018
    Publication date: May 7, 2020
    Inventors: Luisa DE COLA, Giuseppe ALONCI, Silvana PERRETTA, Pietro RIVA, Federica FIORINI