Patents by Inventor Giuseppe Alvaro

Giuseppe Alvaro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HYDANTOIN MODULATORS OF KV3 CHANNELS
    Publication number: 20200039970
    Abstract: The invention provides the compound of formula (I): Said compound bein-ganinhibitor of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
    Type: Application
    Filed: December 15, 2017
    Publication date: February 6, 2020
    Inventors: Giuseppe ALVARO, Agostino MARASCO
  • HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS
    Publication number: 20190192516
    Abstract: The disclosure provides compounds of formula (I): said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
    Type: Application
    Filed: February 26, 2019
    Publication date: June 27, 2019
    Inventors: Giuseppe ALVARO, Paolo DAMBRUOSO, Simona TOMMASI, Anne DECOR, Charles LARGE, Agostino MARASCO
  • NOVEL COMPOUNDS
    Publication number: 20190161479
    Abstract: The present invention provides compounds of the formula (I) and their use as Kv3 modulators.
    Type: Application
    Filed: July 28, 2017
    Publication date: May 30, 2019
    Inventors: Giuseppe ALVARO, Agostino MARASCO, Guido MARCONI
  • Hydantoin derivatives useful as Kv3 inhibitors
    Patent number: 10265316
    Abstract: The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: April 23, 2019
    Assignee: AUTIFONY THERAPEUCTICS LIMITED
    Inventors: Giuseppe Alvaro, Paolo Dambruoso, Simona Tommasi, Anne Decor, Charles Large, Agostino Marasco
  • TRIAZOLES AS KV3 INHIBITORS
    Publication number: 20190071405
    Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
    Type: Application
    Filed: November 6, 2018
    Publication date: March 7, 2019
    Inventors: Agostino Marasco, Giuseppe Alvaro, Anne Dècor, Dieter Hamprecht, Paolo Dambruoso, Simona Tommasi
  • NOVEL COMPOUNDS
    Publication number: 20190000849
    Abstract: The invention provides compounds of formula (I): Said compounds being modulators of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
    Type: Application
    Filed: September 7, 2018
    Publication date: January 3, 2019
    Inventors: Giuseppe ALVARO, Agostino MARASCO
  • MODULATORS OF KV3 CHANNELS TO TREAT PAIN
    Publication number: 20190000848
    Abstract: The present invention provides a modulator of Kv3.1 and/or Kv3.2 and/or Kv3.3 channels for use in the prophylaxis or treatment of pain. Modulators for use in the prophylaxis or treatment of pain include compounds of formula (I) or a pharmaceutically acceptable salt and/or solvate thereof and/or derivative thereof: (I).
    Type: Application
    Filed: December 9, 2016
    Publication date: January 3, 2019
    Inventors: Charles LARGE, Giuseppe ALVARO
  • Triazoles as KV3 inhibitors
    Patent number: 10160730
    Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
    Type: Grant
    Filed: July 12, 2016
    Date of Patent: December 25, 2018
    Assignee: Autifony Therapeutics Limited
    Inventors: Agostino Marasco, Giuseppe Alvaro, Anne Dècor, Dieter Hamprecht, Paolo Dambruoso, Simona Tommasi
  • IMIDAZOLIDINEDIONE DERIVATIVES
    Publication number: 20180338974
    Abstract: The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.
    Type: Application
    Filed: July 30, 2018
    Publication date: November 29, 2018
    Inventors: Giuseppe ALVARO, Anne Decor, Stefano fontana, Dieter Hamprecht, Charles Large, Agostino Marasco
  • Compounds
    Patent number: 10098881
    Abstract: Methods for the treatment of Fragile X that includes administering to a subject in need thereof a compound of formula (I): are described herein.
    Type: Grant
    Filed: October 11, 2017
    Date of Patent: October 16, 2018
    Assignee: Autifony Therapeutics Limited
    Inventors: Giuseppe Alvaro, Agostino Marasco
  • Imidazolidinedione derivatives
    Patent number: 10058551
    Abstract: The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: August 28, 2018
    Assignee: Autifony Therapeutics Limited
    Inventors: Giuseppe Alvaro, Anne Decor, Stefano Fontana, Dieter Hamprecht, Charles Large, Agostino Marasco
  • NOVEL COMPOUNDS
    Publication number: 20180036308
    Abstract: Methods for the treatment of Fragile X that includes administering to a subject in need thereof a compound of formula (I): are described herein.
    Type: Application
    Filed: October 11, 2017
    Publication date: February 8, 2018
    Inventors: Giuseppe ALVARO, Agostino MARASCO
  • IMIDAZOLIDINEDIONE DERIVATIVES
    Publication number: 20180021336
    Abstract: The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.
    Type: Application
    Filed: October 2, 2017
    Publication date: January 25, 2018
    Inventors: Giuseppe ALVARO, Anne DECOR, Stefano FONTANA, Dieter HAMPRECHT, Charles LARGE, Agostino MARASCO
  • Imidazolidinedione derivatives
    Patent number: 9849131
    Abstract: The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: December 26, 2017
    Assignee: AUTIFONY THERAPEUTICS LIMITED
    Inventors: Giuseppe Alvaro, Anne Decor, Stefano Fontana, Dieter Hamprecht, Charles Large, Agostino Marasco
  • Compounds
    Patent number: 9833452
    Abstract: Compounds of formula (I): are described herein. Compounds of the disclosure are modulators of Kv3 channels and may be used in the prophylaxis or treatment of related disorders.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: December 5, 2017
    Assignee: AUTIFONY THERAPEUTICS LIMITED
    Inventors: Giuseppe Alvaro, Agostino Marasco
  • HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS
    Publication number: 20170273981
    Abstract: The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
    Type: Application
    Filed: June 13, 2017
    Publication date: September 28, 2017
    Inventors: Giuseppe ALVARO, Paolo DAMBRUOSO, Simona TOMMASI, Anne DECOR, Charles LARGE, Agostino MARASCO
  • IMIDAZOLIDINEDIONE DERIVATIVES
    Publication number: 20170065585
    Abstract: The invention provides a compound of formula (Ia), and pharmaceutically acceptable salts thereof. The invention also provides use of the compounds or salts as modulators of Kv3.1 and/or Kv3.2, and in the treatment of diseases or disorders where a modulator of Kv3.1 and/or Kv3.2 is required, such as depression and mood disorders, hearing disorders, schizopherenea, substance abuse disorders, sleep disorders or epilepsy.
    Type: Application
    Filed: November 10, 2016
    Publication date: March 9, 2017
    Inventors: Giuseppe ALVARO, Anne DECOR, Stefano FONTANA, Dieter HAMPRECHT, Charles LARGE, Agostino MARASCO
  • TRIAZOLES AS KV3 INHIBITORS
    Publication number: 20160318882
    Abstract: Compounds of formula (I) are of use in the modulation of Kv3.1, Kv.3.2 and Kv3.3 channels and have utility in the treatment or prevention of related disorders.
    Type: Application
    Filed: July 12, 2016
    Publication date: November 3, 2016
    Inventors: Agostino MARASCO, Giuseppe ALVARO, Anne DÈCOR, Dieter HAMPRECHT, Paolo DAMBRUOSO, Simona TOMMASI
  • NOVEL COMPOUNDS
    Publication number: 20160317537
    Abstract: Compounds of formula (I): are described herein. Compounds of the disclosure are modulators of Kv3 channels and may be used in the prophylaxis or treatment of related disorders.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 3, 2016
    Inventors: Giuseppe ALVARO, Agostino MARASCO
  • HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS
    Publication number: 20160251340
    Abstract: The invention provides compounds of formula (I): Said compounds being inhibitors of Kv3 channels and of use in the prophylaxis or treatment of related disorders.
    Type: Application
    Filed: April 7, 2016
    Publication date: September 1, 2016
    Inventors: Giuseppe ALVARO, Paolo DAMBRUOSO, Simona TOMMASI, Anne DECOR, Charles LARGE, Agostino MARASCO