Abstract: A system and method for facilitating an instant lottery game with both physical and virtual instant lottery tickets, and more particularly to a system and method for facilitating virtual instant lottery ticket creation, virtual instant lottery ticket selling, virtual instant lottery ticket transferring, virtual instant lottery ticket scratching, and virtual instant lottery ticket redemption. The instant lottery ticket system and method of various embodiments provides the seamless integration with existing physical instant lottery game and ticket systems (and processes thereof), substantially the same overall player experience as provided with physical instant lottery tickets.

Abstract: A system and method for facilitating an instant lottery game with both physical and virtual instant lottery tickets, and more particularly to a system and method for facilitating virtual instant lottery ticket creation, virtual instant lottery ticket selling, virtual instant lottery ticket transferring, virtual instant lottery ticket scratching, and virtual instant lottery ticket redemption. The instant lottery ticket system and method of various embodiments provides the seamless integration with existing physical instant lottery game and ticket systems (and processes thereof), substantially the same overall player experience as provided with physical instant lottery tickets.

Abstract: Compositions for intravenous infusion of istaroxime, or a metabolite of istaroxime, in human patients suffering from heart failure are disclosed. Likewise, methods for extended infusion of istaroxime or its metabolites in individuals with heart failure are disclosed. In particular, some methods disclosed herein include the infusion of istaroxime, or a metabolite thereof, for a period of time that is greater than six hours in order to improve cardiac relaxation without triggering arrhythmogenic events in an individual suffering from heart failure. Other methods include administration of istaroxime until certain plasma concentration thresholds of istaroxime metabolites are achieved. Also disclosed are istaroxime metabolites with selective SERCA2a activation.

Abstract: Disclosed are compounds of formula (I), wherein X, Y, Z are annular atoms comprised in a five-membered carbocyclic or heterocyclic ring, selected from the group consisting of CH, NH, N, O, S; said carbocyclic or heterocyclic ring being optionally substituted with amino (C1-C4) linear or branched alkyl or guanidine or guanidino (C1-C4) linear or branched alkyl; with the proviso that the heterocycle ring is not furyl; n is 0 or 1; R is H or OH; the dotted line represents an optional double bond C?C; the thick line represents a bond in the ? configuration; the wavy line represents a bond both in the ? and ? configuration; their enantiomeric and/or diastereomeric mixtures, their pharmaceutically acceptable salts, their solvates, hydrates; their metabolite and metabolic precursors. The compounds of formula (I) are for use as medicaments, in particular for the treatment of acute or chronic heart failure. Oral administration is also possible.

Abstract: Compositions for intravenous infusion of istaroxime, or a metabolite of istaroxime, in human patients suffering from heart failure are disclosed. Likewise, methods for extended infusion of istaroxime or its metabolites in individuals with heart failure are disclosed. In particular, some methods disclosed herein include the infusion of istaroxime, or a metabolite thereof, for a period of time that is greater than six hours in order to improve cardiac relaxation without triggering arrhythmogenic events in an individual suffering from heart failure. Other methods include administration of istaroxime until certain plasma concentration thresholds of istaroxime metabolites are achieved. Also disclosed are istaroxime metabolites with selective SERCA2a activation.

Abstract: Compositions for intravenous infusion of istaroxime, or a metabolite of istaroxime, in human patients suffering from heart failure are disclosed. Likewise, methods for extended infusion of istaroxime or its metabolites in individuals with heart failure are disclosed. In particular, some methods disclosed herein include the infusion of istaroxime, or a metabolite thereof, for a period of time that is greater than six hours in order to improve cardiac relaxation without triggering arrhythmogenic events in an individual suffering from heart failure. Other methods include administration of istaroxime until certain plasma concentration thresholds of istaroxime metabolites are achieved. Also disclosed are istaroxime metabolites with selective SERCA2a activation.

Abstract: A system and method for facilitating an instant lottery game with both physical and virtual instant lottery tickets, and more particularly to a system and method for facilitating virtual instant lottery ticket creation, virtual instant lottery ticket selling, virtual instant lottery ticket transferring, virtual instant lottery ticket scratching, and virtual instant lottery ticket redemption.

Abstract: Compositions for intravenous infusion of istaroxime, or a metabolite of istaroxime, in human patients suffering from heart failure are disclosed. Likewise, methods for extended infusion of istaroxime or its metabolites in individuals with heart failure are disclosed. In particular, some methods disclosed herein include the infusion of istaroxime, or a metabolite thereof, for a period of time that is greater than six hours in order to improve cardiac relaxation without triggering arrhythmogenic events in an individual suffering from heart failure. Other methods include administration of istaroxime until certain plasma concentration thresholds of istaroxime metabolites are achieved. Also disclosed are istaroxime metabolites with selective SERCA2a activation.

Abstract: Disclosed are compounds of formula (I), wherein X, Y, Z are annular atoms comprised in a five-membered carbocyclic or heterocyclic ring, selected from the group consisting of CH, NH, N, O, S; said carbocyclic or heterocyclic ring being optionally substituted with amino (C1-C4) linear or branched alkyl or guanidine or guanidino (C1-C4) linear or branched alkyl; with the proviso that the heterocycle ring is not furyl; n is 0 or 1; R is H or OH; the dotted line represents an optional double bond C?C; the thick line represents a bond in the ? configuration; the wavy line represents a bond both in the ? and ? configuration; their enantiomeric and/or diastereomeric mixtures, their pharmaceutically acceptable salts, their solvates, hydrates; their metabolite and metabolic precursors. The compounds of formula (I) are for use as medicaments, in particular for the treatment of acute or chronic heart failure. Oral administration is also possible.

Abstract: Compositions for intravenous infusion of istaroxime, or a metabolite of istaroxime, in human patients suffering from heart failure are disclosed. Likewise, methods for extended infusion of istaroxime or its metabolites in individuals with heart failure are disclosed. In particular, some methods disclosed herein include the infusion of istaroxime, or a metabolite thereof, for a period of time that is greater than six hours in order to improve cardiac relaxation without triggering arrhythmogenic events in an individual suffering from heart failure. Other methods include administration of istaroxime until certain plasma concentration thresholds of istaroxime metabolites are achieved. Also disclosed are istaroxime metabolites with selective SERCA2a activation.

Abstract: The apparatus (SW) has a plurality of input/output ports (P1, P2, P3, P4, P5) for receiving and transmitting data packets, and comprises a data packets handling circuitry (DPL) arranged to forward data packets between the input/output ports (P1, P2, P3, P4, P5) and an internal apparatus controller (CPL) arranged to control the data packet handling circuitry (DPL); the apparatus controller (CPL) is arranged to store (MEM) at least one state transition table (TT) to be used for controlling the forwarding of data packets by the data packets handling circuitry (DPL); the apparatus controller (CPL) is arranged to use the state transition table (TT) for implementing at least one finite state machine (FSM); the apparatus controller (CPL) is arranged to use the state transition table (TT) for handling separately distinct incoming data packets flows through corresponding distinct instances of finite state machine; the state transition table (TT) corresponds to the combination of a state table (ST), a condition table (

Abstract: A method for data inspection includes upon receiving an out-of-order part of a sequence of parts, checking the out-of-order part for matching in forward and backward direction of the sequence; temporarily saving a forward state and a backward state of said both checkings; and upon receiving an in-order part of the sequence, checking the in-order part for matching in the forward direction of the sequence and if the in-order packet is within a gap between the first part and the last part of the sequence the in-order part is also checked for matching in backward direction of the sequence. The backward state or the forward and backward state are updated or temporarily saved.

Abstract: The apparatus (SW) has a plurality of input/output ports (P1, P2, P3, P4, P5) for receiving and transmitting data packets, and comprises a data packets handling circuitry (DPL) arranged to forward data packets between the input/output ports (P1, P2, P3, P4, P5) and an internal apparatus controller (CPL) arranged to control the data packet handling circuitry (DPL); the apparatus controller (CPL) is arranged to store (MEM) at least one state transition table (TT) to be used for controlling the forwarding of data packets by the data packets handling circuitry (DPL); the apparatus controller (CPL) is arranged to use the state transition table (TT) for implementing at least one finite state machine (FSM); the apparatus controller (CPL) is arranged to use the state transition table (TT) for handling separately distinct incoming data packets flows through corresponding distinct instances of finite state machine; the state transition table (TT) corresponds to the combination of a state table (ST), a condition table (

Abstract: A method for data inspection includes upon receiving an out-of-order part of a sequence of parts, checking the out-of-order part for matching in forward and backward direction of the sequence; temporarily saving a forward state and a backward state of said both checkings; and upon receiving an in-order part of the sequence, checking the in-order part for matching in the forward direction of the sequence and if the in-order packet is within a gap between the first part and the last part of the sequence the in-order part is also checked for matching in backward direction of the sequence. The backward state or the forward and backward state are updated or temporarily saved.

Abstract: The apparatus (SW) has a plurality of input/output ports (P1, P2, P3, P4, P5) for receiving and transmitting data packets, and comprises a data packets handling circuitry (DPL) arranged to forward data packets between the input/output ports (P1, P2, P3, P4, P5) and an internal apparatus controller (CPL) arranged to control the data packet handling circuitry (DPL); the apparatus (SW) has a control port (PC) for communication between the internal apparatus controller (CPL) and an external network controller (NWC); the apparatus controller (CPL) is arranged to store (MEM) at least one state transition table (TT) to be used for controlling the forwarding of data packets by the data packets handling circuitry (DPL); the apparatus controller (DPL) is arranged to use said at least one state transition table (TT) for implementing at least one finite state machine (FSM); the apparatus controller (DPL) is arranged to use said at least one state transition table (TT) for handling separately distinct incoming data packet

Abstract: A method for analyzing a data flow includes: (a) extracting packet information of a packet, (b) determining a status of the packet based on the extracted packet information by applying at least one probabilistic filter to the packet and storing the packet for later inspection based on the status of the packet indicating that the packet is out-of sequence, and (c) inspecting the stored packet based on inspection rules. Upon a partial match of an inspection rule with the extracted packet information, a result of the inspection is temporarily stored. Already stored packets are inspected based on the already stored packets being in-order with already inspected packets. Upon a total match of at least one of the inspection rules, a predetermined action is performed and the stored result is deleted. The at least one probabilistic filter includes a connection Bloom filter and a sequence Bloom filter.

Abstract: A method for analyzing a data flow includes: (a) extracting packet information of a packet, (b) determining a status of the packet based on the extracted packet information by applying at least one probabilistic filter to the packet and storing the packet for later inspection based on the status of the packet indicating that the packet is out-of sequence, and (c) inspecting the stored packet based on inspection rules. Upon a partial match of an inspection rule with the extracted packet information, a result of the inspection is temporarily stored. Already stored packets are inspected based on the already stored packets being in-order with already inspected packets. Upon a total match of at least one of the inspection rules, a predetermined action is performed and the stored result is deleted. The at least one probabilistic filter includes a connection Bloom filter and a sequence Bloom filter.

Abstract: A method for analyzing a data flow includes extracting packet information of a packet of the data flow, determining the status of the packet and the status of the data flow based on the extracted packet information and storing the packet for later inspection when the status of the packet and/or the status of the data flow indicate that the packet is out-of sequence, and inspecting the packet and/or the stored packet based on inspection rules. Upon a partial match of at least one of the inspection rules with the extracted packet information, a result of the inspection of the packet is temporarily stored. Already stored packets are inspected when they are in-order with already inspected packets. Upon a total match of at least one of the inspection rules, a predetermined action is performed and the stored result is deleted.

Abstract: Compound of formula (I), wherein the symbol have the meaning reported in the text; for preparing a medicament for the prevention and/or treatment of proteinuria, glomerulosclerosis or renal failure.

Abstract: The apparatus (SW) has a plurality of input/output ports (P1, P2, P3, P4, P5) for receiving and transmitting data packets, and comprises a data packets handling circuitry (DPL) arranged to forward data packets between the input/output ports (P1, P2, P3, P4, P5) and an internal apparatus controller (CPL) arranged to control the data packet handling circuitry (DPL); the apparatus (SW) has a control port (PC) for communication between the internal apparatus controller (CPL) and an external network controller (NWC); the apparatus controller (CPL) is arranged to store (MEM) at least one state transition table (TT) to be used for controlling the forwarding of data packets by the data packets handling circuitry (DPL); the apparatus controller (DPL) is arranged to use said at least one state transition table (TT) for implementing at least one finite state machine (FSM); the apparatus controller (DPL) is arranged to use said at least one state transition table (TT) for handling separately distinct incoming data packet