Patents by Inventor Giuseppe Caputo
Giuseppe Caputo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11266962Abstract: Described herein is a reactor (1) includes: a first reaction volume (V1), a second reaction volume (V2), wherein: the first reaction volume (V1) is in fluid communication with an inlet port for an oxidizer agent (OX_IN), an inlet port for at least one first reactant (R1_IN) and an outlet port for at least one reaction product (P1_OUT), said second reaction volume (V2) is in fluid communication with an inlet port for at least one second reactant (R2_IN), an outlet port for at least one second reaction product (P2_OUT) and is furthermore in thermal exchange relationship with said first reaction volume (V1), wherein, during operation, in said first reaction volume (V1) an oxidation reaction occurs between said at least one first reactant and said oxidizer agent with the formation of said at least one first reaction product, and in said second reaction volume (V2) a gasification reaction occurs of said second reactant with the contribution of a thermal energy flow exchanged between the first and the second reaType: GrantFiled: January 27, 2017Date of Patent: March 8, 2022Assignee: Archimede S.R.L.Inventors: Alberto Brucato, Giuseppe Caputo, Franco Grisafi, Francesca Scargiali, Gianluca Minelli, Gaetano Tuzzolino, Calogero Gattuso, Roberto Rizzo, Marialaura Alessi, Fabio Santoro
-
Patent number: 11187465Abstract: A heat exchanger (1; 1*; 100) includes a bundle of tubes (8), each extending in a respective elongation direction (X1) and defining a flow path for a working fluid that extends in the elongation direction, wherein each tube (8) of the bundle of tubes can be supplied with a working fluid; a matrix (6) of thermally conductive material that houses the tubes (8) of the bundle and that is configured, in use, for promoting heat exchange between working fluids that run through corresponding tubes (8) of the bundle; and a shell (4) made of thermally insulating material arranged around the matrix (6), wherein: the matrix (6) is made up of a plurality of sections (10; 10*) arranged aligned in the elongation direction (X1) and alternated by thermal interruptions (12) that extending transversely to the elongation direction (X1).Type: GrantFiled: January 27, 2017Date of Patent: November 30, 2021Assignee: Archimede S.R.L.Inventors: Alberto Brucato, Giuseppe Caputo, Gianluca Tumminelli, Gaetano Tuzzolino, Calogero Gattuso, Roberto Rizzo
-
Publication number: 20190039036Abstract: Described herein is a reactor (1) includes: a first reaction volume (V1), a second reaction volume (V2), wherein: the first reaction volume (V1) is in fluid communication with an inlet port for an oxidizer agent (OX_IN), an inlet port for at least one first reactant (R1_IN) and an outlet port for at least one reaction product (P1_OUT), said second reaction volume (V2) is in fluid communication with an inlet port for at least one second reactant (R2_IN), an outlet port for at least one second reaction product (P2_OUT) and is furthermore in thermal exchange relationship with said first reaction volume (V1), wherein, during operation, in said first reaction volume (V1) an oxidation reaction occurs between said at least one first reactant and said oxidizer agent with the formation of said at least one first reaction product, and in said second reaction volume (V2) a gasification reaction occurs of said second reactant with the contribution of a thermal energy flow exchanged between the first and the second reaType: ApplicationFiled: January 27, 2017Publication date: February 7, 2019Inventors: ALBERTO BRUCATO, GIUSEPPE CAPUTO, FRANCO GRISAFI, FRANCESCA SCARGIALI, GIANLUCA MINELLI, GAETANO TUZZOLINO, CALOGERO GATTUSO, ROBERTO RIZZO, MARIALAURA ALESSI, FABIO SANTORO
-
Publication number: 20190041136Abstract: A heat exchanger (1; 1*; 100) includes a bundle of tubes (8), each extending in a respective elongation direction (X1) and defining a flow path for a working fluid that extends in the elongation direction, wherein each tube (8) of the bundle of tubes can be supplied with a working fluid; a matrix (6) of thermally conductive material that houses the tubes (8) of the bundle and that is configured, in use, for promoting heat exchange between working fluids that run through corresponding tubes (8) of the bundle; and a shell (4) made of thermally insulating material arranged around the matrix (6), wherein: the matrix (6) is made up of a plurality of sections (10; 10*) arranged aligned in the elongation direction (X1) and alternated by thermal interruptions (12) that extending transversely to the elongation direction (X1).Type: ApplicationFiled: January 27, 2017Publication date: February 7, 2019Inventors: ALBERTO BRUCATO, GIUSEPPE CAPUTO, GIANLUCA TUMMINELLI, GAETANO TUZZOLINO, CALOGERO GATTUSO, ROBERTO RIZZO
-
Patent number: 10086346Abstract: A plant for the disposal of wastes includes a supercritical water oxidation reactor, a supercritical water gasification reactor, and a feeding system configured for feeding at least two organic currents of wastes to the supercritical water oxidation reactor and supercritical water gasification reactor and configured for feeding at least one aqueous flow within said plant. The feeding system is configured for feeding the at least one aqueous current with a series flow through the supercritical water oxidation reactor and supercritical water gasification reactor. The feeding system is configured for feeding the at least two organic currents of wastes with a parallel flow through the supercritical water oxidation reactor and supercritical water gasification reactor and so as to selectively feed each of the organic currents of wastes to the supercritical water oxidation reactor or to the supercritical water gasification reactor.Type: GrantFiled: April 11, 2016Date of Patent: October 2, 2018Assignee: ARCHIMEDE S.R.L.Inventors: Alberto Brucato, Giuseppe Caputo, Franco Grisafi, Francesca Scargiali, Gianluca Tumminelli, Gaetano Tuzzolino, Roberto D'Agostino, Roberto Rizzo
-
Publication number: 20180117561Abstract: A plant for the disposal of wastes includes a supercritical water oxidation reactor, a supercritical water gasification reactor, and a feeding system configured for feeding at least two organic currents of wastes to the supercritical water oxidation reactor and supercritical water gasification reactor and configured for feeding at least one aqueous flow within said plant. The feeding system is configured for feeding the at least one aqueous current with a series flow through the supercritical water oxidation reactor and supercritical water gasification reactor. The feeding system is configured for feeding the at least two organic currents of wastes with a parallel flow through the supercritical water oxidation reactor and supercritical water gasification reactor and so as to selectively feed each of the organic currents of wastes to the supercritical water oxidation reactor or to the supercritical water gasification reactor.Type: ApplicationFiled: April 11, 2016Publication date: May 3, 2018Applicant: Archimede S.r.l.Inventors: Alberto BRUCATO, Giuseppe CAPUTO, Franco GRISAFI, Francesca SCARGIALI, Gianluca TUMMINELLI, Gaetano TUZZOLINO, Roberto D'AGOSTINO, Roberto RIZZO
-
Publication number: 20140246094Abstract: Asymmetric dyes of the D-?-A type have the Formula (1), including the valence tautomers thereof. The dyes of Formula (1) are suitable for use in dye-sensitized solar cells (DSSC), in photoelectrochemical devices or in photonic devices. A solar cell and a device for photoelectric conversion contain an asymmetric dye of Formula (1). The dyes of Formula (1) are also suitable for conjugating with optically active nanoparticles (NP).Type: ApplicationFiled: August 24, 2012Publication date: September 4, 2014Applicant: PIANETA S.R.L.Inventor: Giuseppe Caputo
-
Patent number: 8624035Abstract: A silane-modified cyanine of Formula (I) includes the valence tautomers thereof: wherein R1 is a linear, saturated or unsaturated alkyl chain, having 1 to 30 carbon atoms, wherein one or more carbon atoms are optionally substituted by a 4-, 5- or 6-membered aromatic or non aromatic cyclic grouping of carbon atoms; R8 and R9 are independently selected from the group consisting of —OCH3, —OCH2CH3, —OCH2CH2CH3, —OCH(CH3)2, —OCH2CH2OCH3, —Cl, —Br, —I, Formula (II), Formula (III), —N(CH3)2, Formula (IV), Formula (V), methyl, ethyl, propyl, isopropyl. The synthesis method and the use as a fluorescent marker are for inorganic solid supports, for example silica nanoparticles, and/or for biomolecules such as peptides, antibodies, DNA, RNA, etc.Type: GrantFiled: October 21, 2009Date of Patent: January 7, 2014Assignee: Universita' Degli Studi di TorinoInventors: Giuseppe Caputo, Ivana Miletto, Chiara Alessandra Bertolino, Gianmario Martra, Salvatore Coluccia
-
Publication number: 20130255997Abstract: Process for producing conductive and/or piezoresistive traces in a non-conductive polymeric substrate through laser irradiation, characterised in that said substrate is a composite polymeric material, comprising the matrix of a polymer not susceptible to carbonisation through laser irradiation and a dispersed phase comprising carbon nano fibres and/or nanotubes.Type: ApplicationFiled: October 26, 2011Publication date: October 3, 2013Applicants: R.T.M. S.p.A.-ISTITUTO PER LE RICERCHE DI TECNOLOGIA MECCANICA E L'AUTOMAZIONE S.p.A., C.R.F. SOCIETA' CONSORTILE PER AZIONIInventors: Adriano Zecchina, Fabrizio Bardelli, Serena Bertarione, Giuseppe Caputo, Paolo Castelli, Federico Cesano, Pierluigi Civera, Danilo Demarchi, Roberta Galli, Gianfranco Innocenti, Domenica Scarano, Antonino Veca, Marco Zanetti
-
Publication number: 20120004391Abstract: Cyanine-type fluorescent dyes modified with an alkynyl linker arm of formula (I), suitable for the conjugation of biomolecules, such as for example nucleosides, nucleotides, oligonucleotides, nucleic acids, proteins, peptides, vitamins and hormones. A method and intermediates for the synthesis of the alkynyl cyanines of the invention are also described, as well as alkynyl cyanine-biomolecule conjugates and methods for preparing thereof. The alkynyl cyanines can be advantageously used as markers for biomolecules or as quenchers.Type: ApplicationFiled: January 24, 2011Publication date: January 5, 2012Inventor: Giuseppe CAPUTO
-
Publication number: 20110201784Abstract: A silane-modified cyanine of Formula (I) includes the valence tautomers thereof: wherein R1 is a linear, saturated or unsaturated alkyl chain, having 1 to 30 carbon atoms, wherein one or more carbon atoms are optionally substituted by a 4-, 5- or 6-membered aromatic or non aromatic cyclic grouping of carbon atoms; R8 and R9 are independently selected from the group consisting of —OCH3, —OCH2CH3, —OCH2CH2CH3, —OCH(CH3)2, —OCH2CH2OCH3, —Cl, —Br, —I, Formula (II), Formula (III), —N(CH3)2, Formula (IV), Formula (V), methyl, ethyl, propyl, isopropyl. The synthesis method and the use as a fluorescent marker are for inorganic solid supports, for example silica nanoparticles, and/or for biomolecules such as peptides, antibodies, DNA, RNA, etc.Type: ApplicationFiled: October 21, 2009Publication date: August 18, 2011Inventors: Giuseppe Caputo, Ivana Miletto, Chiara Alessandra Bertolino, Gianmario Martra, Salvatore Coluccia
-
Publication number: 20110118438Abstract: Cyanine-type fluorescent dyes modified with an alkynyl linker arm of formula (I), suitable for the conjugation of biomolecules, such as for example nucleosides, nucleotides, oligonucleotides, nucleic acids, proteins, peptides, vitamins and hormones. A method and intermediates for the synthesis of the alkynyl cyanines of the invention are also described, as well as alkynyl cyanine-biomolecule conjugates and methods for preparing thereof. The alkynyl cyanines can be advantageously used as markers for biomolecules or as quenchers.Type: ApplicationFiled: January 24, 2011Publication date: May 19, 2011Inventor: Giuseppe CAPUTO
-
Patent number: 7892297Abstract: Cyanine-type fluorescent dyes modified with an alkynyl linker arm of formula (I), suitable for the conjugation of biomolecules, such as for example nucleosides, nucleotides, oligonucleotides, nucleic acids, proteins, peptides, vitamins and hormones. A method and intermediates for the synthesis of the alkynyl cyanines of the invention are also described, as well as alkynyl cyanine-biomolecule conjugates and methods for preparing thereof. The alkynyl cyanines can be advantageously used as markers for biomolecules or as quenchers.Type: GrantFiled: August 11, 2004Date of Patent: February 22, 2011Assignee: Cyanine Technologies S.p.A.Inventor: Giuseppe Caputo
-
Patent number: 7750157Abstract: The present invention relates to luminescent compounds having a functionalised linker arm, their synthesis and use in bioconjugation and labelling of biomolecules, such as for example nucleosides, nucleotides, nucleic acids (DNA, RNA or PNA) and proteins, as well as their use in the execution of in vitro and in vivo analytic and diagnostic assays.Type: GrantFiled: June 1, 2005Date of Patent: July 6, 2010Assignee: Universita' Degli Studi di TorinoInventors: Giuseppe Caputo, Roberto Gobetto, Guido Viscardi
-
Publication number: 20070231818Abstract: The present invention relates to luminescent compounds having a functionalised linker arm, their synthesis and use in bioconjugation and labelling of biomolecules, such as for example nucleosides, nucleotides, nucleic acids (DNA, RNA or PNA) and proteins, as well as their use in the execution of in vitro and in vivo analytic and diagnostic assays.Type: ApplicationFiled: June 1, 2005Publication date: October 4, 2007Inventors: Giuseppe Caputo, Roberto Gobetto, Guido Viscardi
-
Publication number: 20060230554Abstract: Cyanine-type fluorescent dyes modified with an alkynyl linker arm of formula (I), suitable for the conjugation of biomolecules, such as for example nucleosides, nucleotides, oligonucleotides, nucleic acids, proteins, peptides, vitamins and hormones. A method and intermediates for the synthesis of the alkynyl cyanines of the invention are also described, as well as alkynyl cyanine-biomolecule conjugates and methods for preparing thereof. The alkynyl cyanines can be advantageously used as markers for biomolecules or as quenchers.Type: ApplicationFiled: August 11, 2004Publication date: October 19, 2006Inventor: Giuseppe Caputo
-
Publication number: 20050245734Abstract: A process for preparing an asymmetrical indocyanine dye comprising the steps of: a) reacting a first quaternised indolenine or substituted indolenine with a compound of the formula (II) or hydrochloride thereof, wherein n is 0 or 1 Ph is phenyl or substituted phenyl X is hydrogen, halogen or alkyl, preferably chlorine, in a solvent selected from the group consisting of acetic acid, acetic anhydride and mixtures thereof in the presence of acetyl chloride, to obtain an intermediate hemicyanine, and b) further reacting said intermediate hemicyanine with a second quaternised indolenine or substituted indolenine different from said first indolenine.Type: ApplicationFiled: April 12, 2004Publication date: November 3, 2005Inventors: Giuseppe Caputo, Leopoldo Ciana
-
Patent number: 6747159Abstract: A symmetric cyanine of the formula: wherein: X is selected from the group consisting of O, S and C(CH3)2; W represents non-metal atoms required to form a benzo-condensed or a naphto-condensed ring; R1 is selected from the group consisting of (CH2)nCH3, (CH2)nSO3− and (CH2)nSO3H, wherein n is an integer selected from 0 to 6 when R1 is (CH2)nCH3, and n is an integer selected from 3 to 6 when R1 is (CH2)nSO3− or (CH2)nSO3H; R2 and R3 are independently selected from the group consisting of H, a sulphonic moiety and a sulphonate moiety and Q is a substituted polymethine bridge.Type: GrantFiled: January 2, 2002Date of Patent: June 8, 2004Inventors: Giuseppe Caputo, Leopoldo Della Ciana
-
Patent number: 6740755Abstract: A process for preparing an asymmetrical indocyanine dye comprising the steps of: a) reacting a first quaternised indolenine or substituted indolenine with a compound of the formula (II) or hydrochloride thereof, wherein n is 0 or 1 Ph is phenyl or substituted phenyl X is hydrogen, halogen or alkyl, preferably chlorine, in a solvent selected from the group consisting of acetic acid, acetic anhydride and mixtures thereof in the presence of acetyl chloride, to obtain an intermediate hemicyanine, and b) further reacting said intermediate hemicyanine with a second quaternised indolenine or substituted indolenine different from said first indolenine.Type: GrantFiled: November 27, 2001Date of Patent: May 25, 2004Inventors: Giuseppe Caputo, Leopoldo Della Ciana
-
Patent number: 6731379Abstract: A device for determining the concentration of heparin in a fluid sample comprising: a container for holding the fluid sample; a container for holding the dye solution; a mixer for mixing the fluid sample and the dye solution; an illumination source for illuminating a mixture comprising the fluid sample and the dye solution with electromagnetic radiation having a substantially continuous range of wavelengths in the visible range; a detector for detecting the absorption spectrum of the mixture within the substantially continuous range of wavelengths; a recorder for recording the absorption spectrum of the mixture within the substantially continuous range of wavelengths; and a calculator for calculating a spectral parameter.Type: GrantFiled: August 5, 2003Date of Patent: May 4, 2004Assignee: Dideco S.p.A.Inventors: Giuseppe Caputo, Raffaele Castelli, Elena Comoglio, Leopoldo Della Ciana, Arnaldo Giannetti