Patents by Inventor Giuseppe CELESTI

Giuseppe CELESTI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Different levels in blood cell samples of EMT-markers for the diagnosis of cancer, in particular of colorectal (CRC) and pancreatic (PC) cancer
    Patent number: 10907210
    Abstract: The present invention concerns a method for determining if a subject is affected by a colorectal or pancreatic cancer or for determining the stage and/or the progression of a colorectal cancer. By measuring the presence of a panel of m RNAs encoding for transcription factors/genes involved in epithelial to mesenchymal transition in a blood sample, wherein different mRNA levels of a set of genes comprising TWIST1, SLUG, ZEB2, ZEB1 and CDH1, are indicative of colorectal cancer or pancreatic cancer diagnosis, and/or of colorectal cancer stage at diagnosis, and/or of CRC metastatic progression after surgery. The invention concerns also the use of kits to work the method.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: February 2, 2021
    Assignee: HUMANITAS MIRASOLE S.P.A.
    Inventors: Luigi Laghi, Giuseppe Celesti
  • DIFFERENT LEVELS IN BLOOD CELL SAMPLES OF EMT-MARKERS FOR THE DIAGNOSIS OF CANCER, IN PARTICULAR OF COLORECTAL (CRC) AND PANCREATIC (PC) CANCER
    Publication number: 20160312296
    Abstract: The present invention concerns a method for determining if a subject is affected by a colorectal or pancreatic cancer or for determining the stage and/or the progression of a colorectal cancer. By measuring the presence of a panel of m RNAs encoding for transcription factors/genes involved in epithelial to mesenchymal transition in a blood sample, wherein different mRNA levels of a set of genes comprising TWIST1, SLUG, ZEB2, ZEB1 and CDH1, are indicative of colorectal cancer or pancreatic cancer diagnosis, and/or of colorectal cancer stage at diagnosis, and/or of CRC metastatic progression after surgery. The invention concerns also the use of kits to work the method.
    Type: Application
    Filed: December 16, 2014
    Publication date: October 27, 2016
    Inventors: Luigi LAGHI, Giuseppe CELESTI