Patents by Inventor Giuseppe Ciaramella

Giuseppe Ciaramella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sexually transmitted disease vaccines
    Patent number: 10493143
    Abstract: The disclosure relates to sexually transmitted disease ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: December 3, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • INFLUENZA VACCINE
    Publication number: 20190336595
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines comprising polynucleotide molecules encoding one or more influenza antigens, such as hemagglutinin antigens.
    Type: Application
    Filed: November 10, 2017
    Publication date: November 7, 2019
    Applicant: ModernaTX, Inc.
    Inventor: Giuseppe Ciaramella
  • HUMAN CYTOMEGALOVIRUS RNA VACCINES
    Publication number: 20190321464
    Abstract: The disclosure describes HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: June 24, 2019
    Publication date: October 24, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • Zika RNA vaccines
    Patent number: 10449244
    Abstract: Aspects of the disclosure describe compositions that comprise RNA polynucleotides having an open reading frame encoding one or more Zika virus antigens. Methods for preparing and using the compositions are also described.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: October 22, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu
  • HUMAN CYTOMEGALOVIRUS VACCINE
    Publication number: 20190314493
    Abstract: The disclosure relates to HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: April 19, 2019
    Publication date: October 17, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John
  • Human cytomegalovirus RNA vaccines
    Patent number: 10383937
    Abstract: HCMV ribonucleic acid (RNA) vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: June 12, 2018
    Date of Patent: August 20, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Shinu John, Kambiz Mousavi
  • HPIV3 RNA VACCINES
    Publication number: 20190240317
    Abstract: The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: March 28, 2019
    Publication date: August 8, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • HMPV RNA VACCINES
    Publication number: 20190216917
    Abstract: The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Application
    Filed: March 28, 2019
    Publication date: July 18, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • HIGH POTENCY IMMUNOGENIC COMPOSITIONS
    Publication number: 20190211065
    Abstract: Provided herein, in some embodiments, are immunogenic compositions that include a cationic lipid nanoparticle (LNP) encapsulating messenger ribonucleic acid (mRNA) having an open reading frame encoding a viral, bacterial or parasitic antigen, a pan HLA DR-binding epitope (PADRE), and a 5? terminal cap modified to increase mRNA translation efficiency.
    Type: Application
    Filed: March 22, 2019
    Publication date: July 11, 2019
    Applicant: ModernaTX, Inc.
    Inventor: Giuseppe Ciaramella
  • Combination PIV3/hMPV RNA vaccines
    Patent number: 10272150
    Abstract: The disclosure relates to respiratory virus ribonucleic acid (RNA) vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: April 30, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • High potency immunogenic zika virus compositions
    Patent number: 10273269
    Abstract: Provided herein, in some embodiments, are Zika Virus immunogenic compositions that include a cationic lipid nanoparticle (LNP) encapsulating messenger ribonucleic acid (mRNA) having an open reading frame encoding Zika Virus antigens, a pan HLA DR-binding epitope (PADRE), and a 5? terminal cap modified to increase mRNA translation efficiency.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: April 30, 2019
    Assignee: ModernaTX, Inc.
    Inventor: Giuseppe Ciaramella
  • ZIKA VIRUS MRNA VACCINES
    Publication number: 20190099481
    Abstract: Provided herein, in some embodiments, are Zika virus RNA vaccines and methods of producing an antigen-specific immune response in a subject.
    Type: Application
    Filed: September 14, 2018
    Publication date: April 4, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu
  • Chikagunya virus RNA vaccines
    Patent number: 10238731
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: March 26, 2019
    Assignee: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks, Sayda Mahgoub Elbashir
  • INFECTIOUS DISEASE VACCINES
    Publication number: 20190060438
    Abstract: Aspects of the disclosure relate to nucleic acid vaccines. The vaccines include one or more RNA polynucleotides having an open reading frame encoding one or more Chikungunya antigen(s), one or more Zika virus antigens, and one or more Dengue antigens. Methods for preparing and using such vaccines are also described.
    Type: Application
    Filed: July 21, 2016
    Publication date: February 28, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Kapil Bahl, Tal Zaks, Sunny Himansu
  • NUCLEIC ACID VACCINES
    Publication number: 20190015501
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Application
    Filed: September 27, 2018
    Publication date: January 17, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang
  • CHIKUNGUNYA VIRUS RNA VACCINES
    Publication number: 20190008947
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks, Sayda Mahgoub Elbashir
  • CONCATEMERIC PEPTIDE EPITOPE RNAS
    Publication number: 20190008938
    Abstract: The invention relates to concatemeric peptide epitope RNAs, as well as methods and compositions thereof. mRNA vaccines are also provided according to the invention, including cancer vaccines.
    Type: Application
    Filed: July 29, 2016
    Publication date: January 10, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Eric Yi-Chun Huang, Nicholas Valiante, Tal Zaks
  • NUCLEIC ACID VACCINES
    Publication number: 20190008948
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Application
    Filed: July 16, 2018
    Publication date: January 10, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang
  • ZIKA VIRUS RNA VACCINES
    Publication number: 20190008946
    Abstract: The disclosure relates to tropical diseases such as viral mosquito borne illnesses and the treatment thereof. The invention includes ribonucleic acid vaccines and combination vaccines, as well as methods of using the vaccines and compositions comprising the vaccines for treating and preventing tropical disease.
    Type: Application
    Filed: September 20, 2018
    Publication date: January 10, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Sunny Himansu, Eric Yi-Chun Huang, Tal Zaks
  • NUCLEIC ACID VACCINES
    Publication number: 20190000959
    Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use ribonucleic acid vaccines (NAVs) comprising polynucleotide molecules encoding one or more antigens.
    Type: Application
    Filed: July 27, 2018
    Publication date: January 3, 2019
    Applicant: ModernaTX, Inc.
    Inventors: Giuseppe Ciaramella, Axel Bouchon, Eric Yi-Chun Huang