Patents by Inventor Giuseppe DeNicolao

Giuseppe DeNicolao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120245556
    Abstract: A method, system and computer program product for correcting a nominal treatment strategy of a subject with diabetes. The method, system and computer program product may be configured for providing input whereby the input may include: open-loop therapy settings for the subject, data about glycemic state of the subject; and (optionally) data about meals and/or exercise of the subject. The method, system and computer program product may be configured for providing output, whereby the out-put may include an adjustment (correction) to the open-loop therapy settings for the subject for insulin delivery to the subject.
    Type: Application
    Filed: August 31, 2010
    Publication date: September 27, 2012
    Inventors: Boris P. Kovatchev, Giuseppe DeNicolao, Lalo Magni, Chiara Dalla Man, Claudio Cobelli
  • Publication number: 20050143927
    Abstract: The present invention relates to a method for estimating or predicting anti-tumor activity of a compound and for estimating or predicting the tumor growth in mammals; the estimation comprises a) measuring the tumor weight in time; b) measuring the concentration of the compound in time; c) calculating kinetic parameters of the tumor growth: -a parameter (L0), representative of the portion of tumor cells present at the instant t0=0 that succeeds in taking root and in starting tumor cells proliferation in the mammals; -an index (?0) of the production rate of tumor cells during an exponential phase of tumor growth; -an index (?1) of tumor cells mass produced in the time unit during a linear phase of the tumor growth; and pharmacodynamic parameters: -an index (K1) of tumor cells death rate; -an index (K2) of the potency of the compound; and d) calculating tumor growth curves.
    Type: Application
    Filed: September 15, 2004
    Publication date: June 30, 2005
    Applicants: Pharmacia Italia S.p.A., Universita Degli Studi Di Pavia
    Inventors: Cristiano Cammia, Giuseppe DeNicolao, Italo Poggesi, Maurizio Rocchetti