Patents by Inventor Giuseppe Marazzi

Giuseppe Marazzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GADOLINIUM BEARING PCTA-BASED CONTRAST AGENTS
    Publication number: 20210196840
    Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutamic glutaric acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.
    Type: Application
    Filed: March 11, 2021
    Publication date: July 1, 2021
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Roberta NAPOLITANO, Luciano LATTUADA, Zsolt BARANYAI, Nicole GUIDOLIN, Giuseppe MARAZZI
  • Gadolinium bearing PCTA-based contrast agents
    Patent number: 10973934
    Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutaric acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.
    Type: Grant
    Filed: August 6, 2019
    Date of Patent: April 13, 2021
    Assignee: BRACCO IMAGING S.P.A.
    Inventors: Roberta Napolitano, Luciano Lattuada, Zsolt Baranyai, Nicole Guidolin, Giuseppe Marazzi
  • GADOLINIUM BEARING PCTA-BASED CONTRAST AGENTS
    Publication number: 20200376145
    Abstract: The present invention relates to the RRR/SSS pair of enantiomers of the of Gd(PCTA-tris-glutamic acid), the single enantiomers of the pair, the pharmaceutically acceptable salts thereof, their amide derivatives, and compositions comprising at least 50% of these compounds.
    Type: Application
    Filed: August 6, 2019
    Publication date: December 3, 2020
    Applicant: BRACCO IMAGING S.P.A.
    Inventors: Roberta NAPOLITANO, Luciano LATTUADA, Zsolt BARANYAI, Nicole GUIDOLIN, Giuseppe MARAZZI
  • Aminooxime derivatives of 2- and/or 4-substituted androstanes and androstenes as medicaments for cardiovascular disorders
    Patent number: 8664210
    Abstract: New aminooxime derivatives at position 3 of 2- and/or 4-substituted androstanes and androstenes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: March 4, 2014
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Alberto Cerri, Giuseppe Bianchi, Giorgio Fedrizzi, Patrizia Ferrari, Mauro Gobbini, Marco Torri, Giuseppe Marazzi, Walter Cabri
  • Crystalline form II of 7-(dimethoxy-methyl) camptothecin, its use as intermediate and products obtained therefrom
    Patent number: 8269007
    Abstract: This invention relates to a process for preparing a crystalline form of (4S)-11(dimethoxymethyl)-4-ethyl-4-hydroxy-1H-pyrano[3?4?:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, also named 7-(dimethoxy-methyl)camptothecin). With the provision of a particular crystallization step, in appropriate way, a new crystalline form of the above compound is obtained. The process for the preparation of the polymorph Form II comprises transforming camptothecin to the corresponding 7-(dimethoxy-methyl)-camptothecin, and crystallizing from methanol.
    Type: Grant
    Filed: July 22, 2008
    Date of Patent: September 18, 2012
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite SpA
    Inventors: Walter Cabri, Mauro Marzi, Fabrizio Giorgi, Elena Badaloni, Silvia Armaroli, Giuseppe Marazzi
  • AMINOOXIME DERIVATIVES OF 2- AND/OR 4-SUBSTITUTED ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS
    Publication number: 20100324003
    Abstract: New aminooxime derivatives at position 3 of 2- and/or 4-substituted androstanes and androstenes, processes for their preparation, and to pharmaceutical compositions containing them for the treatment of cardiovascular disorders, such as heart failure and hypertension. In particular compounds having the general formula (I) are described, where the radicals have the meanings described in detail in the application.
    Type: Application
    Filed: September 18, 2008
    Publication date: December 23, 2010
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Alberto Cerri, Giuseppe Bianchi, Giorgio Fedrizzi, Patrizia Ferrari, Mauro Gobbini, Giuseppe Marazzi, Marco Torri, Walter Cabri
  • CRYSTALLINE FORM II OF 7-(DIMETHOXY-METHYL) CAMPTOTHECIN, ITS USE AS INTERMEDIATE AND PRODUCTS OBTAINED THEREFROM
    Publication number: 20100249414
    Abstract: This invention relates to a process for preparing a crystalline form of (4S)-11-(dimethoxymethyl)-4-ethyl-4-hydroxy-1H-pyrano[3?,4?:6,7]indolizino[1,2-b]qui-noline-3,14(4H,12H)-dione (also named 7-(dimethoxy-methyl)camptothecin). With the provision of a particular crystallization step, in appropriate way, a new crystalline form of the above compound is obtained. The process for the preparation of the polymorph Form II comprises transforming camptothecin to the corresponding 7-(dimethoxy-methyl)-camptothecin, and crystallizing it from methanol.
    Type: Application
    Filed: July 22, 2008
    Publication date: September 30, 2010
    Applicant: SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A.
    Inventors: Walter Cabri, Mauro Marzi, Fabrizio Giorgi, Elena Badaloni, Silvia Armaroli, Giuseppe Marazzi