Patents by Inventor Giuseppe MERLINO

Giuseppe MERLINO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220289851
    Abstract: The present disclosure relates generally to the fields of immunology and molecular biology. More specifically, provided herein are pharmaceutical combinations comprising (A) antibodies, or antigen-binding portions thereof, directed against LY75, and (B) a second anti-cancer entity; nucleic acids encoding antibody combinations; methods for preparing antibody combinations; and methods for the treatment of diseases, such as cancers mediated by LY75 expression or activity.
    Type: Application
    Filed: May 3, 2022
    Publication date: September 15, 2022
    Applicant: BERLIN-CHEMIE AG
    Inventors: Monica BINASCHI, Mario BIGIONI, Giuseppe MERLINO, Cecilia SIMONELLI, Francesco BERTONI, Andrea PELLACANI
  • Patent number: 11365258
    Abstract: The present disclosure relates generally to the fields of immunology and molecular biology. More specifically, provided herein are pharmaceutical combinations comprising (A) antibodies, or antigen-binding portions thereof, directed against LY75, and (B) a second anti-cancer entity; nucleic acids encoding antibody combinations; methods for preparing antibody combinations; and methods for the treatment of diseases, such as cancers mediated by LY75 expression or activity.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: June 21, 2022
    Assignee: BERLIN-CHEMIE AG
    Inventors: Monica Binaschi, Mario Bigioni, Giuseppe Merlino, Cecilia Simonelli, Francesco Bertoni, Andrea Pellacani
  • Publication number: 20210113690
    Abstract: The present disclosure relates generally to the fields of immunology and molecular biology. More specifically, provided herein are pharmaceutical combinations comprising (A) antibodies, or antigen-binding portions thereof, directed against LY75, and (B) Venetoclax; methods for preparing pharmaceutical combinations; and methods for the treatment of diseases, such as cancers mediated by LY75 expression or activity.
    Type: Application
    Filed: June 13, 2019
    Publication date: April 22, 2021
    Applicant: BERLIN-CHEMIE AG
    Inventors: Giuseppe MERLINO, Mario BIGIONI, Monica BINASCHI, Andrea PELLACANI
  • Publication number: 20210015826
    Abstract: The present invention relates to new combinations of antitumour or anticancer agents for the tumour combination therapy, pharmaceutical compositions intended for combined use and kit containing compositions of different antitumour agents for combined use. In particular the present invention relates to combinations of various tumour agents with the PBK-Class I inhibitor 5-(7-methanesulfonyl-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-il-amine or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: March 28, 2019
    Publication date: January 21, 2021
    Applicant: BERLIN-CHEMIE AG
    Inventors: Giuseppe MERLINO, Mario BIGIONI, Monica BINASACHI, Andrea PELLACANI
  • Publication number: 20200040086
    Abstract: The present disclosure relates generally to the fields of immunology and molecular biology. More specifically, provided herein are pharmaceutical combinations comprising (A) antibodies, or antigen-binding portions thereof, directed against LY75, and (B) a second anti-cancer entity; nucleic acids encoding antibody combinations; methods for preparing antibody combinations; and methods for the treatment of diseases, such as cancers mediated by LY75 expression or activity.
    Type: Application
    Filed: September 3, 2018
    Publication date: February 6, 2020
    Applicant: BERLIN-CHEMIE AG
    Inventors: Monica BINASCHI, Mario BIGIONI, Giuseppe MERLINO, Cecilla SIMONELLI, Francesco BERTONI