Patents by Inventor Giuseppe PALLANZA

Giuseppe PALLANZA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of sofosbuvir
    Patent number: 10112967
    Abstract: A process for the synthesis of Sofosbuvir is provided comprising the steps of selectively mono-deacetylating a compound of formula (V) enzymatically using a resin supported lipase B derived from Candida Antarctica to obtain a compound formula (IV), then converting the compound of formula (IV) to a compound of formula (II) by reacting the compound of formula (IV) with a compound of formula (III), and then converting the compound of formula (II) to Sofosbuvir of formula (I) by deacetylation reaction.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: October 30, 2018
    Assignee: HC-PHARMA AG
    Inventors: Mauro Gaboardi, Giuseppe Pallanza, Marco Baratella, Graziano Castaldi, Marta Castaldi
  • Process for the synthesis of Dapsone and its intermediates
    Patent number: 9845289
    Abstract: A process for the synthesis of Dapsone and intermediates thereof are described.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: December 19, 2017
    Assignee: SEEGPHARM SA
    Inventors: Marco Baratella, Graziano Castaldi, Marta Castaldi, Mauro Gaboardi, Giuseppe Pallanza
  • PROCESS FOR THE PREPARATION OF SOFOSBUVIR
    Publication number: 20170247404
    Abstract: The present invention relates to a process for the synthesis of Sofosbuvir.
    Type: Application
    Filed: November 22, 2016
    Publication date: August 31, 2017
    Inventors: Mauro GABOARDI, Giuseppe PALLANZA, Marco BARATELLA, Graziano CASTALDI, Marta CASTALDI
  • PROCESS FOR THE SYNTHESIS OF DAPSONE AND ITS INTERMEDIATES
    Publication number: 20170217883
    Abstract: A process for the synthesis of Dapsone and intermediates thereof are described.
    Type: Application
    Filed: July 29, 2015
    Publication date: August 3, 2017
    Inventors: Marco BARATELLA, Graziano CASTALDI, Marta CASTALDI, Mauro GABOARDI, Giuseppe PALLANZA
  • Process for the preparation of erlotinib
    Patent number: 9428468
    Abstract: A process for the preparation of Erlotinib is disclosed in which the compound of formula (II) Is reacted with the compound of formula (III) in the presence of trifluoroacetic acid and formamidine acetate, in an aprotic solvent, and the reaction product is subsequently treated with a source of hydrochloric acid in a suitable solvent to give Erlotinib hydrochloride.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: August 30, 2016
    Assignee: CERBIOS-PHARMA SA
    Inventors: Marco Baratella, Giuseppe Pallanza, Mauro Gaboardi, Graziano Castaldi
  • PROCESS FOR THE PREPARATION OF ERLOTINIB
    Publication number: 20160115137
    Abstract: A process for the preparation of Erlotinib is disclosed in which the compound of formula (II) Is reacted with the compound of formula (III) and the reaction product is subsequently treated with a source of hydrochloric acid in a suitable solvent to give Erlotinib hydrochloride.
    Type: Application
    Filed: October 27, 2015
    Publication date: April 28, 2016
    Inventors: Marco BARATELLA, Giuseppe PALLANZA, Mauro GABOARDI, Graziano CASTALDI
  • INTERMEDIATES USEFUL FOR THE PREPARATION OF SAXAGLIPTIN
    Publication number: 20160107992
    Abstract: Intermediates useful for the synthesis of saxagliptin and their preparationare described.
    Type: Application
    Filed: June 18, 2014
    Publication date: April 21, 2016
    Inventors: Graziano CASTALDI, Giuseppe PALLANZA, Mauro GABOARDI, Marta CASTALDI