Patents by Inventor Giuseppe Pantaleo

Giuseppe Pantaleo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified Immunization Vectors
    Publication number: 20170246280
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: October 10, 2016
    Publication date: August 31, 2017
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mario Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias Haddad, James Tartaglia
  • Immunological Reagents
    Publication number: 20170226210
    Abstract: This disclosure relates to binding agents with specificity for programmed cell death 1 (PD-1) and to methods for using the same to treat, prevent and/or ameliorate an infectious disease (e.g., human immunodeficiency virus (HIV)), cancer and/or autoimmunity.
    Type: Application
    Filed: August 5, 2015
    Publication date: August 10, 2017
    Applicant: MabQuest SA
    Inventors: Giuseppe Pantaleo, Craig Fenwick
  • Immunological Reagents
    Publication number: 20170166642
    Abstract: This disclosure relates to binding agents with specificity for programmed cell death 1 (PD-1) and to methods for using the same to treat, prevent and/or ameliorate an infectious disease (e.g., human immunodeficiency virus (HIV)), cancer and/or autoimmunity. In addition, this disclosure identifies a novel binding patch (“P2”) on PD-1 that is linked with a previously unidentified functional activity of PD-1 that is distinct from the interaction site involved with either the PD-L1 or PD-L2 ligands. Furthermore, we demonstrate that antibodies that interact with this region of PD-1 are able to act as antagonists of PD-1 and that this antagonism is further enhanced with the addition of antibodies that act through the blockade of the PD-1/PD-L1/L2 interaction.
    Type: Application
    Filed: September 22, 2016
    Publication date: June 15, 2017
    Applicant: MabQuest SA
    Inventors: Giuseppe Pantaleo, Craig Fenwick
  • Modified immunization vectors
    Patent number: 9670506
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Grant
    Filed: April 29, 2010
    Date of Patent: June 6, 2017
    Assignees: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS, ACADEMISCH ZIKENHUIS LEIDEN, CENTRE HOSPITALIER UNIVERSITAIRE VAUDOIS, UNIVERSITE DE MONTREAL, ARIZONA BOARD OF REGENTS, SANOFI PASTEUR LIMITED
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mariano Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias Haddad, James Tartaglia
  • Immunological Compositions
    Publication number: 20170065710
    Abstract: The disclosure relates to immunological compositions for vaccinating human beings against infection by the Human Immunodeficiency Virus (HIV).
    Type: Application
    Filed: February 11, 2016
    Publication date: March 9, 2017
    Inventors: James Tartaglia, Giuseppe Pantaleo, Alexandri Harari
  • Methods for Typing HLA Alleles
    Publication number: 20160186265
    Abstract: This disclosure relates to the typing of human leucocyte antigen (HLA) alleles. More particularly, the present invention relates to HLA typing as a method of identify patients at risk of a hypersensitivity reaction to drugs such as abacavir and/or to diagnose disease (e.g., Behçet's disease).
    Type: Application
    Filed: August 14, 2014
    Publication date: June 30, 2016
    Inventors: Cyril Andre, Giuseppe Pantaleo
  • Methods for differentiating between disease states
    Patent number: 9146236
    Abstract: This disclosure relates to methods for differentiating between mammals having active and latent Tuberculosis disease, by determining the percentage of polyfunctional CD4+ T-cells expressing TNF-alpha, IFN-gamma, and IL-2, or by determining expression of IL-17.
    Type: Grant
    Filed: December 22, 2011
    Date of Patent: September 29, 2015
    Inventors: Giuseppe Pantaleo, Alexandre Harari, Matthieu Perreau
  • Methods for Differentiating Between Disease States
    Publication number: 20130338059
    Abstract: This disclosure relates to methods for differentiating between mammals having active and latent Tuberculosis disease, by determining the percentage of polyfunctional CD4+ T-cells expressing TNF-alpha, IFN-gamma, and IL-2, or by determining expression of IL-17.
    Type: Application
    Filed: December 22, 2011
    Publication date: December 19, 2013
    Applicant: Centre Hospitalier Universitaire Vaudois
    Inventors: Giuseppe Pantaleo, Alexandre Harari, Matthieu Perreau
  • MODIFIED IMMUNIZATION VECTORS
    Publication number: 20120328653
    Abstract: The disclosure relates to recombinant vectors and methods for using the same. In certain embodiments, the recombinant vectors are immunogenic.
    Type: Application
    Filed: April 29, 2010
    Publication date: December 27, 2012
    Inventors: Giuseppe Pantaleo, Thierry Calandra, Alexandre Harari, Thierry Roger, Mariano Esteban, Bertram Jacobs, Karen Kibler, Cornelius Melief, Rafick-Pierre Sekaly, Elias Haddad, James Tartaglia
  • Immunological compositions
    Publication number: 20090060947
    Abstract: The disclosure relates to immunological compositions for vaccinating human beings against infection by the Human Immunodeficiency Virus (HIV).
    Type: Application
    Filed: May 18, 2007
    Publication date: March 5, 2009
    Applicant: SANOFI PASTEUR, INC.
    Inventors: James Tartaglia, Alexander Harari, Giuseppe Pantaleo