Patents by Inventor Giuseppe Prota

Giuseppe Prota has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6313313
    Abstract: Water soluble, cationic compounds useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of 5,6-dihydroxyindole-2-carboxylic acid or its N-substituted derivatives and a quaternary salt containing a reactive amino or hydroxyl group, and polymers from such compounds obtained by oxidative polymerization.
    Type: Grant
    Filed: September 18, 1998
    Date of Patent: November 6, 2001
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gottfried Wenke, Giuseppe Prota
  • Patent number: 6160127
    Abstract: A process for the preparation of 5,6-disubstituted indoles in which a 4-5-disubstituted-2,.beta.-nitrostyrene is subjected to a reductive cyclization in the presence of a water soluble dithionite salt.
    Type: Grant
    Filed: July 15, 1998
    Date of Patent: December 12, 2000
    Assignee: Bristol-Myers Squibb Company
    Inventors: Giuseppe Prota, Gottfried Wenke
  • Patent number: 5961991
    Abstract: Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
    Type: Grant
    Filed: June 11, 1997
    Date of Patent: October 5, 1999
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gottfried Wenke, Giuseppe Prota
  • Patent number: 5827330
    Abstract: Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: October 27, 1998
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Gottfried Wenke, Giuseppe Prota
  • Patent number: 5792220
    Abstract: The present invention concerns improved processes for dyeing keratinous fibers especially hair on the human scalp using a two-step oxidation process for the oxidation of the melanin precursors 5,6-dihydroxyindoline (DHIN), 5,6-dihydroxyindole (DHI), and derivatives thereof such as 5,6-dihydroxyindole-2-carboxylic acid (DHICA).
    Type: Grant
    Filed: May 16, 1997
    Date of Patent: August 11, 1998
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gottfried Wenke, Giuseppe Prota
  • Patent number: 5704949
    Abstract: The present invention is directed to the preparation of an aqueous hair dyeing composition containing an effective hair dyeing amount--at least 2 mg/ml--5,6-dihydroxyindole (DHI). An aqueous hair dyeing composition is produced by reacting under essentially anaerobic conditions dopa or a salt thereof with an alkali metal ferricyanide oxidant in an aqueous reaction medium to obtain dopachrome, and permitting the dopachrome to undergo rearrangement in the aqueous medium to form 5,6-dihydroxyindole, said rearrangement being conducted in the substantial absence of oxidant, the aqueous medium being buffered by sufficient buffering agent to maintain a pH of from about 4.5 to about 9 for the reaction medium throughout the series of reactions that take place thereafter, removing the ferrocyanide species present in the aqueous system, and lastly, charging the composition into a suitable container.
    Type: Grant
    Filed: February 16, 1996
    Date of Patent: January 6, 1998
    Assignee: Clairol Incorporated
    Inventors: Giuseppe Prota, Gottfried Wenke, Leszek Wolfram
  • Patent number: 5702712
    Abstract: Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.
    Type: Grant
    Filed: December 6, 1995
    Date of Patent: December 30, 1997
    Assignee: Clairol, Incorporated
    Inventors: Gottfried Wenke, Giuseppe Prota
  • Patent number: 5686084
    Abstract: The specification describes water soluble, cationic products useful as hair colorants or for skin care obtained by oxidative polymerization of a 5,6-dihydroxyindole-2-quaternary amides or esters, as well as compositions containing the same, methods of using the same in compositions to color hair or treat skin and intermediates for producing the products.
    Type: Grant
    Filed: December 6, 1995
    Date of Patent: November 11, 1997
    Assignee: Clairol Incorporated
    Inventors: Gottfried Wenke, Giuseppe Prota
  • Patent number: 5628799
    Abstract: A process for dyeing hair by preparing and applying to the hair an aqueous reaction medium comprising a dopa species, a reactive direct dye and an oxidant, said aqueous reaction medium optionally containing at least one hair dyeing agent selected from the group consisting of primary intermediates and couplers and also containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 13, 1997
    Assignee: Clairol Incorporated
    Inventors: Gottfried Wenke, Giuseppe Prota
  • Patent number: 5545399
    Abstract: A composition for topical application to the skin in order to promote the repair of photo-damaged or aged skin and/or to reduce or prevent damaging effects of ultra-violet light on skin and/or to lighten the skin comprising a hydrocalchone of general structure: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3, which may be the same or different, represent H, --OH, --OR or --COR (where R is a C.sub.1-20 alkyl group);R.sub.4, R.sub.5, R.sub.6 and R.sub.7, which may be the same or different, represent H or --COR (where R is as herein before defined).Optional additional ingredients include sunscreens and other skin lightening skin lightening agents, particularly retinol or derivatives thereof.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: August 13, 1996
    Assignee: Chesebrough-Pond's USA Co.
    Inventors: Caroline M. Lee, Martin R. Green, Giuseppe Prota
  • Patent number: 5441542
    Abstract: A process for increasing the amount of melanin formation following hair dyeing by ferricyanide oxidation of a dopa species hair colorant utilizing a post-oxidant such as sodium periodate at a controlled pH and compositions and kits for use in the process.
    Type: Grant
    Filed: December 27, 1993
    Date of Patent: August 15, 1995
    Assignee: Clairol Incorporated
    Inventors: Giuseppe Prota, Gottfried Wenke
  • Patent number: 5346509
    Abstract: Process for dyeing human hair by the sequential treatment of the hair with a metal ion and particularly transition metal ion containing composition and with a dye composition containing 5,6-dihydroxyindole-2-carboxylic acid.
    Type: Grant
    Filed: April 14, 1993
    Date of Patent: September 13, 1994
    Assignee: Clairol Incorporated
    Inventors: Thomas M. Schultz, Keith C. Brown, Leszek J. Wolfram, Giuseppe Prota
  • Patent number: 5279617
    Abstract: A process for dyeing hair by preparing and thereafter applying to the hair an aqueous reaction medium comprising a substituted dopa species and an oxidant which is a ferricyanide salt, said aqueous reaction medium further containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation.
    Type: Grant
    Filed: July 13, 1992
    Date of Patent: January 18, 1994
    Assignee: Clairol Incorporated
    Inventors: Giuseppe Prota, Leszek Wolfram, Gottfried Wenke
  • Patent number: 5279618
    Abstract: A process for dyeing hair by preparing and thereafter applying to the hair an aqueous reaction medium comprising dopa and an oxidant, said aqueous reaction medium further containing at least one hair dyeing agent selected from the group consisting of primary intermediates and couplers and also containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation.
    Type: Grant
    Filed: July 31, 1992
    Date of Patent: January 18, 1994
    Assignee: Clairol Incorporated
    Inventors: Giuseppe Prota, Leszek Wolfram, Gottfried Wenke
  • Patent number: 5273550
    Abstract: A process for dyeing hair by preparing and thereafter applying to the hair an aqueous reaction medium comprising dopa and an oxidant selected from ferricyanide and permanganate salts, said aqueous reaction medium further containing a buffer to maintain the pH in the range from 6 to 10 during the reaction, and removing said aqueous reaction medium from the hair within about one hour following its preparation
    Type: Grant
    Filed: September 26, 1991
    Date of Patent: December 28, 1993
    Assignee: Clairol Incorporated
    Inventors: Giuseppe Prota, Leszek J. Wolfram, Gottfried Wenke
  • Patent number: 4904274
    Abstract: A process for coloring hair in which a functional metal ion and aminoalkyl or aminohydroxyalkyl catechols are used in combination or applied sequentially to dye the hair rapidly.
    Type: Grant
    Filed: May 12, 1988
    Date of Patent: February 27, 1990
    Assignee: Clairol Incorporated
    Inventors: Thomas M. Schultz, Leszek J. Wolfram, Keith C. Brown, Giuseppe Prota