Patents by Inventor Giuseppe Quadro

Giuseppe Quadro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5604254
    Abstract: The compound N-[N'acetyl(glycinyl)]-5-methoxytryptamine, of formula (I) ##STR1## exhibited markedly prolonged immunostimulating activity. The method of preparation and the method of use are described.
    Type: Grant
    Filed: December 1, 1995
    Date of Patent: February 18, 1997
    Assignee: Yason S.r.l.
    Inventor: Giuseppe Quadro, deceased
  • Patent number: 5352703
    Abstract: 2-benzoylamino-3,5-dibromo-N-(4-hydroxycyclohexyl)benzylamine of formula (I), and pharmaceutically acceptable acid addition salts have antitussive and mucus regulating activities.
    Type: Grant
    Filed: November 23, 1992
    Date of Patent: October 4, 1994
    Assignee: Mediolanum Farmaceutici S.p.A.
    Inventor: Giuseppe Quadro
  • Patent number: 5312825
    Type: Grant
    Filed: September 3, 1992
    Date of Patent: May 17, 1994
    Assignee: Yason S.r.l.
    Inventor: Giuseppe Quadro
  • Patent number: 5244897
    Abstract: A pharmaceutical composition (orally or parenterally administered) containing glycyl-p-amino-pyridine monoacetate alone or together suitable carriers, which shows surprising anti-amnesic and anti-Alzheimer properties, is described.
    Type: Grant
    Filed: June 2, 1992
    Date of Patent: September 14, 1993
    Assignee: Medea Research S.r.l.
    Inventor: Giuseppe Quadro
  • Patent number: 5055488
    Abstract: 3-Methyl-3-(4-acetylaminophenoxy)-2,4-dioxabenzocyclohexanone-1, having formula I ##STR1## exhibits an high analgesic, antiinflammatory and antipiretic activity along with a prolonged action and an excellent gastric and systemic tolerability.
    Type: Grant
    Filed: July 31, 1987
    Date of Patent: October 8, 1991
    Assignee: Medea Research S.r.l.
    Inventor: Giuseppe Quadro
  • Patent number: 4956389
    Abstract: Compound of general formula I ##STR1## and its addition salts with a pharmaceutically acceptable acid is described. The compound is prepared by reacting bis-(2-(3,4-dimethoxy-phenyl)ethyl)amine with formaldehyde in a reducing medium. The compound is effective in the treatment of cardiovascular diseases and disturbances in cerebral circulation.
    Type: Grant
    Filed: January 14, 1985
    Date of Patent: September 11, 1990
    Assignees: Yason S.R.L., SIR International S.A.
    Inventors: Giuseppe Quadro, Jean Cahn
  • Patent number: 4874776
    Abstract: N-carbethoxy-4-thiazolidine-carboxylic acid of formula I ##STR1## and the alkali, alkali-earth of basic amino acid salts thereof have therapeutic activities in the affections of respiratory system.
    Type: Grant
    Filed: July 11, 1988
    Date of Patent: October 17, 1989
    Assignee: Yason S.r.l.
    Inventor: Giuseppe Quadro
  • Patent number: 4839366
    Abstract: The compound of formula (I): ##STR1## N-cyclohexyl-N"-4-(2-methylthioquinolyl)-N'-2-thiazolyl-guanidine and pharmaceutically acceptable salts thereof is a valuable antiinflammatory, analgesic and antipyretic agent.The compound of the invention may be formulated with conventional pharmaceutically acceptable carriers or diluents to provide a pharmaceutical composition.
    Type: Grant
    Filed: February 23, 1988
    Date of Patent: June 13, 1989
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventor: Giuseppe Quadro
  • Patent number: 4826856
    Abstract: The compound I ##STR1## prepared by reacting m-nitrobenzaldehyde, ethyl .beta.-aminocrotonate and 2-piperidinoethanol acetoacetate, is endowed with valuable pharmacological properties namely calcium antagonistic activity in vitro and in vivo.
    Type: Grant
    Filed: February 18, 1988
    Date of Patent: May 2, 1989
    Assignees: Yason s.r.l., Sir International SA, Henning Berlin GmbH
    Inventors: Giuseppe Quadro, Jean Cahn
  • Patent number: 4447419
    Abstract: The present invention relates to the 3-[N-(2-mercapto-propionyl-amino-acetyl)]-tetrahydro-thiazolyl-4-carboxyli c acid and pharmaceutical compositions containing it, endowed with a marked inhibitory activity of the angiotensin converting enzyme (ACE).
    Type: Grant
    Filed: November 1, 1982
    Date of Patent: May 8, 1984
    Assignee: Ausonia Farmaceutici s.r.l.
    Inventor: Giuseppe Quadro
  • Patent number: 4379091
    Abstract: The present invention concerns tetraethylene glycol monoesters with 2-arylpropionic acids (known as anti-inflammatory agents). Said esters, while being endowed with the characteristics of low toxicity and gastric injuring effects shown by the related acids, differ advantageously from the latter because their anti-inflammatory activity is much more prolonged, and their bioavailability markedly better.
    Type: Grant
    Filed: February 11, 1981
    Date of Patent: April 5, 1983
    Assignee: Ausonia Farmaceutici s.r.l.
    Inventors: Paolo Ferruti, Ferdinando Danusso, Maria C. Tanzi, Giuseppe Quadro
  • Patent number: 4367176
    Abstract: The present invention concerns diesters of polyethylene glycols (with n ranging between 4 approximately and 100 approximately) with 2-arylpropionic acids (known as anti-inflammatory agents). These esters, while possessing all the characteristics of low toxicity and gastric injuring effects shown by the related acids, differ advantageously from the latter because their anti-inflammatory activity is much more prolonged, and their bio-availability markedly better.
    Type: Grant
    Filed: February 11, 1981
    Date of Patent: January 4, 1983
    Assignee: Ausonia Farmaceutici s.r.l.
    Inventors: Paolo Ferruti, Ferdinando Danusso, Maria C. Tanzi, Giuseppe Quadro
  • Patent number: 4358444
    Abstract: 3-(2-Methoxy-phenoxy)-3-methyl-benzo-2,4-dioxacyclohexanone of formula ##STR1## a process for its preparation through reaction among the chloride of acetylsalicylic acid, guaiacole and pyridine; pharmaceutical compositions containing it.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: November 9, 1982
    Assignee: Dr. L. Zambeletti S.p.A.
    Inventor: Giuseppe Quadro
  • Patent number: 4305940
    Abstract: Benzamides of formula I ##STR1## are described, in which R=CH.sub.3, Cl or COOCH.sub.3 ; R' is a member selected from the group of dialkylamine, pyrrolidine, piperidine, and morpholine radicals. CH.sub.2 R' is in position ortho, meta, or para with respect to the carbonyl group; and their salts thereof with pharmaceutically acceptable acids are described. The novel compounds exhibit local anaesthetic and antiarrhythmic activity.
    Type: Grant
    Filed: November 18, 1980
    Date of Patent: December 15, 1981
    Assignee: B.B.R. Boehringer Biochemia Robin S.p.A.
    Inventor: Giuseppe Quadro
  • Patent number: 4221805
    Abstract: Compositions useful for platelet antiaggregation activity are described, which contain as the active ingredient N-(2-chlorobenzyl)-pyrrolidine or a pharmacologically compatible salt thereof with an organic or an inorganic acid, and at least one pharmaceutically acceptable carrier or excipient. The compositions in the form of an aqueous solution are administered orally in the dose of 2-8 mgs/kg, preferably 3 mgs/kg body weight twice a day. The compositions may also be administered intravenously or endoperitoneally. The compositions may be administered in the form of capsules, ampoules or in the form of oily suspensions, solutions or emulsions.
    Type: Grant
    Filed: July 24, 1978
    Date of Patent: September 9, 1980
    Inventor: Giuseppe Quadro