Patents by Inventor Giuseppina Visentin

Giuseppina Visentin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100069317
    Abstract: This invention relates to a novel crystalline polymorphic form of nemorubicin hydrochloride dihydrate, useful for the preparation of pharmaceutical composition for the treatment of tumors. A process for preparing this novel polymorphic form, named form A, is within the scope of the present invention.
    Type: Application
    Filed: June 29, 2007
    Publication date: March 18, 2010
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Romualdo FORINO, Natale Alvaro BARBUGIAN, Attilio TOMASI, Giuseppina VISENTIN, Marco CATTANEO, Massimo ZAMPIERI
  • Patent number: 6420379
    Abstract: The present invention relates to alkynyl-substituted camptothecins of formula (I) wherein X, R1, R2 are as defined herein, and the pharmaceutically salts thereof. These compounds are useful in therapy as antitumor agents.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: July 16, 2002
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Ilaria Candiani, Angelo Bedeschi, Giuseppina Visentin, Maria Chiara Fagnola, Laura Capolongo
  • Patent number: 6211192
    Abstract: The present invention relates to alkynyl-substituted camptothecins of formula (I) wherein X, R1, R2 are as defined herein, and the pharmaceutically salts thereof. These compounds are useful in therapy as antitumor agents.
    Type: Grant
    Filed: August 12, 1999
    Date of Patent: April 3, 2001
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Ilaria Candiani, Angelo Bedeschi, Giuseppina Visentin, Maria Chiara Fagnola, Laura Capolongo
  • Patent number: 5856496
    Abstract: A process for preparing libraries of indole compounds by solid phase synthesis in the presence of organometallic catalysts. The resulting compounds have a very high purity degree, which allows biological testing on the crude products with a high confidence degree, without any cross contaminations.
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: January 5, 1999
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Maria Chiara Fagnola, Angelo Bedeschi, Ilaria Candiani, Giuseppina Visentin, Nicola Mongelli
  • Patent number: 5480880
    Abstract: The invention provides compounds of the general formula I ##STR1## wherein R.sub.1 is a hydrogen atom, a negative charge or an ester residue; R is:a) --(CH.sub.2).sub.n --A--CO.sub.2 H, --(CH.sub.2)n--A--SO.sub.3 H or --(CH.sub.2).sub.n --A--PO.sub.3 H.sub.2, wherein n is either zero, one or two and A is a group --CH.dbd.CH-- (either E or Z), --OCH.sub.2 --, --SCH.sub.2 -- or --CHOH--;b) --(CH.sub.2).sub.n --PO.sub.3 H.sub.2, --(CH.sub.2).sub.n SO.sub.2 NHCN, --(CH.sub.2).sub.n NHSO.sub.3 H, --(CH.sub.2).sub.n CONHSO.sub.2 CH.sub.3 or --(CH.sub.2).sub.n CONHSO.sub.2 CF.sub.3, wherein n is as defined above;c) --(CH.sub.2 S).sub.m --W--(CH.sub.2).sub.n Z, wherein W is an arylene group or a heterocyclediyl group, m is 0 or 1, n is as above defined, and Z represents CO.sub.2 H, PO.sub.3 H.sub.2, SO.sub.2 NHCN, NHSO.sub.3 H, CONHSO.sub.2 CH.sub.3 or CONHSO.sub.2 CF.sub.3 ;d) ##STR2## wherein Y is O or NH and X is NH, N--OH or N--O--(CH.sub.2).sub.n+1 COOH wherein n is as defined above; ore) --(CH.sub.2 S).sub.
    Type: Grant
    Filed: April 9, 1993
    Date of Patent: January 2, 1996
    Assignee: Farmitalia Carlo Erba S.r.l.
    Inventors: Giuseppina Visentin, Franco Zarini, Daniela Jabes, Ettore Perrone, Costantino della Bruna, Marco Alpegiani
  • Patent number: 4868338
    Abstract: The acylation of a naphthalene compound, substituted in the 2-position with an electron-donating group, with a reactive derivative of a lower aliphatic acid, in an aprotic organic diluent and in the presence of a Friedel Crafts catalyst consisting of a halide of an element having at least two valences, is improved when maintaining constant at any time the molar ratio of the naphthalene compound to the acylating agent and that of the acylating agent to the Friedel Crafts catalyst within specific ranges.
    Type: Grant
    Filed: March 8, 1988
    Date of Patent: September 19, 1989
    Assignee: Blaschim S.p.A.
    Inventors: Ambrogio Magni, Giuseppina Visentin
  • Patent number: 4864063
    Abstract: Process for preparing Naproxen via a sequence of stereospecific reactions which comprises: condensation of 1-chloro-2-methoxy-naphthalene with a (S)-2-halo-propionyl halide according to the Friedel-Crafts reaction, ketalization of the thus obtained (S)-2-halo-1-(5'-chloro-6'-methoxy-2'-naphthyl)propan-1-one, rearrangement of said ketal to afford an ester, hydrolysis of the ester and removal of the chlorine atom in 5-position by hydrogenolysis.New (S) 2-halo-1-(5'-chloro-6'-methoxy-2'-naphthyl)propan-1-ones.
    Type: Grant
    Filed: December 23, 1987
    Date of Patent: September 5, 1989
    Inventors: Oreste Piccolo, Ermanno Valoti, Giuseppina Visentin
  • Patent number: 4736061
    Abstract: Process for preparing Naproxen via a sequence of stereospecific reactions which comprises: condensation of 1-chloro-2-methoxy-naphthalene with a (S)-2-halo-propionyl halide according to the Friedel-Crafts reaction, ketalization of the thus obtained (S)-2-halo-1-(5'-chloro-6'-methoxy-2'-naphthyl)-propan-1-one, rearrangement of said ketal to afford an ester, hydrolysis of the ester and removal of the chlorine atom in 5-position by hydrogenolysis.New (S) 2-halo-1-(5'-chloro-6'-methoxy-2'-naphthyl)-propan-1-ones.
    Type: Grant
    Filed: May 10, 1985
    Date of Patent: April 5, 1988
    Assignee: Blaschim S.p.A.
    Inventors: Oreste Piccolo, Ermanno Valoti, Giuseppina Visentin
  • Patent number: 4670603
    Abstract: Preparation of aryl alkyl ketones by reaction of an aryl compound with an aliphatic acid and/or a functional derivative thereof in anhydrous hydrofluoric acid.
    Type: Grant
    Filed: September 24, 1985
    Date of Patent: June 2, 1987
    Assignee: Blaschim S.p.A.
    Inventors: Oreste Piccolo, Giuseppina Visentin, Pietro Blasina, Franca Spreafico