Patents by Inventor Glauco R. Souza
Glauco R. Souza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12044676Abstract: Cells are grown in 3D culture and topological features obtained by photomicrography are correlated to cell viability and cell interactions.Type: GrantFiled: April 9, 2019Date of Patent: July 23, 2024Assignee: GREINER BIO-ONE NORTH AMERICA, INC.Inventor: Glauco R. Souza
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Patent number: 10844365Abstract: Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly.Type: GrantFiled: March 5, 2018Date of Patent: November 24, 2020Assignees: William Marsh Rice University, The Board of Regents of the University of Texas SystemInventors: Glauco R. Souza, Renata Pasqualini, Wadih Arap, Thomas Charles Killian, Robert M. Raphael, Daniel Joshua Stark
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Publication number: 20190242881Abstract: Cells are grown in 3D culture and topological features obtained by photomicrography are correlated to cell viability and cell interactions.Type: ApplicationFiled: April 9, 2019Publication date: August 8, 2019Inventor: Glauco R. Souza
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Patent number: 10288603Abstract: Cells are grown in 3D culture and topological features obtained by photomicrography are correlated to cell viability and cell cell interactions.Type: GrantFiled: January 13, 2012Date of Patent: May 14, 2019Assignee: Greiner Bio-One North America, Inc.Inventor: Glauco R. Souza
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Patent number: 10265396Abstract: Methods of making and using a magnetic ECM are disclosed. The ECM comprises positively and negatively charged nanoparticles, wherein one of said nanoparticles contains a magnetically responsive element. When the magnetic ECM is seeded with cells, the cells will be magnetized and can be levitated for 3-D cell culture.Type: GrantFiled: September 18, 2017Date of Patent: April 23, 2019Assignee: Greiner Bio-One North America, Inc.Inventor: Glauco R. Souza
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Publication number: 20180265858Abstract: Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly.Type: ApplicationFiled: March 5, 2018Publication date: September 20, 2018Inventors: Glauco R. SOUZA, Renata Pasqualini, Wadih ARAP, Thomas Charles KILLIAN, Robert M. RAPHAEL, Daniel Joshua STARK
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Patent number: 9909116Abstract: Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly.Type: GrantFiled: July 15, 2014Date of Patent: March 6, 2018Assignee: WILLIAM MARSH RICE UNIVERSITYInventors: Glauco R Souza, Renata Pasqualini, Wadih Arap, Thomas Charles Killian, Robert M. Raphael, Daniel Joshua Stark
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Publication number: 20180000936Abstract: Methods of making and using a magnetic ECM are disclosed. The ECM comprises positively and negatively charged nanoparticles, wherein one of said nanoparticles contains a magnetically responsive element. When the magnetic ECM is seeded with cells, the cells will be magnetized and can be levitated for 3-D cell culture.Type: ApplicationFiled: September 18, 2017Publication date: January 4, 2018Inventor: Glauco R. SOUZA
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Patent number: 9764030Abstract: Methods of making and using a magnetic ECM are disclosed. The ECM comprises positively and negatively charged nanoparticles, wherein one of said nanoparticles contains a magnetically responsive element. When the magnetic ECM is seeded with cells, the cells will be magnetized and can be levitated for 3-D cell culture.Type: GrantFiled: June 11, 2013Date of Patent: September 19, 2017Assignee: Nano3D Biosciences IncInventor: Glauco R. Souza
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Patent number: 9731391Abstract: Camera phone accessories for using the camera phone to collect scientific data.Type: GrantFiled: April 22, 2013Date of Patent: August 15, 2017Assignee: Nano3D Biosciences Inc.Inventors: Glauco R. Souza, Jianbo Chen
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Patent number: 9688955Abstract: A material comprising positively and negatively charged nanoparticles, wherein one of said nanoparticles contained a magnetically responsive element, are combined with a support molecule, which is a long natural or synthetic molecule or polymer to make a magnetic nanoparticle assembly. When the magnetic nanoparticle assembly is combined with cells, it will magnetize those cells. The magnetized cells can then be washed to remove the magnetic nanoparticle assembly and the magnetized cells manipulated in a magnetic field.Type: GrantFiled: November 7, 2014Date of Patent: June 27, 2017Assignee: Nano3D Biosciences, Inc.Inventor: Glauco R. Souza
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Publication number: 20150110752Abstract: Methods of making and using a magnetic ECM are disclosed. The ECM comprises positively and negatively charged nanoparticles, wherein one of said nanoparticles contains a magnetically responsive element. When the magnetic ECM is seeded with cells, the cells will be magnetized and can be levitated for 3-D cell culture.Type: ApplicationFiled: June 11, 2013Publication date: April 23, 2015Inventor: Glauco R. Souza
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Publication number: 20150104844Abstract: A material comprising positively and negatively charged nanoparticles, wherein one of said nanoparticles contained a magnetically responsive element, are combined with a support molecule, which is a long natural or synthetic molecule or polymer to make a magnetic nanoparticle assembly. When the magnetic nanoparticle assembly is combined with cells, it will magnetize those cells. The magnetized cells can then be washed to remove the magnetic nanoparticle assembly and the magnetized cells manipulated in a magnetic field.Type: ApplicationFiled: November 7, 2014Publication date: April 16, 2015Inventor: Glauco R. SOUZA
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Publication number: 20150091233Abstract: Camera phone accessories for using the camera phone to collect scientific data.Type: ApplicationFiled: April 22, 2013Publication date: April 2, 2015Inventors: Glauco R. Souza, Jianbo Chen
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Patent number: 8883471Abstract: A material comprising positively and negatively charged nanoparticles, wherein one of said nanoparticles contained a magnetically responsive element, are combined with a support molecule, which is a long natural or synthetic molecule or polymer to make a magnetic nanoparticle assembly. When the magnetic nanoparticle assembly is combined with cells, it will magnetize those cells. The magnetized cells can then be washed to remove the magnetic nanoparticle assembly and the magnetized cells manipulated in a magnetic field.Type: GrantFiled: September 27, 2010Date of Patent: November 11, 2014Assignee: N3D Biosciences, Inc.Inventor: Glauco R. Souza
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Publication number: 20140322784Abstract: Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly.Type: ApplicationFiled: July 15, 2014Publication date: October 30, 2014Inventors: Glauco R. SOUZA, Renata Pasqualini, Wadih ARAP, Thomas Charles KILLIAN, Robert M. RAPHAEL, Daniel Joshua STARK
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Patent number: 8815231Abstract: Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly.Type: GrantFiled: March 24, 2011Date of Patent: August 26, 2014Assignees: William Marsh Rice University, Board of Regents, The University of Texas SystemInventors: Glauco R. Souza, Renata Pasqualini, Wadih Arap, Thomas Charles Killian, Robert M. Raphael, Daniel Joshua Stark
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Publication number: 20130280754Abstract: Cells are grown in 3D culture and topological features obtained by photomicrography are correlated to cell viability and cell cell interactions.Type: ApplicationFiled: January 13, 2012Publication date: October 24, 2013Applicant: Nano3D Biosciences, Inc.Inventor: Glauco R. Souza
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Publication number: 20120171744Abstract: A material comprising positively and negatively charged nanoparticles, wherein one of said nanoparticles contained a magnetically responsive element, are combined with a support molecule, which is a long natural or synthetic molecule or polymer to make a magnetic nanoparticle assembly. When the magnetic nanoparticle assembly is combined with cells, it will magnetize those cells. The magnetized cells can then be washed to remove the magnetic nanoparticle assembly and the magnetized cells manipulated in a magnetic field.Type: ApplicationFiled: September 27, 2010Publication date: July 5, 2012Applicant: N3D BIOSCIENCES, INC.Inventor: Glauco R. Souza
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Publication number: 20110286975Abstract: Systems and methods generally useful in medicine, cellular biology, nanotechnology, and cell culturing are discussed. In particular, at least in some embodiments, systems and methods for magnetic guidance and patterning of cells and materials are discussed. Some specific applications of these systems and methods may include levitated culturing of cells away from a surface, making and manipulating patterns of levitated cells, and patterning culturing of cells on a surface. Specifically, a method of culturing cells is presented. The method may comprise providing a plurality of cells, providing a magnetic field, and levitating at least some of the plurality of cells in the magnetic field, wherein the plurality of cells comprise magnetic nanoparticles. The method may also comprise maintaining the levitation for a time sufficient to permit cell growth to form an assembly.Type: ApplicationFiled: March 24, 2011Publication date: November 24, 2011Inventors: Glauco R. Souza, Renata Pasqualini, Wadih Arap, Thomas Charles Killian, Robert M. Raphael, Daniel Joshua Stark