Abstract: A method for controlling and monitoring instrumentation for a multilayer tablet press mechanism is disclosed. The compression for each layer, other than the first, takes the measured variable or error from the previous layer control loop and applies a transformation to that variable or error. The resulting transformation is then used as a compensation to the subsequent layer control loop in the form of a modified set point, modified measure variable, modified error, or modified control output. Additionally, the variable or error resulting from the previous control loop is fed back into the controller for the previous control loop so that any adjustments necessary in the previous layer loop may be completed. The variable or error is also used to determine whether to accept or reject the tablet.