Abstract: The present patent application discloses the compounds according to Formula I shown below, or pharmaceutically acceptable salts thereof, wherein JB, n, R1, R2, R3, R4, R5, m and X as defined herein.

Abstract: A temperature modulation assembly and a multi-layer retention mechanism for such a temperature therapy device are disclosed. According to one embodiment, a temperature modulation assembly for a temperature therapy device has a heat spreader and a mounting plate coupled to a bottom portion of a spacer, wherein the heat spreader is disposed between the mounting plate and the spacer. The temperature modulation assembly has a heatsink and a fan coupled to a top portion of the spacer, wherein the heatsink is disposed between the top portion of the spacer and the fan. The temperature modulation assembly further includes a heating and/or cooling device disposed within a central opening of the spacer, wherein the heating and/or cooling device is located between the heatsink and the heat spreader.

Abstract: A pressure relief valve configured to vent a pressurized tank in the event of a fire is provided. The pressure relief valve includes a body, a vent passage, a plug and a latch. The vent passage is disposed through the body. The vent passage can be placed in fluid communication with an internal volume of a tank and with the atmosphere. The plug is moveably mounted in the vent passage. The latch has a blocking member disposed in contact with a control end of the plug in a first configuration and out of contact with the control end in a second configuration. The second configuration allows movement of the plug in the vent passage. One or both of a shape memory alloy wire and a trigger piston is configured to actuate the latch from the first to the second configuration. The shape memory alloy wire is configured to shorten when exposed to a temperature above a threshold temperature. The trigger piston moves, e.g.

Abstract: A pressure relief valve configured to vent a pressurized tank in the event of a fire is provided. The pressure relief valve includes a body, a vent passage, a plug and a latch. The vent passage is disposed through the body. The vent passage can be placed in fluid communication with an internal volume of a tank and with the atmosphere. The plug is moveably mounted in the vent passage. The latch has a blocking member disposed in contact with a control end of the plug in a first configuration and out of contact with the control end in a second configuration. The second configuration allows movement of the plug in the vent passage. One or both of a shape memory alloy wire and a trigger piston is configured to actuate the latch from the first to the second configuration. The shape memory alloy wire is configured to shorten when exposed to a temperature above a threshold temperature. The trigger piston moves, e.g.

Abstract: A temperature therapy system and a method for temperature control for such a temperature therapy system are disclosed. According to one embodiment, a temperature therapy system has a retention mechanism and a plurality of temperature modulation systems attached to the retention mechanism, wherein each of the plurality of temperature modulation systems comprises a thermoelectric cooler. The wearable personal temperature therapy system may have a plurality of temperature sensors and a plurality of conductive flags, wherein each of the plurality of conductive flags is adhered to a respective thermoelectric cooler and a respective temperature sensor.

Abstract: A therapeutic device for applying vibration, thermal and compressive therapy is disclosed. According to one embodiment, the device has a top layer and a bottom layer adapted to contact a body surface of a user. The device further includes a therapeutic element disposed between the top layer and the bottom layer, the therapeutic element including a vibration component, a thermal component, and a compression component, where, upon activation of the therapeutic element: (i) the vibration component applies a vibration force, (ii) the thermal component applies a thermal therapy, and (iii) the compression component applies a compressive force.

Abstract: A massage applicator including a housing, a piston having a proximal end and a distal end, a motor within the housing operatively connected to the piston, wherein the motor is configured to cause the piston to reciprocate, an applicator controller configured to operate the motor, and an attachment head releasably coupled to the piston so as to be located at the distal end of the piston, the attachment head including at least one sensor configured to collect sensor data, wherein the applicator controller is configured to adjust operation of the motor based on the collected sensor data.

Abstract: A temperature modulation assembly and a multi-layer retention mechanism for such a temperature therapy device are disclosed. According to one embodiment, a temperature modulation assembly for a temperature therapy device has a heat spreader and a mounting plate coupled to a bottom portion of a spacer, wherein the heat spreader is disposed between the mounting plate and the spacer. The temperature modulation assembly has a heatsink and a fan coupled to a top portion of the spacer, wherein the heatsink is disposed between the top portion of the spacer and the fan. The temperature modulation assembly further includes a heating and/or cooling device disposed within a central opening of the spacer, wherein the heating and/or cooling device is located between the heatsink and the heat spreader.

Abstract: A temperature therapy system and a method for temperature control for such a temperature therapy system are disclosed. According to one embodiment, a temperature therapy system has a retention mechanism and a plurality of temperature modulation systems attached to the retention mechanism, wherein each of the plurality of temperature modulation systems comprises a thermoelectric cooler. The wearable personal temperature therapy system may have a plurality of temperature sensors and a plurality of conductive flags, wherein each of the plurality of conductive flags is adhered to a respective thermoelectric cooler and a respective temperature sensor.

Abstract: A wing, buoyant in water has an upper wing surface comprising a deck upon which a rider stands, and, the wing is in water. A foot constraint proximate the wing leading edge and fixedly attaching the wing projects outwardly from the deck to release-ably receive the rider's forward foot. With the rider standing with both feet upon the deck, and the rider's forward foot ensconced within the foot constraint, and with the rider's aft foot proximate a trailing edge of the wing, the rider bodily heaves and pitches the wing to obtain a chordwise forward velocity thru the water. The forward foot constraint enables the rider to upheave the wing. A second foot constraint may attach the deck proximate the wing trailing edge. Another foot constraining system is comprised as a frictional device broadly applying the deck, and, may be used in addition to or in lieu of other constraints.

Abstract: Systems and methods for providing vibration and temperature therapy via a therapy device is disclosed. According to one embodiment, a therapy device includes a pad comprising an adhesive layer configured to adhere to a skin surface of a user. The therapy device includes a control unit coupled to the pad. The control unit is configured to provide temperature therapy to the skin surface of the user and provide vibration therapy to the skin surface of the user. The pad includes a coupling connector configured to removably couple the control unit. The pad can include a heat generation module comprising a resistive wire and a heat spreader. The pad can include one or more electrical stimulation modules, wherein each electrical stimulation module comprises a conductor and a pad. The pad includes a temperature sensor coupled to the heat generation module. The adhesive layer can be coupled to the heat spreader.

Abstract: According to some aspects, a method of monitoring an acoustic environment of a mobile device, at least one computer readable medium encoded with instructions that, when executed, perform such a method and/or a mobile device configured to perform such a method is provided. The method comprises receiving acoustic input from the environment of the mobile device while the mobile device is operating in the low power mode, detecting whether the acoustic input includes a voice command based on performing a plurality of processing stages on the acoustic input, wherein at least one of the plurality of processing stages is performed while the mobile device is operating in the low power mode, and using at least one contextual cue to assist in detecting whether the acoustic input includes a voice command.

Abstract: A device for applying compressive therapy is disclosed. According to one embodiment, the device has a top layer and a bottom layer adapted to contact a body surface of a user. The device further includes a compressive element disposed between the top layer and the bottom layer, where the compressive element is configured such that, upon activation of the compressive element: (i) a compressive force is applied to the body surface and (ii) the compressive element curves to more closely conform to the bottom layer.

Abstract: A pressure relief valve configured to vent a pressurized tank in the event of a fire is provided. The pressure relief valve includes a body, a vent passage, a plug and a latch. The vent passage is disposed through the body. The vent passage can be placed in fluid communication with an internal volume of a tank and with the atmosphere. The plug is moveably mounted in the vent passage. The latch has a blocking member disposed in contact with a control end of the plug in a first configuration and out of contact with the control end in a second configuration. The second configuration allows movement of the plug in the vent passage. One or both of a shape memory alloy wire and a trigger piston is configured to actuate the latch from the first to the second configuration. The shape memory alloy wire is configured to shorten when exposed to a temperature above a threshold temperature. The trigger piston moves, e.g.

Abstract: A fuel system is provided that includes a fuel tank, a heat detector, and a control circuit. The digital heat detector is disposed in proximity to the fuel tank. The control circuit is coupled with the digital heat detector and is configured to detect that a thermal event has occurred. The fuel system is configured to implement an emergency countermeasure in response to the detection of the thermal event.

Abstract: A pressure relief valve configured to vent a pressurized tank in the event of a fire is provided. The pressure relief valve includes a body, a vent passage, a plug and a latch. The vent passage is disposed through the body. The vent passage can be placed in fluid communication with an internal volume of a tank and with the atmosphere. The plug is moveably mounted in the vent passage. The latch has a blocking member disposed in contact with a control end of the plug in a first configuration and out of contact with the control end in a second configuration. The second configuration allows movement of the plug in the vent passage. One or both of a shape memory alloy wire and a trigger piston is configured to actuate the latch from the first to the second configuration. The shape memory alloy wire is configured to shorten when exposed to a temperature above a threshold temperature. The trigger piston moves, e.g.

Abstract: According to some aspects, a method of monitoring an acoustic environment of a mobile device, at least one computer readable medium encoded with instructions that, when executed, perform such a method and/or a mobile device configured to perform such a method is provided. The method comprises receiving acoustic input from the environment of the mobile device while the mobile device is operating in the low power mode, detecting whether the acoustic input includes a voice command based on performing a plurality of processing stages on the acoustic input, wherein at least one of the plurality of processing stages is performed while the mobile device is operating in the low power mode, and using at least one contextual cue to assist in detecting whether the acoustic input includes a voice command.

Abstract: A pressure relief valve configured to vent a pressurized tank in the event of a fire is provided. The pressure relief valve includes a body, a vent passage, a plug and a latch. The vent passage is disposed through the body. The vent passage can be placed in fluid communication with an internal volume of a tank and with the atmosphere. The plug is moveably mounted in the vent passage. The latch has a blocking member disposed in contact with a control end of the plug in a first configuration and out of contact with the control end in a second configuration. The second configuration allows movement of the plug in the vent passage. One or both of a shape memory alloy wire and a trigger piston is configured to actuate the latch from the first to the second configuration. The shape memory alloy wire is configured to shorten when exposed to a temperature above a threshold temperature. The trigger piston moves, e.g.

Abstract: A fuel system is provided that includes a fuel tank, a heat detector, and a control circuit. The digital heat detector is disposed in proximity to the fuel tank. The control circuit is coupled with the digital heat detector and is configured to detect that a thermal event has occurred. The fuel system is configured to implement an emergency countermeasure in response to the detection of the thermal event.

Abstract: A log scanning system and method for scanning a log load. Each individual log in the log load may have an ID element with a unique log ID data on at least one log end face. The system has a handheld scanner unit for free-form scanning by an operator over a load end face of the log load. The scanner unit has a depth sensor configured to capture a series of depth images of the load end face and a texture sensor configured to capture a series of texture images of the load end face during the load end face scan. The system also has a data processor(s) that receives and processes the depth and texture images captured from the scan.