Patents by Inventor Glen Ernst

Glen Ernst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Pyrazole Derivatives And Their Use As Modulators Of Nicotinic Acetylcholine Receptors
    Publication number: 20080081833
    Abstract: Compounds of Formula I: wherein A1, A2, D and E are as described in the specification, pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially for treatment of conditions associated with reductions in nicotinic transmission.
    Type: Application
    Filed: December 16, 2005
    Publication date: April 3, 2008
    Applicant: AstraZeneca AB
    Inventors: Glen Ernst, William Frietze, Thomas Simpson
  • Nicotinic Acetylcholine Receptor Ligands
    Publication number: 20070270458
    Abstract: Compounds of formula I: wherein D, Ar1, E and Ar2 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
    Type: Application
    Filed: December 20, 2004
    Publication date: November 22, 2007
    Inventors: Glen Ernst, Robert Jacobs, Eifion Phillips
  • Nicotinic Acetylcholine Receptor Ligands
    Publication number: 20070249588
    Abstract: Acetylcholine receptor ligands of formula (I), wherein D, Ar1, E and Ar2 are as described in the specification, diastereoisomers, enantiomers, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: December 20, 2004
    Publication date: October 25, 2007
    Applicant: AstraZeneca AB
    Inventors: Glen Ernst, William Frietze, Robert Jacobs, Eifion Phillips
  • Nicotinic AcetylcholineReceptor Ligands
    Publication number: 20070244097
    Abstract: Acetylcholine receptor ligands of formula I wherein D, E and G are as described in the specification, diastereoisomers, enantiomers, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: December 20, 2004
    Publication date: October 18, 2007
    Applicant: AstraZeneca AB
    Inventors: Glen Ernst, William Frietze, Robert Jacobs, Eifion Phillips
  • Compounds for the inhibition of nitric oxide synthase
    Patent number: 7276528
    Abstract: There are provided novel compounds of formula (I) wherein A, R1, R3, R4, R5, T, U, V, W, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory diseases, pain and CNS diseases.
    Type: Grant
    Filed: May 25, 2006
    Date of Patent: October 2, 2007
    Assignee: AstraZeneca AB
    Inventors: Stephen Connolly, Glen Ernst
  • Nicotinic acetylcholine receptor ligands
    Publication number: 20070191422
    Abstract: Compounds of formula (I), wherein D, Ar1, E and Ar2 are as defined in the specification, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, especially in the treatment or prophylaxis of psychotic and intellectual impairment disorders.
    Type: Application
    Filed: December 20, 2004
    Publication date: August 16, 2007
    Applicant: AstraZeneca AB
    Inventors: Glen Ernst, Robert Jacobs, Eifion Phillips
  • Non-amide nonanes
    Publication number: 20070043031
    Abstract: Compounds of Formula I: and pharmaceutically-acceptable salts thereof, wherein Q, E and D are as defined in the specification, enantiomers, in vivo-hydrolysable precursors, pharmaceutical compositions and formulations containing them, methods of using them to treat diseases and conditions either alone or in combination with other therapeutically-active compounds or substances, processes and intermediates used to prepare them and uses of them for diagnostic and analytic purposes.
    Type: Application
    Filed: September 24, 2004
    Publication date: February 22, 2007
    Applicant: AstraZeneca AB
    Inventors: Glen Ernst, Eifion Phillips, Richard Schmiesing
  • Compounds for the inhibition of nitric oxide synthase
    Patent number: 7119122
    Abstract: There are provided novel compounds of formula (I) wherein A, R1, R3, R4, R5, T, U, V, W, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: October 10, 2006
    Assignee: Astrazeneca AB
    Inventors: Stephen Connolly, Glen Ernst
  • Compounds for the inhibition of nitric oxide synthase
    Publication number: 20060217424
    Abstract: There are provided novel compounds of formula (I) wherein A, R1, R3, R4, R5, T, U, V, W, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory diseases, pain and CNS diseases.
    Type: Application
    Filed: May 25, 2006
    Publication date: September 28, 2006
    Inventors: Stephen Connolly, Glen Ernst
  • Aryl-substituted diazabicycloalkanes as nicotinic acetylcholine agonists
    Publication number: 20060052368
    Abstract: Nicotinic acetylcholine receptor agonists of formula I wherein a, b, c, D and R are as defined in the specification, enantiomers, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 13, 2003
    Publication date: March 9, 2006
    Inventors: Glen Ernst, Eifion Phillips, Richard Schmiesing
  • Biaryl diazabicycloalkane amides as nicotinic acetylcholine agonists
    Publication number: 20050239774
    Abstract: Acetylcholine receptor ligands of formula I wherein A, D, Ar1, E and Ar2 are as described in the specification, diastereoisomers, enantiomers, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same.
    Type: Application
    Filed: August 13, 2003
    Publication date: October 27, 2005
    Inventors: Glen Ernst, Eifion Phillips
  • N-type calcium channel antagonists for the treatment of pain
    Patent number: 6906193
    Abstract: Compounds useful for the treatment of pain in accord with the following structural diagram, wherein R1, R2, R3, R4 and R5 are any of a number of groups as defined in the specification, A and D are as defined in the specification, and pharmaceutical compositions and methods of treatment utilising such compounds.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: June 14, 2005
    Assignee: AstraZeneca AB
    Inventors: Glen Ernst, Marc Chapdelaine, Dannielle Kissel, Greg Hostetler, John McCauley
  • Novel compounds
    Publication number: 20040260088
    Abstract: There are provided novel compounds of formula (I) wherein A, R1, R3, R4, R5, T, U, V, W, X and Y are as defined in the specification, and pharmaceutically acceptable salts thereof; together with processes for their preparation, compositions containing them and their use in therapy. The compounds are inhibitors of nitric oxide synthase and are thereby particularly useful in the treatment or prophylaxis of inflammatory diseases, pain and CNS diseases.
    Type: Application
    Filed: March 30, 2004
    Publication date: December 23, 2004
    Inventors: Stephen Connolly, Glen Ernst
  • N-type calcium channel antagonists for the treatment of pain
    Publication number: 20040053964
    Abstract: Compounds useful for the treatment of pain in accord with the following structural diagram, 1
    Type: Application
    Filed: September 29, 2003
    Publication date: March 18, 2004
    Inventors: Glen Ernst, Marc Chapdelaine, Dannielle Kissel, Greg Hostetler, John McCauley