Abstract: A flow cell subassembly includes a carriage assembly coupled to a flow cell body to selectively engage a nozzle with a base of a cuvette. The carriage assembly includes a linear bearing slidingly engaged with the flow cell body, a tiltable carriage plate coupled to the linear bearing, and a nozzle mount coupled to the tiltable carriage plate. The nozzle mount receives a nozzle assembly with the nozzle. Set screws can adjust pitch angle of the tiltable carriage plate with the linear bearing to adjust engagement between the nozzle and cuvette in a first dimension. To adjust engagement between the nozzle and cuvette in a second dimension, axial play in bolts/screws through the tiltable carriage plate into threaded holes of the linear bearing allow for yaw angle adjustments.

Abstract: A compact sorting flow cytometer system is disclosed. The system includes a fluidics system having a flow cell and a deflection chamber in communication with the flow cell to receive drops in a stream of a sample biological fluid with one or more biological cells or particles and selectively deflect the drops in the stream of the sample biological fluid with the one or more biological cells or particles; and a droplet deposition unit (DDU) system in communication with the deflection chamber to receive the selectively deflected drops in the stream of the sample biological fluid with the one or more biological cells or particles into one or more containers.

Abstract: A compact sorting flow cytometer system is disclosed. The system includes a fluidics system having a flow cell and a deflection chamber in communication with the flow cell to receive drops in a stream of a sample biological fluid with one or more biological cells or particles and selectively deflect the drops in the stream of the sample biological fluid with the one or more biological cells or particles; and a droplet deposition unit (DDU) system in communication with the deflection chamber to receive the selectively deflected drops in the stream of the sample biological fluid with the one or more biological cells or particles into one or more containers.

Abstract: An acoustic device is provided comprising a reservoir adapted to contain a fluid and having an exterior surface, an acoustic radiation generator for generating acoustic radiation, and a means for delivering an acoustic coupling fluid to the exterior surface of the reservoir. The acoustic radiation generator is placed in acoustic coupling relationship via the acoustic coupling fluid to the reservoir. Acoustic radiation generated by the acoustic radiation generator is transmitted through the exterior surface and into any fluid contained in the reservoir. Uncontrolled flow of the acoustic coupling fluid at the exterior surface as a result of movement of the acoustic radiation generator is eliminated. Also provided are methods that eliminate such uncontrolled flow.

Abstract: An acoustic device is provided comprising a reservoir adapted to contain a fluid and having an exterior surface, an acoustic radiation generator for generating acoustic radiation, and a means for delivering an acoustic coupling fluid to the exterior surface of the reservoir. The acoustic radiation generator is placed in acoustic coupling relationship via the acoustic coupling fluid to the reservoir. Acoustic radiation generated by the acoustic radiation generator is transmitted through the exterior surface and into any fluid contained in the reservoir. Uncontrolled flow of the acoustic coupling fluid at the exterior surface as a result of movement of the acoustic radiation generator is eliminated. Also provided are methods that eliminate such uncontrolled flow.