Abstract: Methods of probing a material under investigation using an ultrasound beam. Echolocation data is generated using a multi-dimensional transform capable of using phase and magnitude information to distinguish echoes resulting from ultrasound beam components produced using different ultrasound transducers. Since the multi-dimensional transform does not depend on using receive or transmit beam lines, a multi-dimensional area can be imaged using a single ultrasound transmission. In some embodiments, this ability increases image frame rate and reduces the amount of ultrasound energy required to generate an image.

Abstract: Embodiments of the present invention provide a service to goods and/or service providers and consumers in the traditional context of a “first-come, first-served queue” or “class based” queue. A provider presents a listing of one or offerings to consumers to solicit bids for a good or service associated with the offering. After receiving an acceptable bid from a user, the provider provides feedback regarding the bid that indicates the ranking of the user with respect to other bidders in the bidding process. Based on the feedback, the user may submit a modified bid. Following confirmation of a bid by a user, a winning bid is determined and the user is notified.

Abstract: Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.

Abstract: Embodiments of the present invention provide a service to goods and/or service providers and consumers in the traditional context of a “first-come, first-served queue” or “class based” queue. A provider presents a listing of one or offerings to consumers to solicit bids for a good or service associated with the offering. After receiving an acceptable bid from a user, the provider provides feedback regarding the bid that indicates the ranking of the user with respect to other bidders in the bidding process. Based on the feedback, the user may submit a modified bid. Following confirmation of a bid by a user, a winning bid is determined and the user is notified.

Abstract: Embodiments of the invention provide apparatus, systems and methods for the detection of deep vein thrombosis (DVT) using photoacoustic measurement of hemoglobin in different states of oxgyenation within tissue. One embodiment of a system for DVT detection comprises at least a first and second light source that emit light at first and second wavelengths, an acoustic transducer, a data converter and a processor. The first and second light sources are directed on the patient's skin to produce a photoacoustic signal (PS) correlated to an amount of absorbance of the first and second wavelengths by a target region of tissue beneath the patient's skin. The acoustic transducer detects the PS and transduces it into an electrical signal which is correlated to the PS. The data converter converts the electrical signal into a digital signal which is analyzed by the processor to detect the presence of DVT within the target region.

Abstract: Echolocation data is generated using a multi-dimensional transform capable of using phase and magnitude information to distinguish echoes resulting from ultrasound beam components produced using different ultrasound transducers. Since the multi-dimensional transform does not depend on using receive or transmit beam lines, a multi-dimensional area can be imaged using a single ultrasound transmission. In some embodiments, this ability increases image frame rate and reduces the amount of ultrasound energy required to generate an image.

Abstract: Methods of probing a material under investigation using an ultrasound beam. Echolocation data is generated using a multi-dimensional transform capable of using phase and magnitude information to distinguish echoes resulting from ultrasound beam components produced using different ultrasound transducers. Since the multi-dimensional transform does not depend on using receive or transmit beam lines, a multi-dimensional area can be imaged using a single ultrasound transmission. In some embodiments, this ability increases image frame rate and reduces the amount of ultrasound energy required to generate an image.

Abstract: Methods of probing a material under investigation using an ultrasound beam. Echolocation data is generated using a multi-dimensional transform capable of using phase and magnitude information to distinguish echoes resulting from ultrasound beam components produced using different ultrasound transducers. Since the multi-dimensional transform does not depend on using receive or transmit beam lines, a multi-dimensional area can be imaged using a single ultrasound transmission. In some embodiments, this ability increases image frame rate and reduces the amount of ultrasound energy required to generate an image.

Abstract: A system for ultrasonic imaging utilizing multiple sets of transmit pulses differing in amplitude, frequency, phase, and/or pulse width. One embodiment has phase differences between the k transmit signal as 360 k ? ? degrees providing for constructive interference of the kth order harmonic pulse, while an amplitude modulation of each transmit profile is constant between sets. These sets of pulses are transmitted into media of interest and received echoes from these pulses are combined to form an averaged signal. The averaged pulses represent the net common mode signal received from each of the transmit sets. This combined signal set is used to reconstruct an ultrasound image based on broad beam reconstruction methodology.

Abstract: An ultrasound imaging system configured to simultaneously acquire and process multi-mode and multi-band echo information from a single set of pulse firings is provided. Raw ultrasound signals are digitized and stored in an I/Q data buffer. The stored data are then parallel preprocessed as a function of frequency band or alternative encoding. Parallel preprocessing optionally includes manipulating the data in respect to different imaging modes. Outputs of the parallel preprocessors are coupled to separate area formers used to simultaneously reconstruct various desired echo information to form a multi-mode or multi-band image. The echo formation process is optionally performed in parallel.

Abstract: Systems of generating and manipulating an ultrasound beam are disclosed. The system uses selective sets of ultrasound elements to generate an ultrasound beam, scanning the beam over a series of ultrasound elements in order to collected echo data covering an area, and generating an image from the resulting data. The scanning process includes shifting the set of ultrasound elements used to form the ultrasound beam by more than one ultrasound element (block-switching) between each step in the scanning process. This is accomplished without loss of image resolution by using area-forming techniques. The block-switching technique enables use of cross-correlation methods during image construction.

Abstract: A system for ultrasonic imaging utilizing multiple sets of transmit pulses differing in amplitude, frequency, phase, and/or pulse width. One embodiment has phase differences between the k transmit signal as 360 k degrees providing for constructive interference of the kth order harmonic pulse, while an amplitude modulation of each transmit profile is constant between sets. These sets of pulses are transmitted into media of interest and received echoes from these pulses are combined to form an averaged signal. The averaged pulses represent the net common mode signal received from each of the transmit sets. This combined signal set is used to reconstruct an ultrasound image based on broad beam reconstruction methodology.

Abstract: Systems of generating and manipulating an ultrasound beam are disclosed. The system uses selective sets of ultrasound elements to generate an ultrasound beam, scanning the beam over a series of ultrasound elements in order to collected echo data covering an area, and generating an image from the resulting data. The scanning process includes shifting the set of ultrasound elements used to form the ultrasound beam by more then one ultrasound element (block-switching) between each step in the scanning process. This is accomplished without loss of image resolution by using area-forming techniques. The block-switching technique enables use of cross-correlation methods during image construction.

Abstract: A portable ultrasound unit and docking cart for the unit are provided. When the portable unit is mounted to the docking cart, the docking cart transforms the portable unit into a cart-based system with enhanced features and functionality such as improved ergonomics, ease of use, a larger display format, external communications connectivity, multiple transducer connections, and increased data processing capabilities. A clinician display and patient display may be provided on the cart. Communications circuitry in the docking cart may be used to support communications between the docking cart's processor and external networks and devices. The docking cart may receive physiological signals such as cardiac signals and may use this information to synchronize ultrasound imaging operations with a patient's physiological condition. Adjustable user interface controls, data handling features, security features, power control functions, and thermal management capabilities may be provided in the docking cart.

Abstract: A portable ultrasound unit and docking cart for the unit are provided. When the portable unit is mounted to the docking cart, the docking cart transforms the portable unit into a cart-based system with enhanced features and functionality such as improved ergonomics, ease of use, a larger display format, external communications connectivity, multiple transducer connections, and increased data processing capabilities. A clinician display and patient display may be provided on the cart. Communications circuitry in the docking cart may be used to support communications between the docking cart's processor and external networks and devices. The docking cart may receive physiological signals such as cardiac signals and may use this information to synchronize ultrasound imaging operations with a patient's physiological condition. Adjustable user interface controls, data handling features, security features, power control functions, and thermal management capabilities may be provided in the docking cart.

Abstract: Methods of probing a material under investigation using an ultrasound beam. Echolocation data is generated using a multi-dimensional transform capable of using phase and magnitude information to distinguish echoes resulting from ultrasound beam components produced using different ultrasound transducers. Since the multi-dimensional transform does not depend on using receive or transmit beam lines, a multi-dimensional area can be imaged using a single ultrasound transmission. In some embodiments, this ability increases image frame rate and reduces the amount of ultrasound energy required to generate an image.

Abstract: Embodiments of the invention provide methods and apparatus for suturing tissue penetrations made during minimally invasive surgery. One embodiment of an apparatus for suturing tissue penetrations comprises a shaft, suture capture surface coupled to the shaft, and at least one pair of needles or other penetrating members advanceable from the shaft. The shaft can be detachably coupled to a hand-piece. The surface has a deployed and a non-deployed configuration and is configured to capture a suture in the deployed configuration and retain it in the non-deployed configuration. The surface can be deployed by a frame or other expandable structure. The penetrating members are configured to be coupled to a suture and are advanceable from the shaft by an advancement member or other means to deliver a suture end portion to the deployed surface. Sutures can be contained in a replaceable cartridge detachably coupled to the apparatus.

Abstract: Methods of probing a material under investigation using an ultrasound beam. Echolocation data is generated using a multi-dimensional transform capable of using phase and magnitude information to distinguish echoes resulting from ultrasound beam components produced using different ultrasound transducers. Since the multi-dimensional transform does not depend on using receive or transmit beam lines, a multi-dimensional area can be imaged using a single ultrasound transmission. In some embodiments, this ability increases image frame rate and reduces the amount of ultrasound energy required to generate an image.

Abstract: Ultrasonic imaging utilizing multiple sets of transmit pulses differing in amplitude, frequency, phase, and/or pulse width is disclosed. One embodiment has phase differences between the k transmit signal as 360 k ? ? d ? ? e ? ? g ? ? r ? ? e ? ? e ? ? s providing for constructive interference of the kth order harmonic pulse, while an amplitude modulation of each transmit profile is constant between sets. These sets of pulses are transmitted into media of interest and received echoes from these pulses are combined to form art averaged signal. The averaged pulses represent the net common mode signal received from each of the transmit sets. This combined signal set is used to reconstruct an ultrasound image based on broad beam reconstruction methodology.

Abstract: An ultrasound reconstruction unit is provided. In one embodiment, a receive aperture control engine for the unit adaptively determines a set of reconstruction signals based on at least a series of selected echo signals and compares the size of a receive aperture with a predetermined number of reconstruction channels at each imaging point. The unit passes the selected echo signals from selected receive channels of one or more transducer elements to a reconstruction processor if the size of the receive aperture is not greater than the number of reconstruction channels. In another embodiment, the control engine compares the size of the receive aperture with a predetermined number of reconstruction channels at each imaging point and preprocess the selected echo signals to produce reconstructions signals that are equal in number to the number of reconstruction channels if the size of the receive aperture is greater than the number of reconstruction channels.