Patents by Inventor Glen T. Gaughan

Glen T. Gaughan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel human nucleic acid molecules and polypeptides encoding a novel human ion channel expressed in spinal cord and brain
    Publication number: 20030027164
    Abstract: The present invention relates to novel human nucleic acid molecules encoding novel human cation channels, and proteins and polypeptides encoded by such nucleic acid molecules. More specifically, the nucleic acid molecules of the invention include novel human genes, e.g., hVR1d.1 and hVR1d.2, that encode proteins or polypeptides that are expressed in spinal cord and brain tissues and display sequence homology and structural homology to the vanilloid and TRP (transient receptor potential) families of cation channel proteins. The proteins and polypeptides of the invention directed to this novel human cation channel may be therapeutically valuable targets for drug delivery in the treatment of human diseases that involve calcium, sodium, potassium or other ionic homeostatic dysfunction, such as central nervous system (CNS) disorders, e.g.
    Type: Application
    Filed: November 30, 2001
    Publication date: February 6, 2003
    Inventors: Glen T. Gaughan, John N. Feder, Thomas C. Nelson, Gabe Mintier, Chandra S. Ramanathan
  • Novel human nucleic acid molecules and polypeptides encoding cation channels
    Publication number: 20020072101
    Abstract: The present invention relates to novel human nucleic acid molecules encoding novel human cation channels, and proteins and polypeptides encoded by such nucleic acid molecules. More specifically, the nucleic acid molecules of the invention include novel human genes, e.g., hCCh3.1, hCCh3.2, and hCCh4, that encode proteins or polypeptides that display some sequence homology and structural homology to the vanilloid and TRP (transient receptor potential) families of cation channel proteins. The proteins and polypeptides of the invention represent novel cation channels that may be therapeutically valuable targets for drug delivery in the treatment of human diseases which involve calcium, sodium, potassium or other ionic homeostatic dysfunction, such as central nervous system (CNS) disorders, e.g., stroke or degenerative neurological disorders such as Alzheimer's disease, or other disorders such as cardiac disorders, e.g.
    Type: Application
    Filed: January 18, 2001
    Publication date: June 13, 2002
    Inventors: Glen T. Gaughan, Chandra S. Ramanathan
  • Method for imaging and radiopharmaceutical therapy using 1-substituted-4,7,10-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
    Patent number: 6143274
    Abstract: A method for imaging mammalian tissue utilizing a non-ionic complex of a paramagnetic ion of lanthanide element and a macrocyclic chelating agent.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: November 7, 2000
    Inventors: Michael F. Tweedle, Glen T. Gaughan, James J. Hagan
  • Method for imaging mammalian tissue using 1-substituted-1,4,7-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
    Patent number: 5846519
    Abstract: A method for imaging mammalian tissue utilizing a non-ionic complex of a paramagnetic ion of lanthanide element and a macrocyclic chelating agent.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 8, 1998
    Assignee: Bracco Diagnostics Inc.
    Inventors: Michael F. Tweedle, Glen T. Gaughan, James J. Hagan
  • Method for imaging mammalian tissue using 1-substituted- 4,7,10-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
    Patent number: 5674470
    Abstract: A method for imaging mammalian tissue utilizing a non-ionic complex of a paramagnetic ion of lanthanide element and a macrocyclic chelating agent.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 7, 1997
    Assignee: Bracco Diagnostics Inc.
    Inventors: Michael F. Tweedle, Glen T. Gaughan, James J. Hagan
  • Method for imaging mammalian tissue using 1-substituted-1,4,7-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
    Patent number: 5474756
    Abstract: A method for imaging mammalian tissue utilizing a non-ionic complex of a paramagnetic ion of lanthanide element and a macrocyclic chelating agent.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: December 12, 1995
    Assignee: Bracco International B.V.
    Inventors: Michael F. Tweedle, Glen T. Gaughan, James J. Hagan
  • 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
    Patent number: 4885363
    Abstract: Metal-chelating liquids having the formula ##STR1## wherein Y is oxygen or ##STR2## R.sub.
    Type: Grant
    Filed: December 23, 1987
    Date of Patent: December 5, 1989
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Michael F. Tweedle, Glen T. Gaughan, James T. Hagan