Abstract: The present invention provides an article picking and placing system, the system comprising: —a first article picking tooling and a second article picking tooling, and an intermediate transportation unit configured in between an article infeed transportation unit and an article outfeed transportation unit; —a control unit for synchronizing the first and second article picking tooling such that (i) the first article picking tooling picks and/or forms a first configuration of articles from the infeed transportation unit for transfer to the intermediate transportation unit, thereby forming an intermediate configuration on said intermediate transportation unit, and (ii) the second picking tooling picks a second configuration of articles from said intermediate transportation unit for transfer to the outfeed transportation unit, wherein the second and intermediate article configurations are different relative to each other and each different from the first article configuration.

Abstract: A product handling apparatus, systems and associated methods. A product handling apparatus, includes a continuous circuit having an infeed length; and a discharge length. A carriage configured to travel around the circuit between the infeed length and the discharge length has a first picking tool configured to selectively engage a first product; and a second picking tool configured to selectively engage a second product. The product handling apparatus is configured to pick a first and second product arranged in a first arrangement at the infeed length and place the first and second product in a second arrangement, different to the first arrangement, at the discharge length.

Abstract: A system for processing a packaging in assembly comprising a main transportation unit (102); and a manipulator transportation unit (104) having at least one manipulating unit (110), said manipulating unit mounted on at least one independently motion controlled mover (108) and adapted for manipulating a material component of a package (106) in assembly present at the main transportation unit, wherein said manipulating unit comprises an engagement device (112) for temporarily engaging a material component of a package in assembly while being in transit.

Abstract: A primary container handling system comprising a transportation unit transporting at least one container handling unit (108) mounted on at least one independently motion controlled mover or levitating tile (106), said container handling unit being configured to provide 3-dimensional translation and/or rotation of an individual primary container.

Abstract: The present invention provides a system for treating primary container packaging comprising •—a main transportation unit (102) configured to transport a number of gripping units (108) mounted on independently motion controlled movers (106), each gripping unit (108) adapted for transporting an individual primary container, •—an adjacent transportation unit (104) configured to transport a number of tools (114) mounted on independently motion controlled movers (112), said tools configured to provide one or more primary container material components to the main transportation unit and/or performing packaging process operations to the primary containers present at said main transportation unit.

Abstract: A packaging system has a system for assembling a package, a method for assembling a package, and a machine for assembling a package. The packaging system comprises at least one main transportation unit (104) and at least one moveable closed loop transportation unit (102), where the at least one moveable closed loop transportation unit (102) moves three-dimensionally with respect to the at least one main transportation unit (104) for providing the packaging material components to the main transportation unit (104) and/or performing packaging process operations to a package in assembly present at the main transportation unit (104). The at least one moveable closed loop transportation unit (102) includes a number of tools mounted on independently motion-controlled movers for providing the packaging material components to the package in assembly and/or providing the packaging operations to the packaging in assembly.

Abstract: The present disclosure relates to methods for making asunaprevir, useful treatment of Hepatitis C virus (HCV) infection, and its intermediates.

Abstract: The present disclosure relates to methods for making asunaprevir, useful treatment of Hepatitis C virus (HCV) infection, and its intermediates.

Abstract: A valve device for connecting two conduits in a unit for conducting a product comprises a first shut-off member and a second shut-off member and a first leakage space between the first and the second shut-off members, a first connection for one of the two conduits on a side of the first shut-off member facing away from the leakage space, and a second connection for the other of the two conduits on the side of the second shut-off member facing away from the leakage space. A third shut-off member and a fourth shut-off member and a second leakage space are present between the third and the fourth shut-off members, wherein a central third leakage space is present between the second and the third shut-off members, and wherein the second connection for the other of the two conduits is arranged on a side of the fourth shut-off member facing away from the second leakage space.

Abstract: A valve device for connecting two conduits in a unit for conducting a product comprises a first shut-off member and a second shut-off member and a first leakage space between the first and the second shut-off members, a first connection for one of the two conduits on a side of the first shut-off member facing away from the leakage space, and a second connection for the other of the two conduits on the side of the second shut-off member facing away from the leakage space. A third shut-off member and a fourth shut-off member and a second leakage space are present between the third and the fourth shut-off members, wherein a central third leakage space is present between the second and the third shut-off members, and wherein the second connection for the other of the two conduits is arranged on a side of the fourth shut-off member facing away from the second leakage space.