Patents by Inventor Glenn Jacobs

Glenn Jacobs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4918075
    Abstract: Antiviral activity is exhibited by compounds having the formula ##STR1## its pharmaceutically acceptable salts thereof wherein R.sub.2 and R.sub.3 are independently hydrogen, --PO.sub.3 H.sub.2 or ##STR2## and R.sub.1 is either a purine, pyrimidine or an analog thereof.
    Type: Grant
    Filed: December 20, 1988
    Date of Patent: April 17, 1990
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Robert Zahler, Glenn A. Jacobs
  • Patent number: 4855466
    Abstract: Disclosed are compounds having the formula ##STR1## wherein Prot is a hydroxyl protecting group. The compounds are useful as intermediates in the preparation of compounds of the formula ##STR2## which in turn are useful as antiviral agents.
    Type: Grant
    Filed: December 28, 1987
    Date of Patent: August 8, 1989
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Robert Zahler, Glenn A. Jacobs
  • Patent number: 4723002
    Abstract: Antibacterial activity is exhibited by 2-azetidinones having an acylamino substituent in the 3-position and having an activating group in the 1-position of the formula ##STR1##
    Type: Grant
    Filed: April 28, 1986
    Date of Patent: February 2, 1988
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Gregory S. Bisacchi, Glenn A. Jacobs, William H. Koster, Robert Zahler
  • Patent number: 4647660
    Abstract: Antibacterial activity is exhibited by 2-azetidinones activated in the 1-position with an --SO.sub.
    Type: Grant
    Filed: May 2, 1985
    Date of Patent: March 3, 1987
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Robert Zahler, Hermann Breuer, Glenn A. Jacobs
  • Patent number: 4279902
    Abstract: Acetamide derivatives are provided having the structure ##STR1## wherein X is a single bond, --CH.sub.2 -- or --O--, R.sup.1 and R.sup.2 may be the same or different and are lower alkyl, phenyl-lower alkoxy-lower alkyl, lower alkenyl, phenyl-lower alkyl or lower alkoxy, or ##STR2## may be taken together to form a 5- to 7-membered heterocyclic ring optionally containing one other hetero atom, such as nitrogen, sulfur or oxygen; Y is hydroxyl, OR wherein R is lower alkyl, lower alkenyl or lower alkanoyl, or ##STR3## wherein R.sup.1 and R.sup.2, and R.sup.1 and R.sup.2 taken together with the nitrogen to which they are attached are as defined above, and n is 1 to 6.These compounds are useful as anti-arrhythmia agents and have been found to be effective in the treatment of acute myocardial infarction.
    Type: Grant
    Filed: August 6, 1980
    Date of Patent: July 21, 1981
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frederic P. Hauck, Glenn A. Jacobs
  • Patent number: 4252801
    Abstract: Morpholinyl acetamide derivatives are provided having the structure ##STR1## wherein R is hydrogen, lower alkyl, lower alkenyl or lower alkanoyl, R.sup.1 and R.sup.2 may be the same or different and are lower alkyl, lower alkenyl, phenyl-lower alkyl or lower alkoxy, or ##STR2## may be taken together to form a 5- to 7-membered heterocyclic ring optionally containing one other hetero atom, such as nitrogen, sulfur or oxygen; Y is hydroxyl, OR wherein R is as defined above, or ##STR3## wherein R.sup.1 and R.sup.2 and R.sup.1 and R.sup.2 taken together with the nitrogen to which they are attached are as defined above, and n is 1 to 6.These compounds are useful as anti-arrhythmia agents and have been found to be effective in the treatment of acute myocardial infarction.
    Type: Grant
    Filed: January 4, 1980
    Date of Patent: February 24, 1981
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frederic P. Hauck, Glenn A. Jacobs
  • Patent number: 4241059
    Abstract: 6-[(Aryloxy)methyl]-2-morpholinemethanol derivatives are provided having the structure ##STR1## wherein R is hydrogen, lower alkyl, phenyl-lower alkyl, or lower alkenyl, and Ar represents a monocyclic or polycyclic aromatic group including tetraindiols and their analogs. These compounds are useful as adrenergic modifiers, particularly in treating arrhythmia.
    Type: Grant
    Filed: December 17, 1979
    Date of Patent: December 23, 1980
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Frederic P. Hauck, Glenn A. Jacobs
  • Patent number: D353889
    Type: Grant
    Filed: February 17, 1993
    Date of Patent: December 27, 1994
    Assignee: AMEI Technologies Inc.
    Inventors: John H. Erickson, John C. Tepper, Glenn Jacobs
  • Patent number: D361555
    Type: Grant
    Filed: February 17, 1993
    Date of Patent: August 22, 1995
    Assignee: AMEI Technologies Inc.
    Inventors: John H. Erickson, John C. Tepper, Mark A. Bettin, Robert W. Lee, Glenn Jacobs