Patents by Inventor Glenn McEnroe

Glenn McEnroe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxamide inhibitors of TGFbeta
    Publication number: 20060281763
    Abstract: Certain appropriately substituted forms of pyrimidine having a pyridylamine group at C-4 of the pyrimidine and an amide group on the pyridine ring are useful in the treatment of conditions associated with excessive TGF? activity.
    Type: Application
    Filed: March 27, 2006
    Publication date: December 14, 2006
    Inventors: Jonathan Axon, Sarvajit Chakravarty, Barry Hart, Glenn McEnroe, Alison Murphy, Karen Pontius, Peijue Sheng, Xiaojing Wang, Shanthi Yellapregada
  • Quinazoline derivatives as medicaments
    Publication number: 20050096333
    Abstract: Quinazoline derivatives have the formula: or the pharmaceutically acceptable salts thereof; wherein each of Z5, Z6, Z7 and Z8 is N or CH and wherein one or two Z5, Z6, Z7 and Z8 are N and wherein two adjacent Z positions cannot be N; wherein m and n are each independently 0-3; wherein R1 is independently OH, SH, NH2, OR, SR, NHR, halo or R-halide; wherein two adjacent R1 groups may be joined to form an aliphatic hetero cycle ring of 5-6 members; wherein R2 is independently R, halo, R-halide, OR-halide, NH2, CONH2 or CONHR; wherein R is optionally substituted C1-C12 alkyl, C1-C12 alkenyl, C1-C12 alkynyl, or aryl C1-C12 alkyl, containing 0-4 heteroatoms in place of a carbon in the carbon backbone, where the optional substituents are ?O, ?N, or OH; and wherein R3 is H or CH3. Such compounds are useful in pharmaceutical compositions and methods of treating conditions characterized by enhanced TGF? activity.
    Type: Application
    Filed: September 30, 2004
    Publication date: May 5, 2005
    Inventors: Sundeep Dugar, Sarvajit Chakravarty, Alison Murphy, Glenn McEnroe, Aurelia Conte, John Perumattam
  • Bi-cyclic pyrimidine inhibitors of TGFbeta
    Publication number: 20050004143
    Abstract: Compounds in which a pyrimidine nucleus is bridged at the 5 and 6 position and are further substituted at positions 2 and 4 with substituents comprising aromatic moieties are useful in treating subjects with conditions ameliorated by inhibition of TGF? activity.
    Type: Application
    Filed: March 26, 2004
    Publication date: January 6, 2005
    Inventors: Sundeep Dugar, Sarvajit Chakravarty, Aurelia Conte, Jonathan Axon, Glenn McEnroe, Alison Murphy
  • Piperidine/piperazine-type inhibitors of p38 kinase
    Publication number: 20040176382
    Abstract: The invention is directed to inhibition of p38-&agr; kinase using compounds of the formula 1
    Type: Application
    Filed: January 13, 2004
    Publication date: September 9, 2004
    Inventors: Babu Mavunkel, Sundeep Dugar, Gregory Luedtke, Glenn Mcenroe, Xuefei Tan
  • Inhibitors of TGFbeta
    Publication number: 20040132730
    Abstract: Certain appropriately substituted forms of pyrimidine and triazine are useful in the treatment to conditions associated with enhanced TGF&bgr; activity.
    Type: Application
    Filed: September 10, 2003
    Publication date: July 8, 2004
    Inventors: Jonathan Axon, Sarvajit Chakravarty, Sundeep Dugar, Glenn McEnroe, Alison Murphy
  • Piperidine/piperazine-type inhibitors of p38 kinase
    Patent number: 6696443
    Abstract: Certain compounds which contain a piperidine moiety flanked by aryl groups are inhibitors of p38-&agr; kinase and thus useful in the treatment of a variety of conditions characterized by inappropriate p38-&agr; kinase activity.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: February 24, 2004
    Assignee: Scios, Inc.
    Inventors: Babu Mavunkel, Sundeep Dugar, Gregory Luedtke, Xuefei Tan, Glenn McEnroe
  • Piperidine/piperazine-type inhibitors of p38 kinase
    Publication number: 20020198214
    Abstract: The invention is directed to inhibition of p38-&agr; kinase using compounds of the formula 1
    Type: Application
    Filed: November 20, 2001
    Publication date: December 26, 2002
    Inventors: Babu Mavunkel, Sundeep Dugar, Gregory Luedtke, Xuefei Tan, Glenn McEnroe