Patents by Inventor Glenn Prestwich

Glenn Prestwich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bioconjugates with chemically modified backbones
    Patent number: 11896642
    Abstract: Provided herein are synthetic bioconjugates comprising collagen-binding peptides covalently bound to chemically modified glycan backbones, compositions containing the same, and uses thereof.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: February 13, 2024
    Assignee: Symic Holdings, Inc.
    Inventors: John Eric Paderi, Glenn Prestwich, Katherine Allison Stuart, Harsha Kabra, Elvis Ikwa
  • Methods for preventing a serious health consequence and/or tissue damage after exposure to ionizing radiation and/or chemotherapy
    Patent number: 11642366
    Abstract: Described herein are methods for preventing a serious health consequence and/or tissue damage in a subject after the subject has been exposed to ionizing radiation and/or chemotherapy. The methods involve administering to the subject a sulfated polysaccharide or the pharmaceutically acceptable salt or ester thereof after the subject has been exposed to ionizing radiation and/or chemotherapy. The methods described herein are most beneficial to cancer patients who suffer from mucositis after exposure to ionizing radiation.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: May 9, 2023
    Assignee: GLYCOMIRA THERAPEUTICS, INC.
    Inventors: Won Yong Lee, Abigail Pulsipher, Thomas P. Kennedy, Justin Rodney Savage, Glenn Prestwich
  • HEPARIN-PEPTIDE BIOCONJUGATES AND USES THEREOF
    Publication number: 20220313830
    Abstract: Provided herein are bioconjugates comprising a glycan and from 1 to about 50 peptide(s) bound thereto, wherein the peptide(s) comprise a collagen-binding unit, hyaluronic acid-binding unit, an ICAM-binding unit, a VCAM-binding unit, and/or a selectin-binding unit, compositions containing the same, and uses thereof.
    Type: Application
    Filed: March 14, 2022
    Publication date: October 6, 2022
    Inventors: Glenn Prestwich, John Eric Paderi, Julia Chen, Rush Lloyd Bartlett, II
  • BIOCONJUGATES WITH CHEMICALLY MODIFIED BACKBONES
    Publication number: 20210290726
    Abstract: Provided herein are synthetic bioconjugates comprising collagen-binding peptides covalently bound to chemically modified glycan backbones, compositions containing the same, and uses thereof.
    Type: Application
    Filed: July 9, 2018
    Publication date: September 23, 2021
    Inventors: John Eric Paderi, Glenn Prestwich, Katherine Allison Stuart, Harsha Kabra, Elvis Ikwa
  • METHODS FOR PREVENTING A SERIOUS HEAL TH CONSEQUENCE AND/OR TISSUE DAMAGE AFTER EXPOSURE TO IONIZING RADIATION AND/OR CHEMOTHERAPY
    Publication number: 20210228618
    Abstract: Described herein are methods for preventing a serious health consequence and/or tissue damage in a subject after the subject has been exposed to ionizing radiation and/or chemotherapy. The methods involve administering to the subject a sulfated polysaccharide or the pharmaceutically acceptable salt or ester thereof after the subject has been exposed to ionizing radiation and/or chemotherapy. The methods described herein are most beneficial to cancer patients who suffer from mucositis after exposure to ionizing radiation.
    Type: Application
    Filed: June 3, 2019
    Publication date: July 29, 2021
    Inventors: Won Yong LEE, Abigail Pulsipher, Thomas P. Kennedy, Justin Rodney Savage, Glenn Prestwich
  • HEPARIN-PEPTIDE BIOCONJUGATES AND USES THEREOF
    Publication number: 20200078469
    Abstract: Provided herein are bioconjugates comprising a glycan and from 1 to about 50 peptide(s) bound thereto, wherein the peptide(s) comprise a collagen-binding unit, hyaluronic acid-binding unit, an ICAM-binding unit, a VCAM-binding unit, and/or a selectin-binding unit, compositions containing the same, and uses thereof.
    Type: Application
    Filed: April 19, 2019
    Publication date: March 12, 2020
    Inventors: Glenn Prestwich, John Eric Paderi, Julia Chen, Rush Lloyd Bartlett, II
  • Deuterium-enriched hyaluronan
    Patent number: 10398636
    Abstract: The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: September 3, 2019
    Assignee: Deuteria Biomaterials
    Inventor: Glenn Prestwich
  • DEUTERIUM-ENRICHED HYALURONAN
    Publication number: 20180256478
    Abstract: The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same.
    Type: Application
    Filed: December 19, 2017
    Publication date: September 13, 2018
    Inventor: Glenn Prestwich
  • Deuterium-enriched hyaluronan
    Patent number: 9849073
    Abstract: The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same.
    Type: Grant
    Filed: November 15, 2015
    Date of Patent: December 26, 2017
    Assignee: Deuteria Biomaterials, LLC
    Inventor: Glenn Prestwich
  • Use of alkylated semi-synthetic glycosaminoglycosan ethers for the treatment of inflammation
    Patent number: 9549945
    Abstract: Described herein are methods for treating inflammation in a subject comprising administering to the subject an effective amount of a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue is substituted with a C1-C10 unsubstituted alkyl group or fluoroalkyl group.
    Type: Grant
    Filed: February 4, 2015
    Date of Patent: January 24, 2017
    Assignee: University of Utah Research Foundation
    Inventors: Glenn Prestwich, Jianxing Zhang, Thomas P. Kennedy, Narayanam Rao
  • BIOCONJUGATES AND USES THEREOF
    Publication number: 20160331841
    Abstract: Provided herein are bioconjugates comprising a glycan and from 1 to about 50 peptide(s) bound thereto, wherein the peptide(s) comprise a collagen-binding unit, hyaluronic acid-binding unit, an ICAM-binding unit, a VCAM-binding unit, and/or a selectin-binding unit, compositions containing the same, and uses thereof.
    Type: Application
    Filed: April 15, 2016
    Publication date: November 17, 2016
    Inventors: Glenn Prestwich, John Eric Paderi, Julia Chen, Rush Lloyd Bartlett, II
  • DEUTERIUM-ENRICHED HYALURONAN
    Publication number: 20160206544
    Abstract: The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same.
    Type: Application
    Filed: November 15, 2015
    Publication date: July 21, 2016
    Inventor: Glenn Prestwich
  • Deuterium-enriched hyaluronan
    Patent number: 9187576
    Abstract: The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same.
    Type: Grant
    Filed: November 25, 2014
    Date of Patent: November 17, 2015
    Assignee: Deuteria Biomaterials, LLC
    Inventor: Glenn Prestwich
  • USE OF ALKYLATED SEMI-SYNTHETIC GLYCOSAMINOGLYCOSAN ETHERS FOR THE TREATMENT OF INFLAMMATION
    Publication number: 20150209385
    Abstract: Described herein are methods for treating inflammation in a subject comprising administering to the subject an effective amount of a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue is substituted with a C1-C10 unsubstituted alkyl group or fluoroalkyl group.
    Type: Application
    Filed: February 4, 2015
    Publication date: July 30, 2015
    Inventors: GLENN PRESTWICH, Jianxing ZHANG, Thomas P. KENNEDY, Narayanam RAO
  • DEUTERIUM-ENRICHED HYALURONAN
    Publication number: 20150148310
    Abstract: The present invention generally relates to deuterium-enriched hyaluronan, d-HA, compositions containing the same, methods of using the same, and methods for making the same.
    Type: Application
    Filed: November 25, 2014
    Publication date: May 28, 2015
    Inventor: Glenn Prestwich
  • Use of alkylated semi-synthetic glycosaminoglycosan ethers for the treatment of dental disorders
    Patent number: 8951990
    Abstract: Described herein are methods for treating a dental disorder in a subject comprising administering to the subject an effective amount of a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue is substituted with a C1-C10 unsubstituted alkyl group or fluoroalkyl group.
    Type: Grant
    Filed: January 7, 2013
    Date of Patent: February 10, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Glenn Prestwich, Jianxing Zhang, Sr., Thomas P. Kennedy, Narayanam Rao
  • Compositions for killing or preventing the growth of microbes
    Patent number: 8859760
    Abstract: Described herein are methods and compositions for killing or preventing the growth of microbes. It has been discovered that a class of porphyrins can kill or prevent the growth of microbes. The porphyrins can be used in a number of different applications where microbes grow.
    Type: Grant
    Filed: December 12, 2013
    Date of Patent: October 14, 2014
    Assignee: Frontier Scientific, Inc.
    Inventors: Glenn Prestwich, Jerry C. Bommer, Charles Testa
  • COMPOSITIONS FOR KILLING OR PREVENTING THE GROWTH OF MICROBES
    Publication number: 20140179742
    Abstract: Described herein are methods and compositions for killing or preventing the growth of microbes. It has been discovered that a class of porphyrins can kill or prevent the growth of microbes. The porphyrins can be used in a number of different applications where microbes grow.
    Type: Application
    Filed: December 12, 2013
    Publication date: June 26, 2014
    Applicant: Frontier Scientific, Inc.
    Inventors: Glenn PRESTWICH, Jerry C. BOMMER, Charles TESTA
  • Alpha-chloro and alpha-bromo phosphonate analogs of lysophosphatidic acid and methods of making and using thereof
    Patent number: 8722649
    Abstract: Described herein is the synthesis and pharmacology of a series of ?-substituted methylene phosphonate analogs, in which the ?-CH2 moiety is replaced with CHCl or CHBr.
    Type: Grant
    Filed: June 13, 2008
    Date of Patent: May 13, 2014
    Assignees: University of Utah Research Foundation, University of Tennessee Research Foundation
    Inventors: Glenn Prestwich, Gabor Tigyi, Guowei Jiang, Guanghui Yang, Joanna Gajewiak, Honglu Zhang, Xiaoyu Xu
  • Topical application of porphyrins for killing or preventing the growth of bacteria or fungi on a mammal
    Patent number: 8633311
    Abstract: Described herein are methods and compositions for killing or preventing the growth of microbes. It has been discovered that a class of porphyrins can kill or prevent the growth of microbes. The porphyrins can be used in a number of different applications where microbes grow.
    Type: Grant
    Filed: July 29, 2009
    Date of Patent: January 21, 2014
    Assignee: Frontier Scientific, Inc.
    Inventors: Jerry C. Bommer, Glenn Prestwich, Charles Testa