Abstract: A method to protect a host animal from flea infestation by treating that animal with a composition that includes a compound that reduces protease activity of fleas feeding from the treated animal, thereby reducing flea burden on the animal and in the environment of the animal. The present invention also relates to compositions including flea protease vaccines, anti-flea protease antibodies and/or protease inhibitors. Also included in the present invention are soluble flea midgut preparations, flea protease proteins, nucleic acid molecules encoding such proteins and antibodies that selectively bind to such proteins. The present invention also includes methods to obtain and use such preparations, proteins, nucleic acid molecules, antibodies and protease inhibitors to protect an animal from flea infestation.

Abstract: The present invention relates to parasite astacin metalloendopeptidase and filariid cysteine protease proteins, nucleic acid molecules having sequences that encode such proteins, antibodies raised against such proteins and compounds that can inhibit the activities of parasite astacin metalloendopeptidases or cysteine proteases. The present invention also includes methods to obtain such nucleic acid molecules, proteins, antibodies and inhibitors. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies and inhibitors as well as their use to protect animals from disease caused by parasites, such as heartworm.

Abstract: The present invention relates to flea serine protease and aminopeptidase proteins; to flea serine protease and aminopeptidase nucleic acid molecules, including those that encode such proteins; to antibodies raised against such proteins; and to compounds that inhibit flea serine protease and/or aminopeptidase activities. The present invention also includes methods to obtain such proteins, nucleic acid molecules, antibodies, and inhibitors. Also included in the present invention are therapeutic compositions comprising such proteins, nucleic acid molecules, antibodies, and/or inhibitors as well as the use of such therapeutic compositions to protect a host animal from flea infestation.

Abstract: The present invention relates to parasite astacin metalloendopeptidase and filariid cysteine protease proteins, nucleic acid molecules having sequences that encode such proteins, antibodies raised against such proteins and compounds that can inhibit the activities of parasite astacin metalloendopeptidases or cysteine proteases. The present invention also includes methods to obtain such nucleic acid molecules, proteins, antibodies and inhibitors. The present invention also includes therapeutic compositions comprising such nucleic acid molecules, proteins, antibodies and inhibitors as well as their use to protect animals from disease caused by parasites, such as heartworm.

Abstract: The present invention is directed to a novel product and method for isolating ectoparasite saliva proteins, and a novel product and method for detecting and/or treating allergic dermatitis in an animal. The present invention includes a saliva protein collection apparatus capable of collecting ectoparasite saliva proteins substantially free of contaminating material. The present invention also relates to ectoparasite saliva proteins, nucleic acid molecules having sequences that encode such proteins, and antibodies raised against such proteins. The present invention also includes methods to obtain such proteins and to use such proteins to identify animals susceptible to or having allergic dermatitis. The present invention also includes therapeutic compositions comprising such proteins and their use to treat animals susceptible to or having allergic dermatitis.

Abstract: An apparatus for driving the turbine and for purging debris from the air and water spray channels of an air driven turbine-type dental handpiece in preparation for sterilizing the handpiece includes a purging chamber for confining the aerosol together with any microorganisms, bacteria, or other contaminents issuing from a handpiece being purged.

Abstract: Method and apparatus for cleaning clogged dental equipment lines, such as water and air lines and drains, for a wide variety of dental equipment such as cuspidors and handpieces. One embodiment has an air hose connected to a connector for a handpiece for a drill, etc., wherein the connector has an interior plastic insert which closes off air to the holes in the drill for drive and exhaust air and allows air through two holes which connect with the spray air and water ports of the handpiece for the drill whererby the air blows out the clogged slits. Another embodiment uses the air hose with a rubber nozzle to blow clogged suction lines. Another embodiment has a rubber element with a hole in its middle which fits over the discharge hole in the cuspidor, whereby the air blows out the debris clogging the cuspidor hole and connecting lines.

Abstract: An apparatus for cleaning clogged dental equipment lines, such as water and air lines and drains, for a wide variety of dental equipment such as cuspidors and handpieces. One embodiment has an air hose connected to a connector for a handpiece for a drill, etc., wherein the connector has an interior plastic insert which closes off air to the holes in the drill for drive and exhaust air and allows air through two holes which connect with the spray air and water ports of the handpiece for the drill whereby the air blows out the clogged slits. Another embodiment uses the air hose with a rubber nozzle to blow clogged suction lines. Another embodiment has a rubber element with a hole in its middle which fits over the discharge hole in the cuspidor, whereby the air blows out the debris clogging the cuspidor hole and connecting lines.

Abstract: Method and apparatus for cleaning clogged dental equipment lines, such as water and air lines and drains, for a wide variety of dental equipment such as cuspidors and handpieces. One embodiment has an air hose connected to a connector for a handpiece for a drill, etc., wherein the connector has an interior plastic insert which closes off air to the holes in the drill for drive and exhaust air and allows air through two holes which connect with the spray air and water ports of the handpiece for the drill whereby the air blows out the clogged slits. Another embodiment uses the air hose with a rubber nozzle to blow clogged suction lines. Another embodiment has a rubber element with a hole in its middle which fits over the discharge hole in the cuspidor, whereby the air blows out the debris clogging the cuspidor hole and connecting lines.